A5032893370- Mycotoxins in Agriculture and Food
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Microbial infections and disease research
- Veterinary medicine and infectious diseases
- Insect and Pesticide Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Resistance in Bacteria
- Plant and fungal interactions
- Animal Nutrition and Physiology
- Coccidia and coccidiosis research
- Agricultural safety and regulations
- Pharmacological Effects and Assays
- Drug Transport and Resistance Mechanisms
- Veterinary Medicine and Surgery
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Wheat and Barley Genetics and Pathology
- Herpesvirus Infections and Treatments
- Carcinogens and Genotoxicity Assessment
- Pharmacogenetics and Drug Metabolism
- Plant Toxicity and Pharmacological Properties
- Veterinary Pharmacology and Anesthesia
- Animal Ecology and Behavior Studies
- Inflammatory mediators and NSAID effects
Ghent University
2016-2025
Ghent University Hospital
2006-2025
Salisbury University
2000-2025
Laboratory of Racing Chemistry
2023
Society of Environmental Toxicology and Chemistry
2020
University of Veterinary Medicine
2020
Shanghai Institutes for Biological Sciences
2017
Utrecht University
2012-2015
Royal Veterinary College
2011
Royal Sussex County Hospital
2011
ABSTRACT In broiler chickens, feed additives, including prebiotics, are widely used to improve gut health and stimulate performance. Xylo-oligosaccharides (XOS) hydrolytic degradation products of arabinoxylans that can be fermented by the microbiota. current study, we aimed analyze prebiotic properties XOS when added diet. Administration in addition a wheat-rye-based diet, significantly improved conversion ratio. increased villus length ileum. It also numbers lactobacilli colon Clostridium...
Broiler chickens are rather resistant to deoxynivalenol and thus, clinical signs rarely seen. However, effects of subclinical concentrations on both the intestine liver less frequently studied at molecular level. During our study, we investigated three weeks feeding gut wall morphology, intestinal barrier function inflammation in broiler chickens. In addition, oxidative stress was evaluated intestine. Besides, effect a clay-based mycotoxin adsorbing agent these different aspects also...
The first aim of the study was to investigate pharmacokinetics eight anticoagulant rodenticides (brodifacoum, bromadiolone, chlorophacinone, coumatetralyl, difenacoum, difethialone, flocoumafen and warfarin) in plasma liver mouse after single oral administration. Eight groups mice dosed orally with a different rodenticide dose equal one‐half lethal 50 (LD ), were killed at various times up 21 days assayed by an LC‐ESI‐MS/MS method. Depending on compound, limit quantification set 1 or 5 ng/mL...
Summary Sixteen butyrate‐producing bacteria were isolated from the caecal content of chickens and analysed phylogenetically. They did not represent a coherent phylogenetic group, but allied to four different lineages in Firmicutes phylum. Fourteen strains appeared novel species, based on level ≤ 98.5% 16S rRNA gene sequence similarity towards their nearest validly named neighbours. The highest butyrate concentrations produced by belonging clostridial clusters IV XIVa, which are predominant...
Both mycotoxin contamination of feed and Clostridium perfringens-induced necrotic enteritis have an increasing global economic impact on poultry production. Especially the Fusarium deoxynivalenol (DON) is a common contaminant. This study aimed at examining predisposing effect DON development in broiler chickens. An experimental perfringens infection revealed that DON, level 3,000 to 4,000 µg/kg feed, increased percentage birds with subclinical from 20±2.6% 47±3.0% (P<0.001). significantly...
Strains LMG 27428 T and 27427 were isolated from the caecal content of a chicken produced butyric, lactic formic acids as major metabolic end products. The genomic DNA G+C contents strains 40.4 38.8 mol%. On basis 16S rRNA gene sequence similarity, both most closely related to generically misclassified Streptococcus pleomorphus ATCC 29734 . Strain could be distinguished S. based on production more acid less in M2GSC medium, higher absence activities phosphatase leucine, arginine, leucyl...
Phytogenic products are embraced as alternatives to antimicrobials, and some known mitigate intestinal inflammation ensure optimal gut health performance in broiler chickens. Dietary inclusion of berberine, a benzylisoquinoline alkaloid found plants, is believed exert health-promoting effects through modulation the microbiota; however, there only few studies investigating its The aim this study was investigate interplay between dietary supplementation high concentration gastrointestinal...
Residues of the tetracycline group antibiotics were quantified in pork and chicken muscle tissue that had previously been screened with a microbiological inhibition test an immunological method. Pieces frozen meat on pH 6 culture medium seeded Bacillus subtilis. An aqueous extract inhibitor-positive samples was then group-specific commercial ELISA kit, able to detect levels oxytetracycline, chlortetracycline, doxycycline corresponding European MRL or lower. The cut-off value set at B/B0 75%....
Background and Aims Both deoxynivalenol (DON) nontyphoidal salmonellosis are emerging threats with possible hazardous effects on both human animal health. The objective of this study was to examine whether DON at low but relevant concentrations interacts the intestinal inflammation induced by Salmonella Typhimurium. Methodology By using a porcine ileal loop model, we investigated intake early inflammatory response Results A significant higher expression IL-12 TNFα clear potentiation IL-1β,...