Nicolas Gallastegui

ORCID: 0000-0003-3424-2924
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About
Contact & Profiles
Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Platelet Disorders and Treatments
  • Lymphoma Diagnosis and Treatment
  • Hemophilia Treatment and Research
  • CNS Lymphoma Diagnosis and Treatment
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Eosinophilic Disorders and Syndromes
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Viral-associated cancers and disorders
  • Diagnosis and Treatment of Venous Diseases
  • Chronic Lymphocytic Leukemia Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • COVID-19 and healthcare impacts
  • Hemoglobinopathies and Related Disorders
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cancer Immunotherapy and Biomarkers
  • T-cell and Retrovirus Studies
  • Nail Diseases and Treatments
  • Cutaneous lymphoproliferative disorders research
  • Immune Cell Function and Interaction
  • Multiple and Secondary Primary Cancers
  • Blood Coagulation and Thrombosis Mechanisms
  • COVID-19 Clinical Research Studies
  • Mast cells and histamine

Sylvester Comprehensive Cancer Center
2017-2024

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2023-2024

The Ohio State University Wexner Medical Center
2024

The Ohio State University
2023

University of California, San Diego
2020-2022

University of Miami
2013-2019

In-Q-Tel
2015

Jackson Memorial Hospital
2013-2015

The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease provide strategies the prevention, diagnosis, and treatment of venous thromboembolism (VTE) in adult patients with cancer. VTE is a common life-threatening condition cancer, its management often requires multidisciplinary efforts. panel comprised specialists spanning various fields, including cardiology, hematology, medical oncology, internal medicine, interventional radiology, pharmacology. content featured this issue...

10.6004/jnccn.2024.0046 article EN Journal of the National Comprehensive Cancer Network 2024-09-01

Given the paucity of data on higher-grade transformation (HGT) to aggressive lymphoma in patients with marginal zone (MZL), we report a large cohort patients, identify risk factors, and determine HGT impact overall survival (OS).

10.1200/jco.18.00138 article EN Journal of Clinical Oncology 2018-10-12

Between 11 and 37% of extranodal marginal zone lymphoma (EMZL) patients present with disease involvement in multiple mucosal sites (MMS). We analyzed 405 EMZL seen between 1995 2017: 265 (65.4%) presented stage I disease, 49 309 (15.8%) bone marrow involvement, 35 328 (10.7%) monoclonal gammopathy (MG). Forty-three (10.6%) had MMS presentation, which was more frequently aged >60 years (55.8%). Five (17.9%) 28 MG. commonly exhibited the International Prognostic Index (IPI) >2 (79.1%),...

10.1002/ajh.25446 article EN American Journal of Hematology 2019-02-20

Abstract Background The use of musculoskeletal ultrasound (MSKUS) for point-of-care (POC) evaluation hemophilic arthropathy is growing rapidly. However, the extent to which MSKUS influences clinical treatment decisions unknown. Methods We conducted a three-year, prospective, multi-center study at three hemophilia centers in United States evaluate utilization POC-MSKUS routine decision-making adult persons with arthropathy. Bilateral elbows, knees and ankles were assessed clinically...

10.1186/s12891-022-06042-w article EN cc-by BMC Musculoskeletal Disorders 2022-12-21

Leiomyosarcomas arising from the wall of blood vessels are rare and aggressive neoplasm. We report a case previously healthy 66-year-old woman who presented with intermittent abdominal pain, progressive constipation, weight loss. Abdominal computed tomography showed 12 cm solid heterogeneous tumor in tail pancreas. The patient subsequently underwent surgical resection pancreatic mass. Surprisingly, histological immunohistochemical analyses revealed leiomyosarcoma smooth muscle splenic vein....

10.4137/cmo.s12403 article EN cc-by-nc Clinical Medicine Insights Oncology 2013-01-01

Acquired haemophilia A (AHA) is a rare haemorrhagic disorder caused by the development of autoantibodies inhibiting factor VIII function. It predominantly affects elderly, who are often burdened with considerable number comorbidities, and can result in life-threatening bleeding. The management AHA consists two aspects: inhibitor eradication an immunomodulator bleed control bypassing agent. Here we present case high titre patient extensive comorbidities atrial fibrillation whom could not be...

10.12890/2021_002984 article EN PubMed 2021-01-01

Acquired haemophilia A (AHA) is a rare haemorrhagic disorder caused by the development of autoantibodies inhibiting factor VIII function. It predominantly affects elderly, who are often burdened with considerable number comorbidities, and can result in life-threatening bleeding. The management AHA consists two aspects: inhibitor eradication an immunomodulator bleed control bypassing agent. Here we present case high titre patient extensive comorbidities atrial fibrillation whom could not be...

10.12890/2021_002894 article EN cc-by-nc-nd European Journal of Case Reports in Internal Medicine 2021-11-11

Hypereosinophilia, as defined by the absolute eosinophil count ≥ 1,500 cells per microliter, can be a consequence of primary (clonal) hematologic disorders or secondary response to inflammation from allergens, parasitic infections, medications cancer. Its evaluation requires comprehensive history and physical well laboratory studies identify underlying cause assess for evidence end-organ damage in concern hypereosinophilia syndrome. Here, we report rare case paraneoplastic with an exceeding...

10.1016/j.cpccr.2023.100275 article EN cc-by-nc-nd Current Problems in Cancer Case Reports 2024-01-01

7559 Background: Marginal zone lymphomas (MZLs) are characterized by a long overall survival (OS). High-grade transformation (HGT) to aggressive lymphoma negatively impacts OS. Thus, identifying patients predisposed HGT is of utmost clinical importance. Given the paucity data on in MZL patients, we undertook retrospective study largest cohort date identify risk factors for and death, thought analyses transformation-free (TFS) Methods: In Florida Cancer Registry, identified 564 biopsy proven...

10.1200/jco.2018.36.15_suppl.7559 article EN Journal of Clinical Oncology 2018-05-20

Involvement of the central nervous system by chronic lymphocytic leukemia/small lymphoma is exceedingly rare, and currently no risk factors have been described. We report case a patient with concomitant an embolic cerebrovascular accident related to cardiac myxoma, who developed parenchymal involvement on ischemic bed. The was successfully treated high-dose fludarabine-based chemotherapy regimen, achieving sustained remission. propose that breakage blood-brain barrier may be major factor in...

10.1155/2019/1825491 article EN cc-by Case Reports in Hematology 2019-11-15

EVIDENCE-BASED MINIREVIEW| December 8, 2023 Should older patients with low weight and CKD receive full-dose DOACs for treatment of acute proximal DVT? Evidence-Based Minireview Nicolas Gallastegui, Gallastegui 1The James Comprehensive Cancer Institute, The Ohio State University, Columbus, OH Search other works by this author on: This Site PubMed Google Scholar Camila Masias 2Miami Baptist Health South Florida, Miami, FL Correspondence Masias, Miami 8900 N Kendall Dr, Office 2R220, FL;...

10.1182/hematology.2023000515 article EN Hematology 2023-12-08
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