A5048387009- Protein Hydrolysis and Bioactive Peptides
- Spinal Fractures and Fixation Techniques
- Fermentation and Sensory Analysis
- Traditional Chinese Medicine Analysis
- Food Quality and Safety Studies
- Heavy Metal Exposure and Toxicity
- Spine and Intervertebral Disc Pathology
- Selenium in Biological Systems
- Insect Utilization and Effects
- Medical Imaging and Analysis
- Nitric Oxide and Endothelin Effects
- Fungal Biology and Applications
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Cardiac Ischemia and Reperfusion
- Cervical and Thoracic Myelopathy
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Phytochemicals and Antioxidant Activities
- Biochemical Analysis and Sensing Techniques
- Cardiac Imaging and Diagnostics
- Aquaculture Nutrition and Growth
- Trace Elements in Health
- Biochemical effects in animals
- Tea Polyphenols and Effects
Lanzhou University
2018-2025
Lanzhou University Second Hospital
2018-2025
Shaoyang University
2019-2025
Yibin University
2025
Yibin Vocational and Technical College
2025
National Clinical Research
2024
Shenzhen Third People’s Hospital
2020-2024
Central South University of Forestry and Technology
2019-2024
Central South University
2019-2024
Shaoguan University
2024
It has been confirmed that mitochondrial impairment may underlie both sporadic and familial Parkinson’s disease (PD). Mitochondrial fission/fusion biogenesis are key processes in regulating homeostasis. Therefore, we explored whether the protective effect of resveratrol rotenone‐induced neurotoxicity was associated with biogenesis. The results showed could not only promote mass DNA copy number but also improve homeostasis neuron function rats PC12 cells damaged by rotenone. We observed...
Ganoderma lucidum (G. lucidum) has been widely used in Asia to treat hypertension, but the active substances responsible for its antihypertensive effects remain unclear. Using well-established angiotensin I-converting enzyme (ACE) as a target, we identified three ACE inhibitory peptides (ACEIPs), Gln-Leu-Val-Pro (QLVP), Gln-Asp-Val-Leu (QDVL), and Gln-Leu-Asp-Leu (QLDL), which account activity of G. lucidum. Notably, QLVP worked mixed-type manner against with an IC50 value 127.9 μmol/L....
Several publications report that octacosanol (OCT) has different biological functions. This study was designed to evaluate the antifatigue effect and molecular mechanism of (200 mg/(kg day)) in forced exercise-induced fatigue models trained male C57BL/6 mice. Results showed ameliorated mice's autonomic activities, forelimb grip strength, swimming endurance, levels liver glycogen (LG), muscle (MG), blood lactic acid (BLA), lactate dehydrogenase (LDH), superoxide dismutase (SOD), glutathione...
•Ultrafast ultrasound imaging is a new method to evaluate arterial stiffness with PWV.•The lack of reference values PWV has precluded its widespread clinical use.•This study established based on Han Chinese population.•Age, BP, and BMI were the dominant determinants PWV. BackgroundUltrafast been demonstrated be an effective carotid through pulse-wave velocity (PWV) high reproducibility, but use in practice. The aims this establish for ultrafast prospective, multicenter, population-based...
To enrich oligopeptides in sauce-aroma Baijiu, a mixed distillation process using the fermented grains from eighth-round fermentation of Baijiu brewing and residue soy sauce pressing was optimized. Under optimum conditions, peptide concentration distillate increased to 912.6 mg/L. Additionally, structural characterizations distillates were identified by liquid chromatography-mass spectrometry (LC-MS). Thirty-nine presented low mass, strong hydrophobicity, potential biological activity, such...
Endogenous peptides in Baijiu have primarily focused on finished liquor research, with limited attention given to the base prior blending. Liquid chromatography–tandem mass spectrometry (LC-MS) was employed identify endogenous distillates from first seventh rounds of soy sauce-flavored Baijiu. Two hundred and five oligopeptides were identified these distillates, all which had molecular weights below 1000 Da composed amino acid residues associated flavor (sweet, sour, bitter) biological...
In this work, we performed a theoretical calculation of the negative ion conversion by neutral carbon atom beam grazing scattering from KI(100) surface. The Madelung potential, image and ML–polarization interaction contributions are included in electron capture energy defect valence band near surface anion sites along projectile incidence direction. loss formed ions does not originate to unoccupied conduction or exciton states but results Coulomb barrier tunneling detachment loosely bound...
This study aimed to explore the potential antioxidant activity and mechanism of oligopeptides from sauce-aroma Baijiu. The Val-Leu-Pro-Phe (VLPF), Pro-Leu-Phe (PLF), Val-Gly-Phe-Cys (VGFC), Leu-Tyr-Pro (LYP), Leu-Pro-Phe (LPF), Phe-Thr-Phe (FTF) were identified by liquid chromatography–mass spectrometry (LC–MS) mixed-distillate Baijiu fermented grains soy sauce residue (MDFS). these on scavenging DPPH•, ABTS•+, hydroxide radicals was investigated, respectively. Among them, VGFC had strongest...
Summary R ‐phycoerythrin ( ‐ PE ) was purified from the red algae B angia fusco‐purpurea after 35–50% ammonium sulphate fractionation followed by ion‐exchange column chromatography on DEAE‐Sepharose, resulting in a purity (A 565 /A 280 ratio of 5.1. The circular dichroism spectroscopy results suggested that structure R‐PE is predominately helical. antioxidant activity studied and revealed changes conformation at different temperatures pH values. After vitro ‐simulated gastrointestinal (GI)...
Studies have shown that the peroxidation caused by oxygen free radicals is an important reason of vascular endothelial dysfunction and multiple diseases. In this study, active peptides (F2ds) were isolated from fermentation product rice dregs its antioxidant effects approved. Human umbilical vein cells (HUVECs) stimulated H 2 O used to evaluate antioxidation effect molecular mechanism in oxidative stress model. F2d protected ‐induced damage HUVECs a dosage‐dependent manner. can reduce...
In order to prepare angiotensin I-converting enzyme (ACE) inhibitory peptides, distilled spent grains of Chinese strong-flavor Baijiu were hydrolyzed by alcalase followed papain under optimized conditions. A superior ACE peptide was separated and purified ultrafiltration high-performance liquid chromatography (HPLC), its amino acid sequence further identified as Gln-Gly-Val-Pro (QGVP) electrospray mass spectrometry (ESI-MS). QGVP formed 6 hydrogen bonds with the active site ACE, which is...
Objectives This study aimed to explore the effects of astragaloside IV on metabolic syndrome induced by a high-fructose/high-fat diet in rats. Methods Rats were randomized into four groups: normal control, syndrome, + intraperitoneal 0.5 mg/kg/day, and 2.0 mg/kg/day (n=30 per group) for 14 continuous days. Left ventricular functions evaluated hemodynamic echocardiographic parameters. Results Metabolic rats had thicker interventricular septum left posterior wall, accompanied higher E/A wave...