Alix C. Thomson

ORCID: 0000-0003-3441-9291
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About
Contact & Profiles
Research Areas
  • Transcranial Magnetic Stimulation Studies
  • Neuroscience and Neural Engineering
  • Neurological disorders and treatments
  • Neural dynamics and brain function
  • Neural and Behavioral Psychology Studies
  • Muscle activation and electromyography studies
  • Functional Brain Connectivity Studies
  • Visual perception and processing mechanisms
  • Infrared Target Detection Methodologies
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Neurogenesis and neuroplasticity mechanisms
  • Pain Management and Treatment
  • Motor Control and Adaptation
  • Virus-based gene therapy research
  • Nuclear Receptors and Signaling
  • Pluripotent Stem Cells Research
  • Advanced MRI Techniques and Applications
  • Genetics and Neurodevelopmental Disorders
  • Nerve injury and regeneration
  • Behavioral Health and Interventions

Maastricht University
2017-2021

Cambridge Cognition (United Kingdom)
2021

National Council for Scientific and Technological Development
2021

Maastricht University Medical Centre
2020-2021

OPINION article Front. Neurol., 05 November 2020Sec. Neurorehabilitation Volume 11 - 2020 | https://doi.org/10.3389/fneur.2020.599918

10.3389/fneur.2020.599918 article EN cc-by Frontiers in Neurology 2020-11-05

Transcranial Magnetic Stimulation (TMS) is a form of non-invasive brain stimulation, used to alter cortical excitability both in research and clinical applications. The intermittent continuous Theta Burst (iTBS cTBS) protocols have been shown induce opposite after-effects on human cortex excitability. Animal studies implicated synaptic plasticity mechanisms long-term potentiation (LTP, for iTBS) depression (LTD, cTBS). However, the neural basis TMS effects has not yet studied neuronal cells,...

10.3389/fnmol.2020.528396 article EN cc-by Frontiers in Molecular Neuroscience 2020-10-19

In recent years, the influence of alpha (7-13 Hz) phase on visual processing has received a lot attention. Magneto-/encephalography (M/EEG) studies showed that indexes excitability and task performance. Studies with transcranial alternating current stimulation (tACS) aim to modulate oscillations causally impact Here, we applied right occipital tACS (O2 location) assess functional role in series experiments. We presented stimuli at different pre-determined, experimentally controlled, phases...

10.1111/ejn.14677 article EN cc-by-nc-nd European Journal of Neuroscience 2020-01-14

The rapid evolution of neuromodulation techniques includes an increasing amount research into stimulation paradigms that are guided by patients' neurophysiology, to increase efficacy and responder rates. Treatment personalisation target engagement have shown be effective in fields such as Parkinson's disease, closed-loop been successfully implemented cardiac defibrillators. Promising avenues being explored for physiologically informed psychiatry. Matching the frequency individual brain...

10.1016/j.jns.2021.120121 article EN cc-by Journal of the Neurological Sciences 2021-12-28

Despite the widespread use of SH-SY5Y human neuroblastoma cell line in modeling neurons vitro, protocols for growth, differentiation and experimentation differ considerably across literature. Many studies fully differentiate cells before experimentation, to investigate plasticity measures a mature, neuronal-like model. Prior serum is often removed from culture media, arrest growth cycle synchronize cells. However, exact effect this removal on differentiated has not yet been described. In...

10.1007/s10571-021-01062-x article EN cc-by Cellular and Molecular Neurobiology 2021-03-03

Cognitive effort and self-control are exhausting. Although evidence is ambiguous, behavioural studies have repeatedly suggested that control-demanding tasks seem to deplete a limited cache of self-regulatory resources leading performance degradations fatigue. While resource depletion has indirectly been associated with decline in right prefrontal cortex capacity, its precise neural underpinnings not yet revealed. This study consisted two independent experiments, which set out investigate the...

10.1371/journal.pone.0174331 article EN cc-by PLoS ONE 2017-03-31

Abstract In recent years the influence of alpha (7-13 Hz) phase on visual processing has received a lot attention. Magneto-/encephalography (M/EEG) studies showed that indexes excitability and task performance. If occipital is functionally relevant, alpha-frequency transcranial alternating current stimulation (tACS) could modulate processing. Visual stimuli presented at different pre-determined, experimentally controlled, phases entraining tACS signal should then result in an oscillatory...

10.1101/675264 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-06-20

Abstract Repetitive Transcranial Magnetic Stimulation (rTMS) is an established neuromodulation technique, using electromagnetic pulses that, depending on the precise parameters, a re assumed to lead lasting neural excitability changes. rTMS has widespread applications in both research and therapy, where it been FDA approved considered first-line treatment for depression, according recent North American European guidelines. However, these effects are often difficult replicate, highly...

10.1101/2020.08.19.257295 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-08-20
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