Juan Miguel Antón Santos

ORCID: 0000-0003-3443-1100
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 and healthcare impacts
  • COVID-19 diagnosis using AI
  • COVID-19 and Mental Health
  • Respiratory Support and Mechanisms
  • Intensive Care Unit Cognitive Disorders
  • Ultrasound in Clinical Applications
  • Sepsis Diagnosis and Treatment
  • Radiation Dose and Imaging
  • Machine Learning in Healthcare
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Systemic Sclerosis and Related Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Ethics and bioethics in healthcare
  • Radiomics and Machine Learning in Medical Imaging
  • Vector-Borne Animal Diseases
  • Clinical Reasoning and Diagnostic Skills
  • Nosocomial Infections in ICU
  • Public Health and Environmental Issues
  • Systemic Lupus Erythematosus Research
  • Antibiotic Use and Resistance
  • Otitis Media and Relapsing Polychondritis
  • Vascular Anomalies and Treatments

Hospital Universitario Infanta Cristina
2012-2025

Universidad Complutense de Madrid
2012-2023

Instituto de Investigación Sanitaria de Santiago
2023

To determine the proportion of patients with COVID-19 who were readmitted to hospital and most common causes factors associated readmission. Multicenter nationwide cohort study in Spain. Patients included admitted 147 hospitals from March 1 April 30, 2020. Readmission was defined as a new admission during 30 days after discharge. Emergency department visits discharge not considered During period 8392 participating SEMI-COVID-19 network. 298 (4.2%) out 7137 being discharged. 1541 (17.7%) died...

10.1038/s41598-021-93076-0 article EN cc-by Scientific Reports 2021-07-02

ABSTRACT Background Spain has been one of the countries most affected by COVID-19 pandemic. Objective To create a registry patients with hospitalized in order to improve our knowledge clinical, diagnostic, therapeutic, and prognostic aspects this disease. Methods A multicentre retrospective cohort study, including consecutive confirmed throughout Spain. Epidemiological clinical data, additional tests at admission seven days, treatments administered, progress 30 days hospitalization were...

10.1101/2020.05.24.20111971 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-05-26

Objectives: A decrease in blood cell counts, especially lymphocytes and eosinophils, has been described patients with serious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), but there is no knowledge of their potential role the recovery these patients’ prognosis. This article aims to analyse effect depletion on mortality due COVID-19. Design: work was a retrospective, multicentre cohort study 9644 hospitalised confirmed COVID-19 from Spanish Society Internal Medicine’s...

10.3390/jcm10020305 article EN Journal of Clinical Medicine 2021-01-15

The aim of this study was to analyze whether the coronavirus disease 2019 (COVID-19) vaccine reduces mortality in patients with moderate or severe COVID-19 requiring oxygen therapy. A retrospective cohort study, data from 148 hospitals both Spain (111 hospitals) and Argentina (37 hospitals), conducted. We evaluated hospitalized for older than 18 years requirements. Vaccine protection against death assessed through a multivariable logistic regression propensity score matching. also performed...

10.1002/jmv.28786 article EN cc-by-nc-nd Journal of Medical Virology 2023-05-01

The aim of this study was to analyze whether subgroups immunosuppressive (IS) medications conferred different outcomes in COVID-19.The involved a multicenter retrospective cohort consecutive immunosuppressed patients (ISPs) hospitalized with COVID-19 from March July, 2020. primary outcome in-hospital mortality. A propensity score-matched (PSM) model comparing ISP and non-ISP planned, as well specific PSM models individual IS associated mortality.Out 16 647 patients, 868 (5.2%) were on...

10.1016/j.ijid.2021.12.327 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-12-28

Venous thrombotic events (VTE) are frequent in COVID-19, and elevated plasma D-dimer (pDd) dyspnea common both entities. To determine the admission pDd cut-off value associated with in-hospital VTE patients COVID-19. Multicenter, retrospective study analyzing at-admission to predict anticoagulation intensity along hospitalization due Among 9386 patients, 2.2% had VTE: 1.6% pulmonary embolism (PE), 0.4% deep vein thrombosis (DVT), 0.2% both. Those a higher prevalence of tachypnea (42.9% vs....

10.1007/s11606-021-07017-8 article EN other-oa Journal of General Internal Medicine 2021-07-21

Background The individual influence of a variety comorbidities on COVID-19 patient outcomes has already been analyzed in previous works an isolated way. We aim to determine if different associations diseases the inpatients with COVID-19.Methods Retrospective cohort multicenter study based clinical practice. Data were taken from SEMI-COVID-19 Registry, which includes most consecutive patients confirmed hospitalized and discharged Spain. Two machine learning algorithms applied order classify...

10.1080/03007995.2022.2029382 article EN Current Medical Research and Opinion 2022-01-17

New SARS-CoV-2 variants, breakthrough infections, waning immunity, and sub-optimal vaccination rates account for surges of hospitalizations deaths. There is an urgent need clinically valuable generalizable triage tools assisting the allocation hospital resources, particularly in resource-limited countries. We developed validate CODOP, a machine learning-based tool predicting clinical outcome hospitalized COVID-19 patients. CODOP was trained, tested validated with six cohorts encompassing...

10.7554/elife.75985 article EN cc-by eLife 2022-05-17

The emergence of new SARS-CoV-2 variants with significant immune-evasiveness, the relaxation measures for reducing number infections, waning immune protection (particularly in high-risk population groups), and low uptake vaccine boosters, forecast waves hospitalizations admission to intensive care units. There is an urgent need easily implementable clinically effective Early Warning Scores (EWSs) that can predict risk complications within next 24-48 hr. Although EWSs have been used...

10.7554/elife.85618 article EN cc-by eLife 2023-08-24
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