- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Epilepsy research and treatment
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Music Perception
- Neonatal and fetal brain pathology
- Medical Imaging Techniques and Applications
- Hearing Loss and Rehabilitation
- Olfactory and Sensory Function Studies
- Neural and Behavioral Psychology Studies
- Infant Health and Development
- Music Therapy and Health
- Attention Deficit Hyperactivity Disorder
- Memory and Neural Mechanisms
- Biochemical Analysis and Sensing Techniques
- Blind Source Separation Techniques
- Advanced Chemical Sensor Technologies
- Infant Development and Preterm Care
- Fetal and Pediatric Neurological Disorders
- Diabetic Foot Ulcer Assessment and Management
- Geomagnetism and Paleomagnetism Studies
University of Geneva
2016-2025
Sciences Cognitives et Sciences Affectives
2023
Laboratoire d’Imagerie Biomédicale
2023
Centre d'Imagerie BioMedicale
2014-2023
University Hospital of Geneva
2012-2021
Hôpital Beau-Séjour
2021
Geneva College
2014
Grenoble Institute of Neurosciences
2007-2010
Inserm
2007-2010
Université Joseph Fourier
2007-2010
In patients with medically refractory focal epilepsy who are candidates for surgery, concordant non-invasive neuroimaging data useful to guide invasive electroencephalographic recordings or surgical resection. Simultaneous electroencephalography and functional magnetic resonance imaging can reveal regions of haemodynamic fluctuations related epileptic activity help localize its generators. However, many these studies (40–70%) remain inconclusive, principally due the absence interictal...
Significance Preterm babies are cared for in neonatal intensive care units (NICU), which busy places with a lot of mechanical noise increasingly recognized to disrupt normal brain development. NICUs therefore invest developmental procedures, music example, but neurobiological evidence these interventions is missing. We present results from clinical trial study the effects intervention on preterm infants’ Based resting-state fMRI, we provide that enhanced connectivity circuitry involving...
Drug-resistant temporal lobe epilepsy (TLE) often requires thorough investigation to define the epileptogenic zone for surgical treatment. We used simultaneous interictal scalp EEG-fMRI evaluate its value predicting long-term postsurgical outcome.30 patients undergoing presurgical evaluation and proceeding (TL) resection were studied. Interictal epileptiform discharges (IEDs) identified on intra-MRI EEG build a model of haemodynamic changes. In addition, topographic electroencephalographic...
Neonatal Intensive Care Units (NICU) provide special equipment designed to give life support for the increasing number of prematurely born infants and assure their survival. More recently NICU's strive include developmentally oriented care modulate sensory input preterm infants. Music, among other stimuli, has been introduced into NICUs, but without knowledge on basic music processing in brain In this study, we explored cortico-subcortical different types conditions (Original music, Tempo...
Recent data suggest that musical practice prevents age-related cognitive decline. But experimental evidence remains sparse and no concise information on the neurophysiological bases exists, although decline represents a major impediment to healthy aging. A challenge in field of aging is developing training regimens stimulate neuroplasticity delay or reverse symptoms cerebral To be successful, these should easily integrated daily life intrinsically motivating. This study combines for...
Both electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) are non-invasive methods that show complementary aspects of human brain activity. Despite measuring different proxies activity, both the measured blood-oxygenation neurophysiological recordings indirectly coupled. The electrophysiological BOLD signal can map underlying connectivity structure at whole scale timescales. Previous work demonstrated a moderate but significant correlation between resting-state...
While aging is characterized by neurodegeneration, musical training associated with experience-driven brain plasticity and protection against age-related cognitive decline. However, evidence for the positive effects of mostly comes from cross-sectional studies while randomized controlled trials larger sample sizes are rare. The current study compares influence six months piano music listening/musical culture lessons in 121 musically naïve healthy elderly individuals regard to white matter...
Summary Purpose: In the presurgical evaluation of children and juvenile patients with refractory focal epilepsy, main challenge is to localize point seizure onset as precisely possible. We compared results conventional electroencephalography–functional magnetic resonance imaging (EEG‐fMRI) analysis those obtained a newly developed method using voltage maps average interictal epileptiform discharges (IEDs) recorded during clinical long‐term monitoring electric source (ESI). Methods:...
Surgical treatment in epilepsy is effective if the epileptogenic zone (EZ) can be correctly localized and characterized. Here we use simultaneous electroencephalography-functional magnetic resonance imaging (EEG-fMRI) data to derive EEG-fMRI electrical source (ESI) maps. Their yield their individual combined ability (1) localize EZ (2) predict seizure outcome were then evaluated.Fifty-three children with drug-resistant underwent EEG-fMRI. Interictal discharges mapped using both hemodynamic...
Summary Objective Epilepsy is increasingly considered as the dysfunction of a pathologic neuronal network (epileptic network) rather than single focal source. We aimed to assess interactions between regions that comprise epileptic and investigate their dependence on occurrence interictal epileptiform discharges ( IED s). Methods analyzed resting state simultaneous electroencephalography–functional magnetic resonance imaging EEG ‐ fMRI ) recordings in 10 patients with drug‐resistant epilepsy...
Simultaneous electroencephalography and functional magnetic resonance imaging (EEG/fMRI) have been proposed to contribute the definition of epileptic seizure onset zone. Following interictal epileptiform discharges, one usually assumes a canonical hemodynamic response function (HRF), which has derived from fMRI studies in healthy subjects. However, recent findings suggest that properties brain are likely differ significantly physiological responses. Here, we propose simple robust approach...