- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet and metabolism studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer, Hypoxia, and Metabolism
- Adrenal Hormones and Disorders
- Thyroid Disorders and Treatments
- Diabetes Management and Research
- Chronic Disease Management Strategies
- Diabetes Treatment and Management
- Muscle and Compartmental Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Gut microbiota and health
- Neuroendocrine Tumor Research Advances
- Retinal Imaging and Analysis
- Hedgehog Signaling Pathway Studies
- Diabetes Management and Education
- Retinal Diseases and Treatments
- Myasthenia Gravis and Thymoma
- Chronic Kidney Disease and Diabetes
- Vitamin D Research Studies
- Obesity and Health Practices
- Cardiovascular Health and Risk Factors
- Hormonal Regulation and Hypertension
- Chronic Myeloid Leukemia Treatments
- Pancreatic function and diabetes
Tsinghua University
2020-2024
Beijing Tsinghua Chang Gung Hospital
2020-2024
Diabetes Australia
2021
Weatherford College
2021
Jacksonville College
2020
Mayo Clinic in Florida
2020
Diabetic kidney disease (DKD) and diabetic retinopathy (DR) share similar pathophysiological mechanisms. However, signs of DKD may be present at diagnosis diabetes without retinopathy. Risk factors for the development DR not identical.This study aimed to evaluate concordance discordance between by investigating distribution in patients with type 2 mellitus from 5 Chinese cities. A total 26,809 were involved this study. The clinical characteristics compared among based on presence DR....
Obesity has become a major public health concern worldwide, increasing the risk of T2DM. Growing evidence indicates gut microbiota dysbiosis is related to metabolic disorders. We aimed firstly investigate compositional and functional features microbiome between obesity with without T2DM in Chinese population.
The activation of immune cells plays a significant role in the progression type 2 diabetes. This study aimed to investigate potential myeloid-derived suppressor (MDSCs) and T-regulatory (Tregs) diabetes.A total 61 patients diagnosed with diabetes were recruited. Clinical characteristics reviewed peripheral blood samples collected. We calculated percentage different cells. Frequencies MDSC subsets refered G-MDSCs (CD15+CD33+CD11b+CD14-HLA-DR-/low) CD45 positive M-MDSCs...
Background Pituitary stalk interruption syndrome (PSIS) is a congenital disease commonly found in patients with combined pituitary hormone deficiency (CPHD). Most PSIS manifest growth retardation and delayed puberty. We report rare case of tall stature, liver cirrhosis diabetes, possibly caused by an inactivating KCNJ11 gene mutation. Case presentation A 37-year-old female patient initially presented without any secondary sexual characteristics. Endocrine investigation indicated CPHD. Small...
Trial design: Our study is to investigate the feasibility and effectiveness of multiple cardiovascular factors intervention (MFI) in type 2 diabetes patients China’s primary care setting. Methods: We performed a cluster randomized trial compare proportion achieved targets between usual group (control, 9 sites, n = 868) MFI (8 739) among with Logistic regression model random effects was used estimate association effect targets. Results: At baseline, end 1 year, years follow-up, all 3 target...
Von Hippel-Lindau (VHL) syndrome is characterized by tumorous lesions affecting multiple organs. Pancreatic involvement in VHL can present as endocrine tumors and pancreatic cysts, which interfere with both exocrine functions of the pancreas. Diabetes an uncommon complication syndrome.
Key Clinical Message Acute chest pain can be the first manifestation of multiple endocrine neoplasia type 1(MEN1)‐associated thymic neuroendocrine neoplasms (NEN). Comprehensive treatment may an effective strategy for MEN1‐associated NEN. Abstract Multiple (NEN) is caused by mutation tumor suppressor MEN1 gene. Patients with NEN initially presenting acute are very rare. In manuscript, we reported a case 45‐year‐old man who developed as initial symptom. Thoracoscopic thymotomy was performed...
Primary hyperaldosteronism with type 3 autoimmune polyendocrine syndrome was a rare combination of both hyper- and hypoendocrine gland function. Comprehensive treatment including surgery replacement therapy might be an effective strategy.
To evaluate the atherosclerotic cardiovascular diseases (ASCVD) risk factors in type 2 diabetes patients from primary clinics for further comprehensive intervention China.A cross-sectional study was conducted 5 chain hospitals Beijing, Lanzhou, Harbin, Chengdu, and Taiyuan continuous with March 2016 to December 2019. The data collected at first visit were analyzed, proportions of reached targets (glycosylated hemoglobin [HbA1c] < 7%, blood pressure 130/80 mm Hg, low-density lipoprotein...
Abstract BACKGROUND At the initial presentation of autoimmune adrenal insufficiency, most patients present with hormonal deficiencies from all three layers cortex. However, isolated aldosterone deficiency causing a true partial insufficiency in setting adrenalitis remains underrecognized. CASE REPORT A 67-year old female patient known history diabetes mellitus type 1 since age 13 and morphea, presented progressively worsening symptoms confusion hallucinations, fatigue, loss appetite over...
Abstract Background: Maturity onset diabetes in young 3 (MODY 3) is caused by mutation of the hepatic nuclear factor 1 alpha (HNF-1A) gene. Craniofacial macrosomia (CFM) associated with an abnormal development craniofacial structures during embryonic period. Maternal and genetic predisposition have been CFM1. There are rare reports about association MODY CFM. Clinical case: An 11-year-old male patient presented right side CFM (mild mandibular hypoplasia, internal auditory canal absence,...
OBJECTIVE Hospital hyperglycemia is common and associated with potential adverse outcomes. A Hospital-wide Mobile Phone Alert (HMA) system was built to achieve real time glucose monitoring warnings for excursions. This study investigated the status of control evaluated impact HMA on inpatient glycemia management. METHODS Inpatients hospitalized between 1 January, 2017 31 December, 2018 were identified excluding those < 18 years age. The activated October, 2017. It sent cellphone warning...
Abstract Aim:To evaluate the atherosclerotic cardiovascular diseases (ASCVD) risk factors in type 2 diabetes (T2DM) patients from primary clinics for further comprehensive intervention China.Methods:A cross-sectional study was conducted 5 chain hospitals Beijing, Lanzhou, Harbin, Chengdu and Taiyuan continuous with T2DM March 2016 to December 2019. The data collected at first visit were analyzed, proportions of reached targets (glycosylated hemoglobin (HbA 1C ) < 7%, blood pressure 130 /...
BACKGROUND Hospital hyperglycemia is common and associated with potential adverse outcomes. A Hospital-wide Mobile Phone Alert (HMA) system was built to achieve real time glucose monitoring warnings for excursions. This study investigated the status of control evaluated impact HMA on inpatient glycemia management. METHODS Inpatients hospitalized between 1 January, 2017 31 December, 2018 were identified excluding those < 18 years age. The activated October, 2017. It sent cellphone warning...