A5069544763- Natural product bioactivities and synthesis
- Nanoparticles: synthesis and applications
- Essential Oils and Antimicrobial Activity
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Phytochemicals and Antioxidant Activities
- Curcumin's Biomedical Applications
- Synthesis and biological activity
- Pharmacological Effects of Natural Compounds
- Bioactive Compounds and Antitumor Agents
- Phytochemical compounds biological activities
- Moringa oleifera research and applications
- Cancer-related Molecular Pathways
- Tannin, Tannase and Anticancer Activities
- MicroRNA in disease regulation
- Piperaceae Chemical and Biological Studies
- Cancer, Hypoxia, and Metabolism
- Graphene and Nanomaterials Applications
- Cell death mechanisms and regulation
- Computational Drug Discovery Methods
- Diabetes Treatment and Management
- Coagulation and Flocculation Studies
- Nanoparticle-Based Drug Delivery
- Genomics, phytochemicals, and oxidative stress
Saveetha University
2024-2025
Jaypee Institute of Information Technology
2019-2024
Quaid-e-Awam University of Engineering, Science and Technology
2024
Lady Reading Hospital
2024
Institute of Engineering
2020-2024
King Fahd University of Petroleum and Minerals
2024
James Cook University Hospital
2023
Northeast Georgia Medical Center
2022
Hazara University
2022
Brooklyn Hospital Center
2021
Cancer has become one of the most multifaceted and widespread illnesses affecting human health, causing substantial mortality at an alarming rate. After cardiovascular problems, condition a high occurrence rate ranks second in terms mortality. The development new drugs been facilitated by increased research deeper understanding mechanisms behind emergence advancement disease. Numerous preclinical clinical studies have repeatedly demonstrated protective effects natural terpenoids against...
Andrographolide, a diterpenoid lactone and major constituent of Andrographis paniculata Nees, exhibits remarkable anticancer activity. However, the effect andrographolide on colon cancer has not been completely elucidated yet. Thus, we investigated chemopreventive potential in HT-29 cells. The cytotoxic cells was determined by MTT assay, trypan blue exclusion colony formation morphological analysis; apoptotic property DAPI Hoechst staining, FITC-Annexin V DNA fragmentation assay caspase-3...
Carvacrol, a major monoterpenoid phenol from Origanum and Thymus species, has been shown to exhibit antiproliferative anticancer properties in few recent studies. Nevertheless, detailed mechanism of the action this compound prostate cancer not elucidated yet. Therefore, current study, we examined activity carvacrol against human cells. It was found that treatment DU145 cells with decreased cell viability concentration time-dependent manner. The leads induction apoptosis as confirmed by...
Several studies have revealed that abnormal activation of Notch signaling is closely related with the development and progression prostate cancer. Although there are numerous therapeutic strategies, a more effective modality least side effects urgently required for treatment Carvacrol monoterpenoid phenol majorly present in essential oils Lamiaceae family plants. Many previous reports shown various biological activities carvacrol like antioxidant, antiinflammatory anticancer properties....
Sustainable agriculture is crucial for stimulating both developing and developed countries. Agriculture needs modernization innovation to meet the increasing demands of food growing global population maintain environmental sustainability simultaneously. Nanotechnology has gained wider attention in safety improvement environment protection by augmenting efficacy agricultural inputs giving potent solutions issues improving security productivity. Modern practices have been found be associated...
Liver cancer is the second leading cause of cancer-related death worldwide. However, treatment options, including surgical resection, transplantation, and molecular drug therapies, are limited effectiveness. Recent studies have demonstrated that suppressing ferroptosis might be a pivotal signal for liver initiation, thus providing new way to combat cancer. Ferroptosis distinct form controlled cell differs from conventional routes like apoptosis, necrosis, pyroptosis. It results intracellular...
Cervical cancer is the fourth most common among women worldwide and a major cause of morbidity mortality. High-risk Human Papilloma Virus (mostly type 16 & 18) infection primary risk factor for development cervical carcinoma. The quest strong, safe cost effective natural antiproliferative agents that could reduce have been focussed now day. Recently, glycyrrhizin, triterpene glycoside (saponin) from licorice (Glycyrrhiza glabra Linn.), has shown to exhibit potent anticancer properties in few...
The infection of the global COVID-19 pandemic and absence any possible treatment options warrants use all available resources to find effective drugs against this scourge. Various ongoing researches have been searching for new drug candidate infection. research objective is based on molecular docking study inhibition main protease by natural compounds found in Allium sativum cepa. Lipinski rule five Autodock 4.2 was used using Lamarckian Genetic Algorithm perform Molecular analyze...
Chitin is a major structural polysaccharide after cellulose and exists as the most abundant polymer in nature. nitrogen-containing homopolymer of β-(1,4) linked N-Acetylglucosamine. It key cell wall component fungi, also found wide range organisms, including viruses, plants, animals, insect exoskeletons, crustacean shells. This review focused on recent developments applications chitin, chitinases, chitin derivatives biomedicinal, agricultural environmental perspectives for sustainable...
Ferroptosis, a novel form of regulated cell death characterized by dependence on iron and lipid peroxidation, has been implicated in wide range clinical conditions including neurological diseases, cardiovascular disorders, acute kidney failure, various types cancer. Therefore, it is critical to suppress cancer progression proliferation. Ferroptosis can be triggered cells some normal synthetic substances, such as erastin, Ras-selective lethal small molecule-3, or pharmaceuticals. Natural...
Lipids, the primary constituents of cell membrane, play essential roles in nearly all cellular functions, such as cell-cell recognition, signaling transduction, and energy provision. Lipid metabolism is necessary for maintenance life since it regulates balance between processes synthesis breakdown. Increasing evidence suggests that cancer cells exhibit abnormal lipid metabolism, significantly affecting their malignant characteristics, including self-renewal, differentiation, invasion,...