A5057069284- Infection Control and Ventilation
- Indoor Air Quality and Microbial Exposure
- Building Energy and Comfort Optimization
- Reconstructive Facial Surgery Techniques
- Skin Protection and Aging
- Rocket and propulsion systems research
- COVID-19 and healthcare impacts
- Food Security and Health in Diverse Populations
- Fish Ecology and Management Studies
- Fish Biology and Ecology Studies
- SARS-CoV-2 and COVID-19 Research
- Urban Heat Island Mitigation
- Thermal Regulation in Medicine
- Advanced Aircraft Design and Technologies
- Reconstructive Surgery and Microvascular Techniques
- Legionella and Acanthamoeba research
- Mechanisms of cancer metastasis
- Cancer Mechanisms and Therapy
- Noise Effects and Management
- Psoriasis: Treatment and Pathogenesis
- Travel-related health issues
- Medical Device Sterilization and Disinfection
- Sleep and Work-Related Fatigue
- Advanced Combustion Engine Technologies
- Zoonotic diseases and public health
Icahn School of Medicine at Mount Sinai
2012-2025
Johnson & Johnson (Israel)
2024
Synairgen (United Kingdom)
2024
Rensselaer Polytechnic Institute
2024
Mount Sinai Medical Center
2023
Mount Sinai Hospital
2021
University of Maryland, Baltimore
2016-2020
Logan Hospital
2019
Mount Sinai Hospital
2018
University of Mary
2017
Objectives. We evaluated the safety of room occupants in Tuberculosis Ultraviolet Shelter Study (TUSS), a double-blind, placebo-controlled field trial upper-room ultraviolet germicidal irradiation (UVGI) at 14 homeless shelters six U.S. cities from 1997 to 2004. Methods. Data collection involved administering questionnaires regarding eye and skin irritation total 3,611 staff study subjects. Results. Among these subjects, there were 223 reports or symptoms. During active UV period, 95 (6%)...
Bioterrorism is an area of increasing public health concern.The intent this article to review the air cleansing technologies available protect building occupants from intentional release bioterror agents into congregate spaces (such as offices, schools, auditoriums, and transportation centers), well through outside intakes by way recirculation ducts.Current include increased ventilation, filtration, ultraviolet germicidal irradiation (UVGI) UVGI a common tool in laboratories care facilities,...
ABSTRACT Poor sleep is common in hospitalised patients due to multiple factors, including disruption of the circadian rhythm. Few studies have examined programmable artificial lighting systems hospital patient rooms, and few achieved meaningful improvement sleep. We sought determine how novel dynamic affects timing duration compared standard lighting. Patients were admitted rooms on a cardiology unit with customised intervention or The system delivered blue‐enriched light during day,...
Abstract Background Bioaerosol-mediated transmission of COVID-19 via building ventilation systems has yet to be convincingly demonstrated. We used the South African Airborne Infections Research (AIR) facility near Pretoria study human animal (H2A) SARS-CoV-2 in newly diagnosed patients. While was built tuberculosis transmission, this its first adaptation H2A virus transmission. Methods Clinically confirmed patients were housed for up four days AIR with continuously exhausting patient ward...
The objective of this research was to study the factors that relate effectiveness upper-room ultraviolet germicidal irradiation for inactivating airborne microorganisms. work conducted in a room-sized chamber designed and furnished investigations nature. Nebulized Serratia marcescens, Bacillus subtilis spores, vaccinia virus were used as test aerosols. Most data collected from steady-state experiments comparing number viable organisms air remaining with UV lamps turned on off, but some decay...
(1971). River Electrofishing and Fish Population Estimates. The Progressive Fish-Culturist: Vol. 33, No. 3, pp. 163-169.
Conductive hearing loss due to ossicular abnormalities occurs from many causes, including trauma, infection, cholesteatoma, surgery and congenital anomalies. Surgical reconstruction of the chain is a well-established procedure for repair defects, but still plagued by high failure rates. Underlying disease proper sizing prostheses are two challenges that lead component failure. Three-dimensional (3D) printing has been used successfully solve number medical prosthesis problems. Custom 3D an...
Abstract This study investigated the disinfection efficacy of upper‐room ultraviolet germicidal irradiation ( UR ‐ UVGI ) system with ceiling fans. The investigation used steady‐state computational fluid dynamics CFD simulations to solve rotation fan a rotating reference frame. Two ambient air exchange rates, 2 and 6 changes per hour (ACH), four downward rotational speeds, 0, 80, 150 235 rpm were considered. In addition, passive scalar concentration incorporated UV dose by two methods: one...
Abstract Particulate respirators such as N95s are an essential component of personal protective equipment (PPE) for front-line workers. This study describes a rapid and effective UVC irradiation system that would facilitate the safe re-use N95 provides supporting information deploying decontamination SARS-CoV-2 during COVID-19 pandemic. To assess inactivation potential proposed germicidal device function time by using 3 M 8211-N95 particulate inoculated with SARS-CoV-2. A to deliver tailored...
Abstract A commercial computer-aided design tool used by the lighting industry was modified to predict fluence rates for upper-room ultraviolet germicidal irradiation. Experimental validation based on more than 1600 measurements and 3 types of fixtures, which done in an experimental chamber a homeless shelter having fixtures continuous use over 7 years, showed differences measured predicted average less 10%. The tool, however, not very successful at predicting specific room locations,...
Upper-room ultraviolet germicidal irradiation (UVGI) has several applications, its most important use is to reduce tuberculosis transmission in high-burden, resource-limited settings, especially those dealing with epidemics of drug-resistant disease. The efficacy upper-room the airborne infection real-world settings no longer question. International application (dosing) guidelines are needed, as safety standards and commissioning procedures. A recent symposium build consensus on discussed...
We conducted a retrospective study to examine trends in latent tuberculosis infection (LTBI) and TB disease rates among homeless persons shelters New York, NY, 1992-2006. Although case fell from 1,502/100,000 population 0, 31% LTBI rate 2006 shows the value of identifying treating homeless.
Abstract Importance Particulate respirators such as N95 masks are an essential component of personal protective equipment (PPE) for front-line workers. This study describes a rapid and effective UVC irradiation system that would facilitate the safe re-use provides supporting information deploying decontamination SARS-CoV-2 during COVID19 pandemic. Objective To assess inactivation potential proposed germicidal device function time by using 3M® 8211 - particulate inoculated with SARS-CoV-2....
Abstract This paper reports results from a field study designed to demonstrate method for evaluating building's in-duct ultraviolet germicidal irradiation (UVGI) system using naturally occurring airborne microorganisms and evaluate its potential effectiveness against selected microorganisms. Forty-eight 64 in. (1.63 m) long lamps were installed perpendicular airflow upstream of the cooling coils in heating, ventilating, air-conditioning (HVAC) retail space large New York City office...
Abstract Several tests evaluated the whirling disease resistance of three stocks rainbow trout Oncorhynchus mykiss: Fish Lake–DeSmet (FD), Wounded Man (WM), and Harrison Lake (HL) strains. In one series, FD fish were exposed to Myxobolus cerebralis triactinomyxons (TAMs; exposure 1,000 TAMs/fish). Histological scores ranged from 4.28 4.95 (MacConnnell−Baldwin scale) among different hatcheries. addition, either acutely (1,000 TAMs/fish in dose) or chronically (100 200 on each 10 d). There was...
Concerns about the safety of Ultraviolet Germicidal Irradiation (UVGI) applications on human beings have been an issue at least since introduction this technology for practical use in 1930s. The resurgence tuberculosis (TB) United States mid-1980s led to a revival interest UV technology, focus that had almost disappeared because alternate means controlling TB inaccurately deemed successful. These failures control UVGI use. And with grew necessary and appropriate concerns attempts eliminate...
Reduced NME1 expression in melanoma cell lines, mouse models of melanoma, and specimens human patients is associated with increased metastatic activity. Herein, we investigate the role repair double-stranded breaks (DSBs) choice double-strand break (DSBR) pathways cells. Using chromatin immunoprecipitation, was shown to be recruited rapidly directly DSBs generated by homing endonuclease I-PpoI. within 30 min, concert recruitment ataxia-telangiectasia mutated (ATM) protein, an early step DSBR...
Mobile whole-room UVGI devices are used in healthcare settings to control surface-borne pathogens. Unfortunately, no standard method comparing the efficacy of these is available. We accessed effect shadows on UVC 254 nm inactivation. The evaluation a mobile device spores Bacillus atrophaeus as surrogate for Clostridium difficile and Staphylococcus aureus MSRA. Inactivation after 10 min exposure varied significantly depending whether received direct UV (4.3 log reduction), both reflected...