A5100334030- Glioma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Pituitary Gland Disorders and Treatments
- Acute Ischemic Stroke Management
- Adrenal and Paraganglionic Tumors
- Neurofibromatosis and Schwannoma Cases
- Esophageal Cancer Research and Treatment
- Sarcoma Diagnosis and Treatment
- Immune cells in cancer
- Meningioma and schwannoma management
- Spinal Dysraphism and Malformations
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Cardiac tumors and thrombi
- Soft tissue tumor case studies
- Cancer Immunotherapy and Biomarkers
- Hemoglobinopathies and Related Disorders
- Plant Ecology and Soil Science
- Retinal and Macular Surgery
- Spinal Hematomas and Complications
- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Fluoride Effects and Removal
- Vascular Malformations Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
Yangzhou University
2025
Zhengzhou University
2024
Affiliated Hospital of Taishan Medical University
2023
Shandong First Medical University
2023
Sichuan University
2022
West China Hospital of Sichuan University
2022
First Affiliated Hospital of Zhengzhou University
2017-2021
Zhongda Hospital Southeast University
2016
Virginia Tech
2014
Shanxi Medical University
2012
Abstract Intracerebral hemorrhage (ICH) remains a devastating type of stroke that lacks an effective treatment. Recent evidence has demonstrated CCL2 is involved in the blood‐brain barrier (BBB) disruption and propagermanium (PG) as receptor inhibitor neuroprotective ischemic stroke. However, whether PG therapy exert role acute ICH still unclear. In this study, our goal was to investigate potential effects ICH. Differentially expressed RNAs including were detected human activation p‐p38 MAPK...
Disruption of the blood-brain barrier (BBB) and subsequent neurological deficits are most severe consequence intracerebral hemorrhage (ICH). Minocycline has been wildly used clinically as a protective agent in clinical practice. However, underlying mechanisms by which minocycline functions remain unclear. Therefore, we assessed influence on BBB structure, function, inflammatory responses collagenase-induced ICH model, elucidated molecular well. Following single injection collagenase VII-S...
Abstract Background Intracerebral hemorrhage (ICH) is a catastrophic cerebrovascular disease with high morbidity and mortality. Evidence demonstrated that sphingosine‐1‐phosphate receptor (S1PR) plays vital role in inflammatory damage via the upregulation of CCL2 expression. However, whether S1PR3 involved blood‐brain barrier (BBB) breakdown activation after ICH has not been described. Methods We investigated expression profiles all S1PRs using high‐throughput RNA‐seq analysis RT‐PCR. The...
Pituitary carcinomas (PCs) is considerable uncommon entities with a poor prognosis that represents only 0.1-0.2% of all pituitary tumors. There are fewer than 150 reported cases up to now. In addition, the molecular pathogenesis leading malignant transformation remain unclear due rarity PCs. Here we present an case ACTH-secreting PCs and explore gene mutation following adenoma transformation. Our detailed clinical, histopathological detection data suggest novel genes ATRX PTEN were...
Rationale: Primary spinal primitive neuroectodermal tumors (PNETs) are highly malignant tumors, which extremely rare entities and primary intramedullary PNETs rare. Till now, only 24 cases of PNET have been reported. Patient concerns: A 26-year-old male presented with progressive low back lower limb pain for 1 month. Diagnoses: Based on MRI histopathological findings, he was diagnosed PNET. Interventions: The patient treated two times microsurgical resections. Outcomes: Follow-up visit at 14...
Upper esophageal gastric heterotopia (inlet patch) has not been reported in endoscopic series from China. We describe the occurrence of endoscopically and histologically typical inlet patches two surveys asymptomatic adults northern Because rapid protocols were used, 0.3-0.4% prevalence patch these probably represents a minimum figure for this population.
Abstract Background The posterior-inferior border of symphysis (PIBS) point system is a novel vaginal dose-reporting method and simple reliable proposed by the Medical University Vienna for both external-beam radiotherapy (EBRT) brachytherapy (BT). In this multicenter study, we sought to first evaluate radiation dose in Chinese cervical cancer patients according PIBS then analyze factors influencing distribution. Methods We collected data from medical records 936 who underwent concurrent...
To investigate the clinicopathological features and related factors affecting microsurgical resection of lesions in cavernous sinus.Clinical data 66 patients undergoing microsurgery for located sinus from January 2011 to December 2017 were retrospectively reviewed.Histopathological examination revealed benign 60 (90.9%) patients, most common histopathological types meningiomas, schwannomas, hemangiomas. Only six (9.1%) had malignant lesions. The gross total rate was 33%, subtotal 21%,...
Eosinophilic granulomatosis with polyangiitis (EGPA) is an extremely rare rheumatic immune disease characterized by vasculitis of small- and medium-sized blood vessels. Central nervous system (CNS) involvement frequently consists cerebrovascular disease; a manifestation multiple demyelinating lesions has never been reported in detail. This report describes 38-year-old man, who presented progressive memory deterioration underwent microsurgery; EGPA was subsequently confirmed. Unique clinical...