- Neurological disorders and treatments
- Transcranial Magnetic Stimulation Studies
- Epilepsy research and treatment
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Cardiac Arrhythmias and Treatments
- Urinary Bladder and Prostate Research
- Myasthenia Gravis and Thymoma
- EEG and Brain-Computer Interfaces
- Peripheral Neuropathies and Disorders
- Motor Control and Adaptation
- Cardiovascular and Diving-Related Complications
- Pharmacological Effects and Toxicity Studies
- Muscle activation and electromyography studies
- Neuroscience and Neuropharmacology Research
- Metabolism and Genetic Disorders
- Pain Mechanisms and Treatments
- Migraine and Headache Studies
- Neurological and metabolic disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Pain Management and Treatment
- Advanced Neuroimaging Techniques and Applications
- Atrial Fibrillation Management and Outcomes
- Infectious Encephalopathies and Encephalitis
St. Eugenio Hospital
2011-2025
Università Campus Bio-Medico
2020
Campus Bio Medico University Hospital
2020
University of Rome Tor Vergata
1993-2003
Istituti di Ricovero e Cura a Carattere Scientifico
2000
Fondazione Santa Lucia
1998
Istituto delle Scienze Neurologiche di Bologna
1997
Sapienza University of Rome
1990-1991
Johnson University
1987
Aripiprazole (AP), a dopamine (DA) D(2) receptor partial agonist, has recently been used to reduce schizophrenic symptoms, while tetrabenazine (TBZ), DA depletor, treat hyperkinesias in Huntington's disease (HD). The aim of this study is define the role AP on chorea, motor performance, and functional disability, compare effects vs. TBZ small six patients with HD. Both increased Unified Disease Rating Scale (UHDRS) chorea score similar way. However, caused less sedation sleepiness than was...
To compare acute and chronic effects of l-dopa on bladder function in levodopa-naive Parkinson disease (PD) patients who had urinary urgency.We evaluated 26 l-dopa-naive PD at a university-based center with first urodynamic session double examination: the off treatment condition 1 hour after challenge carbidopa/l-dopa 50/200 mg; then, monotherapy was administered (mean dose 300 +/- 150 mg). Two months later, underwent second single evaluation challenge.The significantly worsened overactivity...
Abstract Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized involuntary detrusor overactivity. We evaluated possible impact of a 2‐week course low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining disturbances. tested the effects rTMS measuring urodynamic examination and International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation...
Understanding pathogenetic background and risk factors is the primary step to a better behavioral psychological symptoms of dementia (BPSD) management. To this aim, exploratory study designed sketch some indicative correlations between BPSD severity vascular, genetic cognitive variables. A retrospective cross-sectional conducted on medical reports 135 Alzheimer Dementia (AD) patients from two memory clinics. Each subject underwent clinical examination brain Magnetic Resonance Imaging (MRI),...
<b><i>Objective:</i></b> To reverse the profile of abnormal intracortical excitability in patients with ALS by administering drugs that promote GABAergic transmission. <b><i>Background:</i></b> Transcranial magnetic stimulation (TMS) has revealed abnormalities cortical inhibition ALS, a reduction silent period, and absence normally occurring response to paired TMS. Impaired inhibitory transmission could play role physiopathology this illness. <b><i>Methods:</i></b> Using TMS conditioning...
The effect of dopamine agonists (DAs) on cognition in Parkinson's disease (PD) is not yet completely established. Previous papers reported a worsening some cognitive functions with DAs, but others, suggesting that DAs may differently affect PD patients according to their pharmacological characteristics. We set out test the rotigotine and cabergoline group forty non-demented early-mild (H Y at same time, motor function was monitored under three different treatment conditions: DA (rotigotine...
In Parkinson's disease (PD) the urinary dysfunction manifests primarily with symptoms of overactive bladder (OAB). The OAB questionnaire (OAB-q) is a measure designed to assess impact on health-related quality life. this study, we quantified in large cohort PD patients by using OAB-q short form. Possible correlations between and clinical features were tested. Three hundred two enrolled study. Correlations sex, age, Unified Disease Rating Scale part III (UPDRS-III), Hoehn-Yahr (H-Y) staging,...
The aim of this study is to provide neurophysiologic evidence ipsilateral hemispheric activation in patients affected by intracerebral gliomas via the use transcranial magnetic stimulation.The mechanisms involved such have yet be established, but they may involve preexisting routes that either are suppressed or undetected normal brain. Ipsilateral pathways act reserve, activated impairment contralateral control. This hypothesis suggested fact considerable size tumors our not matched a...
In the context of a study effects gamma-vinyl-GABA (GVG) on seizure occurrence and EEG abnormalities we present three cases with focal epilepsy in which new clinical paroxysmal manifestations were observed during GVG therapy. At that time, whereas an amelioration or no change patients' habitual seizures observed, myoclonic jerks appeared related changes abnormalities, represented by generalized polyspike wave complexes. An electroclinical correlation was recorded one case. These data...