A5012746454- Eicosanoids and Hypertension Pharmacology
- Cholesterol and Lipid Metabolism
- Gut microbiota and health
- Gastrointestinal motility and disorders
- MicroRNA in disease regulation
- Flavonoids in Medical Research
- Drug Transport and Resistance Mechanisms
- Alkaloids: synthesis and pharmacology
- Peroxisome Proliferator-Activated Receptors
- Phytochemistry and Biological Activities
- Cancer, Hypoxia, and Metabolism
- Phytochemicals and Antioxidant Activities
- Metabolomics and Mass Spectrometry Studies
- Natural product bioactivities and synthesis
- Clostridium difficile and Clostridium perfringens research
- Ferroptosis and cancer prognosis
Shandong University of Traditional Chinese Medicine
2022-2025
Shanxi Agricultural University
2024
Zhengzhou University
2024
Institute of Food Science and Technology
2024
Chinese Academy of Agricultural Sciences
2024
The gut microbiota plays an indispensable role in maintaining health. However, the imbalance of under inflammatory conditions is closely related to acceleration bowel disease...
Acanthopanax senticosus (Rupr. et Maxim.) Harms, a traditional medicinal and edible crop cultivated in China, exhibits extensive biological activities. In the present research, screening targeted isolation method using affinity ultrafiltration-UPLC-MS with GNPS (AUF-LC-MS-GNPS) methods was established used to further verify protective effect potential mechanism of monomers on vascular endothelial injury model. By utilizing AUF-LC-MS-GNPS strategy, 9 active were target isolated 22 other...
Polygonum sibiricum, with its medicinal and edibility dual properties, has been widely recognized utilized throughout Chinese history. As a kind of effective component, sibiricum polysaccharides (PSP) have reported to be promising novel antidepressant agent. Meanwhile, the precise mechanisms underlying action remain elusive. The polarization state transition microglia is intricately linked neuroinflammation, indicating crucial involvement in pathophysiology depression. Researchers are...
The betel nut is one of the most widely consumed addictive substances in world after nicotine, ethanol, and caffeine. Arecoline an active ingredient from areca nut. It has many pharmacological effects can affect central nervous system. In this study, we found that arecoline relieve fatigue behavior. Objective: This research aims to estimate anti-fatigue explore its underlying mechanisms using a murine model precipitated by sleep deprivation (SD). Methods: Seventy-two male C57BL/6 mice were...
Cydonia Oblonga Mill. is widely distributed in Turkey, Uzbekistan and China commonly used by the food industry to produce jam, jelly candies. The aim of this study was investigate vitro antidiabetic activity anti-diabetic mechanism fruit (COMF). chemical compositions were further characterized COMF UPLC-Q-Orbitrap/MS 65 components including 22 flavonoids, 16 organic acids, 11 polyphenols, 5 amino 3 pentacyclic triterpenoids 8 other compounds identified. antioxidant DPPH scavenging method...
IRN intervened in AS by modulating glycerophospholipid metabolism, linoleic acid metabolism and alpha-linolenic metabolism.
Cardiovascular diseases (CVDs) remain a key contributor to global morbidity and mortality. Being vital regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) is crucial player in CVD treatment. Recently, increasing attention has been paid the effect natural drugs on CVDs. According some studies, HIF-1α potential target for treatment traditional Chinese medicine. In this study, we describe mechanism underlying regulatory role CVDs summarize 30 3 formulations through its signaling pathway....