A5035328066- Neuroinflammation and Neurodegeneration Mechanisms
- Ginger and Zingiberaceae research
- Gut microbiota and health
- Gastrointestinal motility and disorders
- MicroRNA in disease regulation
- Tryptophan and brain disorders
- Inflammasome and immune disorders
- Moringa oleifera research and applications
- Extracellular vesicles in disease
- African Botany and Ecology Studies
- Infant Health and Development
- Epigenetics and DNA Methylation
- Medicinal Plants and Neuroprotection
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Food composition and properties
- Bioactive Compounds and Antitumor Agents
- Tea Polyphenols and Effects
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neuropharmacology Research
- Proteins in Food Systems
- Youth Substance Use and School Attendance
- Diet and metabolism studies
Yunnan Agricultural University
2023-2025
Shandong University of Traditional Chinese Medicine
2025
University of Science and Technology Beijing
2024
University of South China
2022
M. oleifera leaves represent a novel and nutritious food. Prior research has demonstrated that can elicit allergic responses in BALB/c mice. Based on these findings, further studies were conducted to investigate the effects of heat treatment allergenicity, particle size, zeta potential, total sulfhydryl (TSH) content, hydrophilicity hydrophobicity, ultraviolet spectrum, intrinsic fluorescence spectrum leaf protein. Additionally, vitro digestion experiments carried out gain insights into...
Parkinson's disease (PD) is the second most common neurodegenerative disease, but existing therapeutic drugs for PD have limitations; thus, there an urgent need to discover new methods of prevention and treatment. Amomum tsaoko Crevost et Lemarie (AT) a classic traditional Chinese medicine food. Its main pharmacological effect regulation gastrointestinal tract. To date, no studies on use AT or its extracts treat been reported. In this study, rotenone-induced mouse model was utilized evaluate...
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Constipation a prodromal symptom PD. It important to investigate pathogenesis constipation symptoms in Rotenone has been successfully used establish PD animal models. However, specific mechanism rotenone-induced not well understood. In this work, we found that appeared earlier than motor impairment mice gavaged with low dose rotenone (30 mg/kg·BW). only caused loss dopaminergic neurons and accumulation...
Acanthopanax senticosus (Rupr. et Maxim.) Harms, a traditional medicinal and edible crop cultivated in China, exhibits extensive biological activities. In the present research, screening targeted isolation method using affinity ultrafiltration-UPLC-MS with GNPS (AUF-LC-MS-GNPS) methods was established used to further verify protective effect potential mechanism of monomers on vascular endothelial injury model. By utilizing AUF-LC-MS-GNPS strategy, 9 active were target isolated 22 other...
<em>Moringa oleifera</em>(<em>M. oleifera)</em> have laxative effects, but their active compositions and mechanisms are not very clear thus far. To this end, we systematically explored the components mechanism of <em>M. oleifera</em> leaves in relieving constipation by using slow transit (STC) mouse model network pharmacology. The results animal experiments showed that aqueous extract (MOA) had good activity, its 70% alcohol soluble part (ASP) also significant activity(<em>P </em>< 0.01)....
Vidarabine (VID) is an antiviral medication that commonly utilized to treat conditions such as hand, foot, and mouth disease herpes. Constipation a prevalent complication of these diseases. Could VID diseases by influencing defecation behavior? To date, no studies have been conducted on the potential relieve constipation. Therefore, systematic investigation was into laxative effects mechanisms using loperamide-induced functional constipated mice. The findings indicate oral administration...