Yan Zhao

ORCID: 0000-0003-4632-5647
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About
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Research Areas
  • Physiological and biochemical adaptations
  • Aquaculture Nutrition and Growth
  • Aquaculture disease management and microbiota
  • Genetic diversity and population structure
  • Reproductive biology and impacts on aquatic species
  • RNA modifications and cancer
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Plant tissue culture and regeneration
  • Agriculture, Soil, Plant Science
  • Plant Ecology and Soil Science
  • Fish Ecology and Management Studies
  • Genetic and Kidney Cyst Diseases
  • Transgenic Plants and Applications
  • Renal and related cancers
  • RNA Research and Splicing
  • Identification and Quantification in Food
  • MicroRNA in disease regulation
  • Plant Water Relations and Carbon Dynamics
  • interferon and immune responses
  • Animal Genetics and Reproduction
  • Fermentation and Sensory Analysis
  • Cancer-related molecular mechanisms research
  • Seedling growth and survival studies
  • Soil Carbon and Nitrogen Dynamics
  • Plant and animal studies

Shanghai Ocean University
2014-2025

Yunnan Agricultural University
2010-2025

Hebei Medical University
2016-2024

Ministry of Agriculture and Rural Affairs
2021-2024

Zhejiang Gongshang University
2007-2024

China Medical University
2024

First Hospital of China Medical University
2024

KU Leuven
2023-2024

Guizhou University
2024

Chongqing Vocational and Technical University of Mechatronics
2024

The functions of the two proteins defective in autosomal dominant polycystic kidney disease, polycystin-1 and polycystin-2, have not been fully clarified, but it has hypothesized that they may heterodimerize to form a “polycystin complex” involved cell adhesion. In this paper, we demonstrate for first time existence native polycystin complex mouse tubular cells transgenic PKD1, non-transgenic cells, normal adult human kidney. Polycystin-1 is heavily N-glycosylated, several glycosylated forms...

10.1074/jbc.m107788200 article EN cc-by Journal of Biological Chemistry 2002-06-01

Abstract Background Chemoresistance and immunosuppression are two major obstacles in the current anti-cancer treatments. This study investigates involvements of a CCAAT enhancer binding protein delta (CEBPD)/vesicle associated membrane 3 (VAMP3) axis paclitaxel (PTX) resistance immune evasion triple-negative breast cancer (TNBC). Methods PTX resistance-related genes were screened by bioinformatics. CEBPD VAMP3 expression clinical TNBC samples was examined immunohistochemistry. Three...

10.1186/s13046-024-03041-8 article EN cc-by Journal of Experimental & Clinical Cancer Research 2024-04-16

Bermudagrass [Cynodon dactylon (L.) Pers.], an important turfgrass used in public parks, home lawns, golf courses and sports fields, is widely distributed China. In the present study, sequence-related amplified polymorphism (SRAP) markers were to assess genetic diversity population structure among 157 indigenous bermudagrass genotypes from 20 provinces The application of 26 SRAP primer pairs produced 340 bands, which 328 (96.58%) polymorphic. polymorphic information content (PIC) ranged 0.36...

10.1371/journal.pone.0177508 article EN cc-by PLoS ONE 2017-05-11

Abstract The accurate assembly of the ribonucleoprotein (RNP) complex is fundamental for replication and transcription rhabdoviruses, which are known their broad pathogenic impact. A novel 119‐amino‐acid protein, NLRP12‐119aa identified, encoded by circular RNA circNLRP12, that effectively disrupts formation rhabdovirus RNP complexes through two distinct mechanisms significantly reduces replication. exhibits a strong affinity conserved 18‐nucleotide sequence at start leader rhabdoviruses...

10.1002/advs.202409953 article EN cc-by Advanced Science 2025-01-04

Parkinson's disease (PD) is the second most common neurodegenerative disease, but existing therapeutic drugs for PD have limitations; thus, there an urgent need to discover new methods of prevention and treatment. Amomum tsaoko Crevost et Lemarie (AT) a classic traditional Chinese medicine food. Its main pharmacological effect regulation gastrointestinal tract. To date, no studies on use AT or its extracts treat been reported. In this study, rotenone-induced mouse model was utilized evaluate...

10.3390/ijms26041676 article EN International Journal of Molecular Sciences 2025-02-16

Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Constipation a prodromal symptom PD. It important to investigate pathogenesis constipation symptoms in Rotenone has been successfully used establish PD animal models. However, specific mechanism rotenone-induced not well understood. In this work, we found that appeared earlier than motor impairment mice gavaged with low dose rotenone (30 mg/kg·BW). only caused loss dopaminergic neurons and accumulation...

10.3390/ijms26052079 article EN International Journal of Molecular Sciences 2025-02-27

Ulcerative colitis (UC) is a global disease for which there little of effective treatment options, thus creating an urgent need the development new drug candidates from natural and functional foods. Amomum tsaoko Crevost et Lemarie kind medicinal food herb that rich in flavonoids. However, pharmacological effects flavonoids (ATF) on UC have not yet been reported. The present study established mouse model using 3% dextran sulfate sodium (DSS), modern molecular biology techniques such as IHC,...

10.3389/fmicb.2025.1557778 article EN cc-by Frontiers in Microbiology 2025-03-10

Objectives To explore the phenotype and role of gamma delta (γδ) T cells in pathogenesis IgG4-related disease (IgG4-RD). Methods Flow cytometry quantitative RT-PCR were employed to analyze γδ cell subsets, chemokine receptor expression, cytokine production, pro-fibrotic gene transcription factor profiles. Immunofluorescence assessed Vδ2 infiltration affected tissues. Chemotaxis assays co-culture experiments investigated migration their influence on B differentiation. The impact IL-21...

10.3389/fimmu.2025.1550405 article EN cc-by Frontiers in Immunology 2025-03-27

Abstract Apparel has the potential to influence external expression of wearer’s emotional state and can even empower them, making patients’ hospital wearing a crucial factor in their experience medical treatment. This study aims investigate factors that drive behavioral responses gowns using pleasure–arousal–dominance (PAD) model. With survey conduction data analysis, results identified color silhouette lead arousal, while structure leads dominance, which turn brings patients high sense...

10.1515/aut-2023-0010 article EN cc-by Autex Research Journal 2024-01-01

The igfbp family proteins are key regulators of the biological activities igfs, which play a pivotal role in controlling growth. Growth is highly variable between different fish species and even growth stages sexes within same species. For determining igfbps significantly associated to growth, we identified genes from whole-wide genomes mandarin Siniperca chuatsi big-eye kneri, detected their expression profiles under conditions. results revealed that: 1) both have 10 members (igfbp-1a/b,...

10.1016/j.aqrep.2024.101971 article EN cc-by-nc-nd Aquaculture Reports 2024-02-09

10.1016/j.bbrc.2014.10.068 article EN Biochemical and Biophysical Research Communications 2014-10-18
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