A5103059568- Plant tissue culture and regeneration
- Cancer, Hypoxia, and Metabolism
- Thyroid Cancer Diagnosis and Treatment
- Plant Physiology and Cultivation Studies
- Cancer Immunotherapy and Biomarkers
- Adrenal and Paraganglionic Tumors
- Pancreatic and Hepatic Oncology Research
- Cancer-related Molecular Pathways
- EFL/ESL Teaching and Learning
- Genetic and Kidney Cyst Diseases
- Neuroendocrine Tumor Research Advances
- Pituitary Gland Disorders and Treatments
- Renal and related cancers
- Lung Cancer Treatments and Mutations
- Plant Reproductive Biology
- Cancer Genomics and Diagnostics
- Esophageal Cancer Research and Treatment
- Cancer Cells and Metastasis
- Cell death mechanisms and regulation
- Genetic factors in colorectal cancer
- Horticultural and Viticultural Research
- Mesenchymal stem cell research
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Subtitles and Audiovisual Media
Sun Yat-sen University
2012-2023
The First Affiliated Hospital, Sun Yat-sen University
2018-2023
First Affiliated Hospital Zhejiang University
2021
Wenzhou Medical University
2006-2015
117th Hospital of People's Liberation Army
2012-2014
Anhui Medical University
2014
Shaoguan University
2005-2007
Fujian Agriculture and Forestry University
2000
Genetic screening for germline mutations in the RET proto-oncogene has been extensively exploited worldwide to optimize diagnostic and clinical management of multiple endocrine neoplasia type 2 (MEN2) patients their relatives. However, a distinct lag period exists not only recognition but also medical treatment with MEN2. Here we present comprehensive genetic analysis MEN2 among Chinese families followed from 1975 2011. Our series comprises 36 index cases 134 relatives 11 independent...
Abstract Mesenchymal stromal cells (MSCs) have been considered as one of the pivotal type composing tumor microenvironment. Although contact-dependent mechanisms and paracrine factors are thought to collaborate in governing MSCs-based effects on tumors progression, underlying remain largely unknown. In particular, involvement MSCs-derived cytokines epithelial–mesenchymal transition (EMT) esophageal squamous cell carcinoma (ESCC) has not clarified. this study, we observed that...
// Xiao-Ping Qi 1 , Jian-Qiang Zhao 2 Zhen-Guang Chen Jin-Lin Cao Juan Du 3 Nai-Fang Liu Feng Li Mao Sheng Er Fu Jian Guo 1, 5 Hong Jia 4 Yi-Ming Zhang Ju-Ming Ma Department of Oncologic and Urology Surgery, the 117th PLA Hospital, Wenzhou Medical University, Hangzhou 310004, Zhejiang Province, China Head Neck Cancer 310022, Academy Sciences, 310007, Institute Dermatology, Chinese Sciences Peking Union College, Nanjing 210042, Jiangsu Correspondence to: Qi, e-mail: qxplmd@vip.sina.com...
Von Hippel-Lindau (VHL) disease is an autosomal dominant familial cancer syndrome. VHL characterized by the development of renal cell carcinoma (RCC), hemangioblastomas central nervous system or retina and pheochromocytoma (PCC). RCC PCC are known to be caused germline mutations six ten genes, respectively. In present study, 30 individuals from two unrelated pedigrees with type 2A 2C syndrome were investigated. The patients clinically examined treated radical nephrectomy [or nephron‑sparing...
To explore the clinical characteristics and significance of RET proto-oncogene screening in multiple endocrine neoplasia type 2A (MEN2A).Comprehensive medical history was obtained for 5 members from a 3-generation family southern China. Clinical investigations have included biochemical testing, imaging, germline mutations.Genetic has revealed missense mutation at codon 618(TGC>CGC) exon 10 3 patients(p.C618R), which consistent with their manifestations. For individuals, age diagnosis 21, 26...
The differential diagnosis of progression and pseudoprogression is one difficulty in current immunotherapy. Since the time point criteria for are not yet unified, treatment rely on imaging pathology. Here we report a 57-year-old Chinese male presented solitary left lower lung nodule with enlarged hilar mediastinal lymph nodes. Bilateral adrenal nodules bilateral parietal lobe were identified. considered malignant by CT or MRI examinations. patient was diagnosed peripheral cancer node...
Objective: To investigate p16, C-fos protein expression and their relationships in osteosarcoma. Methods: Immunohistochemical technique (SABC) was used to detect p16 41 cases of Results: The positive rates were 51.2% 82.9% respectively. Their not correlated pathological subtype, but clinic grade, the latter associated with tumor metastasis. There a negative correlation between expression. Conclusion: alteration may be related tumorigenesis development osteosarcoma, proteins take part...
Objective To study the clinical features of bilateral adrenal pheochromocytomas (PHEO) in patients associated with multiple endocrine neoplasia type 2A (MEN2A) and to evaluate safety feasibility applying simultaneous adrenalectomy (SBA).Methods From November 2003 April 2011,clinical data 8 from 4 unrelated MEN2A families treated SBA were analyzed.There 6 males 2 females.The mean age was 44 years (range,35 56 years).4 asymptomatic had related PHEO.The diagnosis PHEO made after MTC...