A5014282287- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Head and Neck Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Cerebrospinal fluid and hydrocephalus
- Oral and Maxillofacial Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Olfactory and Sensory Function Studies
- Tracheal and airway disorders
- Allergic Rhinitis and Sensitization
- Neurosurgical Procedures and Complications
- Adrenal and Paraganglionic Tumors
- Infectious Diseases and Mycology
- Lymphoma Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Cleft Lip and Palate Research
- Asthma and respiratory diseases
- Teratomas and Epidermoid Cysts
- Obstructive Sleep Apnea Research
- Drug-Induced Adverse Reactions
University of California, Irvine
2016-2025
Neurological Surgery
2020-2025
UC Irvine Health
2019-2025
University of California, Irvine Medical Center
2018-2024
University of California, Los Angeles
2014-2023
University of Pennsylvania Health System
2018-2023
Pioneer (United States)
2023
American Academy of Otolaryngology — Head and Neck Surgery
2023
Temple University
2023
AID Atlanta
2023
Squamous cell carcinoma of the lip (lip SCC) composes more than 25% all oral cancers. Most demographic and prognostic indicators for SCC are only available through retrospective case series.To examine incidence, treatment, overall survival, disease-specific survival (DSS) patients with SCC.Population-based cohort analysis using Surveillance, Epidemiology, End Results database identified between January 1, 1973, December 31, 2012.Overall DSS.A total 15 832 cases were identified. The was...
Key points In this multi‐center sinonasal malignancies (SNM) cohort, the Sino‐nasal Outcome Test has a correlation with University of Washington Quality Life (UWQOL) for assessing QOL. The use both instruments remains recommended to provide complete and complementary information. Future design an easy‐to‐use tool specific SNM is needed encompass all aspects
Background Posterior nasal nerve (PNN) cryoablation improves chronic rhinitis (CR) symptoms in 70–80% of cases, including clear thin rhinorrhea (CTR). This study's purpose was to determine time and degree CTR recurrence following cryoablation. Methods A multicenter retrospective cohort study conducted on patients who underwent PNN treat CR‐related refractory ipratropium bromide spray (IBNS). Cryoablation applied along middle meatal posterolateral walls. Demographic clinical data were...
Sinonasal mucosal melanoma has poor survival despite multimodality treatment. While the impact of immunotherapy (IT) on metastatic cutaneous is well-defined, there are relatively little data sinonasal melanoma. We sought to define outcomes in patients with A retrospective cohort study evaluated treated IT during their overall treatment strategy for SNMM. Patient demographics, treatment, and were recorded. 52 had SNMM from 2000 2022, an average age 69.1 ± 11.9 years. The most common was...
Background Dupilumab was first approved by the United States Food and Drug Administration in 2017 for atopic dermatitis has since been many other indications. The use of dupilumab grown, but industry payments to physicians have yet be explored. Objective study objective is characterize change pharmaceutical companies dupilumab-related promotional activities. Methods Data from 2023 extracted Open Payments website filtered determine number physicians, amounts these payments, unique that were...
Objectives/Hypothesis To utilize the Surveillance, Epidemiology, and End Results (SEER) database to elucidate differences in predictors of survival oral tongue squamous cell carcinoma (OTSCC) as stratified by age sex. Study Design Retrospective, population‐based analysis. Methods The SEER registry was utilized calculate trends for patients with OTSCC between 1973 2012. Patient data were then (≤40 years vs. >40 years) sex, analyzed respect race, stage, grade, treatment modalities. Overall...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is commonly characterized by type‐2 inflammation. It established that group‐2 innate lymphoid cells (ILC2s) are a subset of immune important in orchestrating mucosal response. IL‐25 an epithelial‐derived cytokine critical activator ILC2s. Recent evidence demonstrates specialized taster epithelial cells, such as solitary chemosensory (SCCs), may be producers IL‐25. To elucidate the relationship between SCCs and ILC2s CRSwNP, we...
Objectives/Hypothesis The purpose of this study was to investigate the association demographic factors, tumor stage, and treatment modalities for overall survival in patients with sinonasal mucosal melanoma (SNMM). Study Design Retrospective database review. Methods National Cancer Database queried all ages SNMM between 2004 2015. Univariate Kaplan‐Meier multivariate Cox regression analyses were performed evaluate suspected prognostic factors survival. Results A total 1,874 included...
To evaluate the impact of preoperative frailty on short-term outcomes following complex head and neck surgeries (HNSs).Cross-sectional database analysis.American College Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database.The 2005 to 2017 ACS-NSQIP was queried for patients undergoing HNS. Five-item modified index (mFI) calculated based functional status history diabetes, chronic obstructive pulmonary disease, congestive heart failure, hypertension.A total 2786 (73.1%...
BACKGROUND:In this study, we identified key discrete clinical and technical factors that may correlate with primary reconstructive success in endoscopic skull base surgery (ESBS). METHODS: ESBS cases intraoperative cerebrospinal fluid (CSF) leaks at four tertiary academic rhinology programs were retrospectively reviewed. Logistic regression associated surgical outcomes by defect subsite (anterior cranial fossa [ACF], suprasellar [SS], purely sellar, posterior [PCF]). RESULTS: Of 706 patients...
Abstract Background Patients with sinonasal malignancy (SNM) present significant quality of life (QOL) impairment. Global QOL as measured by the 22‐item Sinonasal Outcomes Test (SNOT‐22) has been shown to improve treatment. This study aims characterize SNOT‐22 subdomain outcomes in SNM. Methods diagnosed SNM were prospectively enrolled a multi‐center patient registry. scores collected at time diagnosis and through post‐treatment period for up 5 years. Multivariable regression analysis was...
Abstract The goal of this American Rhinologic Society expert practice statement (EPS) is to summarize the best available evidence for technical factors that optimize outcomes in skull base reconstruction following endoscopic surgery intradural pathologies. These topics include use free mucosal grafts versus vascularized pedicled nasoseptal flaps; autologous synthetic grafts; and roles lumbar drains, dural sealants, nasal packing. This EPS was developed recommended methodology approval...
Objectives/Hypothesis Currently, due to the rarity of pathology, there are limited data surrounding outcomes pediatric skull base surgery. Traditionally, surgeons have proceeded with caution when electing endonasal endoscopic transsellar/transplanum approaches in patients poor sphenoid pneumatization. In this study, we review surgery based on pneumatization patterns. Study Design Retrospective chart review. Methods A all cases (age < 18 years) craniopharyngioma managed via an approach at...
Background Outcome studies on sinonasal malignancy are limited to retrospective case series, often with inclusion of diverse histology and short follow-up. The objective this study was identify key predictive variables that independently impact survival for paranasal sinus squamous cell carcinoma (SCC) adenocarcinoma (AC) compare these in the context two distinct clinicopathologic entities. Methods: Analysis conducted using Surveillance, Epidemiology, End Results database from 1973 2012 SCC...
To describe the incidence and determinants of survival patients with sinonasal undifferentiated carcinoma (SNUC) from 1973 to 2011 using SEER database (Surveillance, Epidemiology, End Results), consideration tumor stage based on Kadish system.Retrospective analysis.Academic medical center.The registry was utilized calculate trends for 328 SNUC between 2011. Patient data were then analyzed respect histopathology, age, sex, race, subsite, modified stage, size, treatments rendered.The cohort...
Background The gold standard of treatment for esthesioneuroblastoma consists en bloc craniofacial resection with postoperative therapy dictated by histology and tumor extent. Numerous studies have shown fully endoscopic approaches to provide comparable survival recurrence rates decreased patient morbidity. Here we report the first multi-institutional series assessing smell outcomes patients who underwent unilateral preservation contralateral olfactory bulb. Methods A retrospective review was...