Objective: The study was designed to evaluate the effects of strength training (ST) on bone mineral density (BMD) postmenopausal women without hormone replacement therapy. Method: Subjects were randomized into untrained (UN) or trained (TR) groups. TR group exercised three ST sessions per week for 24 weeks, and body composition, muscular strength, BMD lumbar spine femur neck evaluated. Results: Body weight, mass index, fat percentage lower after weeks only in ( p < .05). SR also improved...

Although echocardiography has been used in rats, few studies have determined its efficacy for estimating myocardial infarct size. Our objective was to estimate the size, and evaluate anatomic functional variables of left ventricle. Myocardial infarction produced 43 female Wistar rats by ligature coronary artery. Echocardiography performed 5 weeks later measure ventricular diameter transverse area (mean 3 planes), size (percentage arc with on systolic function change fractional area,...

FUNDAMENTO: A literatura tem descrito dados contraditórios em relação ao início da diminuição função barorreflexa ratos espontaneamente hipertensos. OBJETIVO:Este estudo foi realizado para avaliar a jovens de 13 semanas MÉTODOS:Foram estudados machos Wistar Kyoto (WKY) (n=15) e hipertensos (REH) (n=15). Cânulas foram inseridas na artéria aorta abdominal através femoral direita medir pressão arterial média (PAM) freqüência cardíaca (FC). calculada como derivada variação FC PAM (ΔFC/ΔPAM),...

Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer’s disease. Previous studies have suggested that blockers act as neuroprotective agents; however, no study has specifically investigated the impact these drugs on heart. We sought evaluate effects of memantine nuclear size reduction in cardiac cells exposed cold stress. male EPM-Wistar rats (n=40) divided into 4 groups: 1) Matched control (CON); 2) Memantine-treated (MEM); 3) Rats undergoing...

Summary Introduction: Obstructive sleep apnea and hypopnea syndrome (OSAHS) is one of the developmental factors high blood pressure (HBP), a relevant global public health problem. OSAHS characterized by reduction or complete cessation respiratory airflow due to intermittent airway collapse. Additionally, significant changes in rhythm pattern are observed these patients. Objective: To evaluate association between quality essential resistant hypertensives. Method: A cross-sectional,...

Total body induced hypothermia and myocardial cooling are effective methods regarding protection during heart surgery ischemia. It is described in previous studies that extreme low temperature exposure causes mitochondrial cristae myofilament disarrangement cardiomyocytes, however, no investigation has analyzed the effects of cold stress on nuclear size cardiomyocytes.To evaluate acute cardiomyocytes rats.The experimental study procedures were performed 300-310 g adult male Wistar rats. Rats...

To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress.The experimental study procedures were performed 250-300g male EPM-Wistar rats. Rats (n=40) divided into four groups: 1) Control group (CON); 2) Fluoxetine (FLU); 3) Induced hypothermia (IH) and; 4) treated with (IHF). Animals FLU by administration gavages containing 0.75 mg/kg/day during 40 days. The induced was obtained maintaining groups 3 and 4 a freezer at -8 degrees C for...

Summary Introduction: acute coronary syndromes (ACS) represent a widely prevalent health issue with high mortality in Brazil and worldwide. The severity of ACS is not known patients the city São Bernardo do Campo municipality contiguous adjacent to Paulo. Objectives: study profile disease hospitalized who underwent angiography emergency room between 2012 2013. Methods: this an observational that included consecutive admitted hospital. Data collection was performed using medical records...

Introduction Diabetic nephropathy (DN) is a disease that progresses with the slow and progressive decline of glomerular filtration rate (GFR); installation this pathology silent one major causes death in patients diabetes. Aims To identify new molecular biomarkers for early identification onset DN type II diabetes mellitus (DM2). We studied expression profile genes; suppressor mothers against decapentaplegic 1 ( SMAD1 ), neutrophil gelatinase-associated lipocalin NGAL ) IV collagen COLIV1A...

Introduction: Total body induced hypothermia and myocardial cooling are effective methods regarding protection during heart surgery ischemia. It is described in previous studies that extreme low temperature exposure causes mitochondrial cristae myofilament disarrangement cardiomyocytes, however, no investigation has analyzed the effects of cold stress on nuclear size cardiomyocytes. Objectives: To evaluate acute cardiomyocytes rats. Methods: The experimental study procedures were

We assessed the effect of topical application epsilon-aminocaproic antifibrinolytic acid (EACA) on pericardium patients submitted to coronary artery bypass graft (CABG) without use cardiopulmonary (CPB). This is a prospective, randomized, and double-blind study. evaluated 26 with chronic heart disease indicated for CABG CPB (EACA placebo groups). The analysis postoperative hematological results showed no difference between groups in hemoglobin hematocrit. There was regarding bleeding through...

SUMMARY 1. The aim of the present study was to analyse possible lack uniformity in isoproterenol (ISO)‐induced myocardial hypertrophy. 2. Data obtained for isovolumic hearts isolated from 20 rats treated with ISO (0.3 mg/kg over 8 days) were divided into two groups (H 1 , n = 10; H 2 10) according volume (mean±SD) needed change left ventricle diastolic pressure 0 40 mmHg 184±30 μL; 108±14 μL). Eight control (C; 165±37 μL) used comparison. 3. In addition ventricular distensibility...

A caracterização das hemorragias periventriculares-intraventriculares (HPIV) no período neonatal em recém-nascidos pré-termo constitui um evento importante para a prevenção de seqüelas curto e longo prazo. Foi objetivo deste estudo avaliar freqüência da hemorragia peri-intraventricular correlacioná-la com o peso ao nascer, num observacional transversal realizado uma unidade terapia intensiva neonatal, do Hospital Servidor Público Estadual (HSPE), na cidade São Paulo janeiro 1996 dezembro...

Background: Memantine attenuates heart stress due cold stress, however, no study focused its effects on liver and adrenal gland.We evaluated lipid depletion in gland glycogen of rats exposed to stress.Methods: Male divided into 4 groups: 1)Control (CON); 2)Memantine (MEM); 3)Induced (IH) and; 4)Induced memantine (IHF).Memantine were administrated by gavage (20 mg/kg/day) during eight days.Cold performed hours once at -8°C.Lipid presented as intensity levels.Results: Rats the highest (p <...

Cardiomyocytes cytoarchitecture changes caused by transthoracic countershocks have been focused recently. We aimed to evaluate the effects of electrical discharge application in mitochondria structure atrial myocardium rats.An cardioverter was adapted small rodent animals for our research. Electrical discharges were applied precordial region 30 albino rats: (1) control group - that remained on resting period and afterwards sacrificed; (2) period, followed ten 300 mV sacrificed, and; (3)...

Cold exposure induces glycogen and lipid depletion in the liver adrenal gland, respectively. However, no previous study has determined effects of electrical countershock on those tissues. We aimed to evaluate gland liver. used 40 male Wistar rats divided into four groups: control group, which animals were subjected a resting period seven days; discharge followed by administration ten 300-mV discharges; post-discharge received shocks (300 mV) rest for consecutive cold stress then exposed −8ºC...

This study compared maximum oxygen consumption (VO2max) on a 20-meter multistage shuttle run test (20-Srt) with cardiopulmonary exercise (CPET) to determine VO2max prediction equation for 20-Srt in children aged 6-10 years. Eighty healthy performed the CPET treadmill, while took place sports court. Heart rate (HR) was measured and expired gases were continuously breath-by-breath using portable gas analyzer. The lower (p<0.05) than all, female, male participants, respectively (46.3±7.9 vs....

OBJETIVO: Verificar o efeito da denervação cardíaca ventral na incidência de fibrilação atrial no pós-operatório revascularização cirúrgica do miocárdio. MÉTODOS: Entre setembro e novembro 2005, 50 pacientes consecutivos mesma instituição foram alocados neste estudo prospectivo randomizado. Foram selecionados portadores insuficiência coronariana com indicação miocárdio, sem história ou diagnóstico prévio arritmia atrial. Os critérios exclusão foram: idade acima 75 anos, prévia operações...

Background: Diabetic nephropathy (DN) is a disorder affecting glomerular function that, histologically, due to the presence of glomerulosclerosis accompanied with endothelial dysfunction afferent and efferent renal arterioles. Insulin resistance in diabetic patients known be one causes because it increases oxidative stress, main genes regulating production pathways reactive oxygen species p66Shc. The aim this study was evaluate p66Shc gene expression as precocious biomarker patients, using...

The aim of this study was to investigate the role irisin in type 2 diabetes mellitus and its association with metabolic alterations obesity.A cross-sectional case-control conducted on participants treated at Centro Universitário FMABC between August 2018 July 2019, by comparing a control group (n=14) patients (n=16). consisted aged above 21 years no chronic diseases, diabetes, smoking, or illicit drug use. included years, who were diagnosed for least 5 (glycated hemoglobin>7%). Exclusion...