A5002599414- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Cardiomyopathy and Myosin Studies
- Ion channel regulation and function
- Sarcoidosis and Beryllium Toxicity Research
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Pericarditis and Cardiac Tamponade
- Cardiac Valve Diseases and Treatments
- Restraint-Related Deaths
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Infectious Encephalopathies and Encephalitis
- Career Development and Diversity
New York University
2017-2025
NYU Langone Health
2015-2024
Brigham and Women's Hospital
2011-2023
Hinge Health
2020-2022
Lincoln Medical Center
2022
Tanta University Hospital
2022
University of Milan
2020
Kyowa Hakko Kirin (Singapore)
2020
San Diego Cardiac Center
2020
Ospedale San Paolo
2020
There is no known effective therapy for patients with coronavirus disease 2019 (COVID-19). Initial reports suggesting the potential benefit of hydroxychloroquine/azithromycin (HY/AZ) have resulted in massive adoption this combination worldwide. However, while true efficacy regimen unknown, initial raised concerns about risk QT interval prolongation and induction torsade de pointes (TdP).
Background— Cardiac sarcoid–related ventricular tachycardia (VT) is a rare disorder; the underlying substrate and response to ablation are poorly understood. We sought examine outcomes of catheter in this population. Methods Results— Of 435 patients with nonischemic cardiomyopathy referred for VT ablation, 21 (5%) had cardiac sarcoidosis. Multiple inducible VTs were observed mechanism consistent scar-mediated re-entry all VTs. Voltage maps showed widespread confluent right scarring. Left...
Abstract In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing most common cardiac arrhythmia. 2007, first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence technological advances have resulted a rapidly changing landscape field ablation, thus stressing need regularly updated versions this partnership which were...
In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing most common cardiac arrhythmia. 2007, first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence technological advances have resulted a rapidly changing landscape field ablation, thus stressing need regularly updated versions this partnership which were issued...
In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing most common cardiac arrhythmia. 2007, first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence technological advances have resulted a rapidly changing landscape field ablation, thus stressing need regularly updated versions this partnership which were issued...
Abstract We report the change in QT interval 84 adult patients with SARS-CoV-2 infection treated Hydroxychloroquine/Azithromycin combination. QTc prolonged maximally from baseline between days 3 and 4. 30% of increased by greater than 40ms. In 11% to >500 ms, representing high risk group for arrhythmia. The development acute renal failure but not was a strong predictor extreme prolongation.
Ventricular tachycardia (VT) refractory to antiarrhythmic drugs and standard percutaneous catheter ablation techniques portends a poor prognosis. We characterized the reasons for failure describe alternative interventional procedures in this high-risk group.Sixty-seven patients with VT 4±2 2±1 previous endocardial/epicardial attempts underwent transcoronary ethanol ablation, surgical epicardial window (Epi-window), or cryoablation (OR-Cryo; age, 62±11 years; storm 52%). Failure of...
Abstract Background The emergence of the COVID-19 pandemic has resulted in over two million affected and 150 thousand deaths to date. There is no known effective therapy for disease. Initial reports suggesting potential benefit Hydroxychloroquine/Azithromycin (HY/AZ) have massive adoption this combination worldwide. However, while true efficacy regimen unknown, initial raised concerns regarding risk QT prolongation induction torsade de pointes (TdP). Methods This a multicenter retrospective...
To correlate impedance decrease during atrial fibrillation (AF) ablation with lesion durability and PV conduction recovery demonstrated redo procedures.Markers of successful beyond acute block are needed to improve pulmonary vein (PV) isolation (PVI). Local resulting from is a real-time marker tissue heating correlated creation.Impedance changes associated point-by-point radiofrequency in the antra were recorded 167 consecutive first-time AF ablations. During clinically indicated procedures,...
Background Cardiac resynchronization therapy (CRT) increases transmural dispersion of repolarization (TDR) and can be pro‐arrhythmic. However, overall arrhythmia risk was not increased in large‐scale CRT clinical trials. Increased TDR as measured by T peak –T end (TpTe) associated with a single‐center study. This study investigates whether QT interval, TpTe, TpTe/QT ratio are ventricular arrhythmias patients CRT‐defibrillator (CRT–D). Methods Post‐CRT–D implant electrocardiograms 128 (age...
The initial impedance decrease during radiofrequency (RF) ablation is an indirect marker of catheter contact and lesion formation. We aimed to assess feasibility, efficacy, safety approach guided by decrease.A total 25 patients with paroxysmal AF had point-by-point, wide antral pulmonary vein (PV) isolation. RF applications were aborted if a at least 5 Ω did not occur in the first 10 seconds; otherwise, was continued for 20 seconds. Power 30 Watts reduced 15-25 on posterior wall.A 28%...
Radiofrequency ablation (RFA) from the epicardial space for ventricular arrhythmias is limited or impossible in some cases. Reasons failure and effect on outcome have not been systematically analyzed.We assessed reasons RFA relative to anatomic target area type of heart disease failed after procedures a large single-center cohort. Epicardial access was attempted during 309 277 patients achieved 291 (94%). Unlimited an identified region could be performed 181 cases (59%), possible 22 (7%),...
Abstract Introduction Catheter stability during atrial fibrillation ablation is associated with higher success rates. Rapid cardiac pacing and high‐frequency jet ventilation (HFJV) independently improve catheter stability. Simultaneous modulation of respiratory motion has not been previously studied. The objective this study was to determine the effect simultaneous heart rate on Methods Forty patients undergoing paroxysmal received lesions at 15 prespecified locations (12 left atria, 3 right...