Manna Valiathan

ORCID: 0000-0003-3496-9920
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About
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Research Areas
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Ovarian cancer diagnosis and treatment
  • Breast Lesions and Carcinomas
  • Salivary Gland Tumors Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Photoreceptor and optogenetics research
  • Oral and Maxillofacial Pathology
  • Tumors and Oncological Cases
  • Sarcoma Diagnosis and Treatment
  • Cancer and Skin Lesions
  • Erythrocyte Function and Pathophysiology
  • Bone Tumor Diagnosis and Treatments
  • Teratomas and Epidermoid Cysts
  • Uterine Myomas and Treatments
  • Retinal Development and Disorders
  • Neurofibromatosis and Schwannoma Cases
  • Head and Neck Surgical Oncology
  • Ear and Head Tumors
  • Hematological disorders and diagnostics
  • Infectious Diseases and Mycology
  • Reproductive Biology and Fertility
  • Assisted Reproductive Technology and Twin Pregnancy
  • Craniofacial Disorders and Treatments
  • Ear Surgery and Otitis Media
  • Actinomycetales infections and treatment

Kasturba Medical College, Manipal
2014-2023

Manipal Academy of Higher Education
2014-2023

Apollo Hospitals
2020

RELX Group (United States)
2014

Microsoft (Brazil)
2014

An optical trap has been combined with a Raman spectrometer to make high-resolution measurements of spectra optically-immobilized, single, live red (RBC) and white blood cells (WBC) under physiological conditions. Tightly-focused, near infrared wavelength light (1064 nm) is utilized for trapping single 785 nm used excitation at low levels incident power (few mW). RBC recorded using this high-sensitivity, dual-wavelength apparatus enabled identification several additional lines; the...

10.1371/journal.pone.0010427 article EN cc-by PLoS ONE 2010-04-29

10.1016/j.jphotobiol.2010.05.009 article EN Journal of Photochemistry and Photobiology B Biology 2010-06-03

We report here results of a single-cell Raman spectroscopy study stress effects induced by silver nanoparticles in human mesenchymal stem cells (hMSCs). A high-sensitivity, high-resolution Tweezers set-up has been used to monitor nanoparticle-induced biochemical changes optically-trapped single cells. Our micro-Raman spectroscopic reveals that hMSCs treated with undergo oxidative at doping levels excess 2 µg/ml, statistical analysis spectra suggesting the becomes more dominant nanoparticle...

10.1371/journal.pone.0035075 article EN cc-by PLoS ONE 2012-04-13

Blue light exposure-induced retinal damage has been extensively studied. Although many in vitro studies have shown the benefits of blue light-blocking lenses (BBL) there few comprehensive vivo to assess effects BBL. We investigated influence exposure using light-emitting diodes on histology and visual cortex neurons rodents. also considered whether cortical changes induced by could be ameliorated with lenses. A total n = 24 (n 6 each group; control, without lenses, two different BBLs)) male...

10.3390/life12020243 article EN cc-by Life 2022-02-07

Myeloid sarcoma (MS) is a rare tumor composed of proliferation myeloid precursors at extramedullary sites. They can arise de-novo or in association with hematological malignancies, most commonly acute leukemia. Clinically, it masquerade as an abscess, cutaneous ulcer, mass lesion. Morphologically, MS mimic variety small round cell tumors including lymphomas and rhabdomyosarcoma.(1) To study the clinical presentations laboratory findings patients MS; (2) to revisit histomorphological...

10.4103/0973-1482.220418 article EN PubMed 2017-12-15

Splenic tuberculosis is an unusual manifestation of extrapulmonary tuberculosis, especially in immunocompetent hosts. It often poses diagnostic difficulties as microbiological confirmation not easy. In this case report, we describe a pseudocyst the spleen due to which rare clinical presentation with only one having been reported previously.1 A 24-year-old woman presented pain abdomen, vomiting and fever. On evaluation patient was found have cyst arising from spleen. Splenectomy performed....

10.1136/bcr-2014-203596 article EN BMJ Case Reports 2014-05-13

An isolated polyp arising from the sphenoid sinus is rare. Due to presence of important structures adjacent sinus, a proper pre-operative radiological and nasal endoscopic evaluation mandatory, along with neurological ophthalmological assessment. We report case 23-year-old man sphenochoanal heterotopic glial tissue in stroma. A Medline search did not reveal any previously reported cases presenting as polyp.

10.1017/s0022215106004543 article EN The Journal of Laryngology & Otology 2006-11-30

We report a case of middle aged, hypertensive man who presented with nasal obstruction, sneezing spells, headache and discharge long duration. On evaluation, he was diagnosed to have deviated septum allergic rhinosinusitis sinonasal polyposis. CT the paranasal sinuses revealed hyperdense, oval structure suggestive sinolith in right anterior ethmoid sinus. The patient underwent septoplasty Draf 2B procedure extraction from

10.1136/bcr-2014-204157 article EN BMJ Case Reports 2014-03-31

Blue light exposure induced retinal damage has been extensively studied. Retinal damages are closely associated with cellular and biochemical changes occurring in the vitreous hence, understanding metabolic tissue might serve as clinical importance to indicate ocular/vision health. In present study, we have investigated influence of blue light-emitting diodes (LED) on metabolome further, show amelioration altered metabolite levels upon blocking lenses (BBLs). A total n = 24 (n 6 each group;...

10.1016/j.jksus.2022.101986 article EN cc-by-nc-nd Journal of King Saud University - Science 2022-03-20

10.1016/j.tripleo.2005.08.011 article EN Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology 2006-02-20

Schwannomas account for around half of all intradural spinal tumours, with chronic progressive symptoms as the most common presenting features. Intratumoural haemorrhage a feature schwannoma is very rare and only 11 cases have been reported till date. Authors here report previously asymptomatic 40-year-old male who presented acute onset paraplegia 12 hours after minor trauma. MR imaging revealed C7-D3 intradural-extramedullary lesion features blood showing no enhancement. Emergency...

10.7860/jcdr/2016/16187.7015 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2016-01-01

Ovarian pregnancy is a rare form of ectopic following ICSI-ET, and the diagnosis depends on physicians suspicion experience. Preservation ovarian tissue during surgery utmost importance to preserve fertility. We present case who had successful treatment preserving ovary.

10.1155/2012/389107 article EN cc-by Case Reports in Obstetrics and Gynecology 2012-01-01

We synthesized twenty thiazolidin-4-one derivatives, which were then characterized by standard chromatographic and spectroscopic methods. From the in vitro glucose uptake assay, two compounds behaved as insulin sensitizers, where they enhanced isolated rat diaphragm. In high-carbohydrate diet-induced resistant mice, these thiazolidin-4-ones attenuated hyperglycemia, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia, intolerance. They raised plasma leptin but did not reverse...

10.1155/2014/620434 article EN cc-by BioMed Research International 2014-01-01

The exposure to blue and white Light emitting diodes (LED) light leads damage in the visual system with short-term LED exposure. Chronic exposure, adaptive responses light, self-protective mechanisms against exposures need be explored, it would essential understand repercussions of radiation on vitreous metabolites. A total 24 male Wistar rats were used this study, divided into four groups (n = 6 each group). Three experimental exposed either blue, white, or yellow for 90 days (12:12...

10.3390/metabo13010081 article EN cc-by Metabolites 2023-01-03

Mucoepidermoid carcinoma (MEC) is known to be a relatively common neoplasm of the major and minor salivary glands that can secondarily involve skin. The clinical manifestations, diagnostic cytology histopathology MEC presenting as clinically benign periauricular cystic nodule have been analyzed. challenge accurate diagnosis illustrated by fact initially, on cytology, this tumor was misdiagnosed epidermal inclusion cyst due presence mucin-filled cells which were misinterpreted macrophages....

10.4103/jomfp.jomfp_277_21 article EN Journal of Oral and Maxillofacial Pathology 2022-02-01

Abstract Background The molecular makeup of a head and neck squamous cell carcinoma (HNSCC) could vary as per the geography corresponding variability in prevalent etiopathological factors. objective this study was to analyze expression pattern E-cadherin (E-cad), transmembrane glycoprotein with tumour suppressor function, cohort HNSCC treated at tertiary care medical centre southern part India. Material methods After obtaining institutional ethics committee’s permission, E-cad assessed by...

10.1186/s43163-023-00503-2 article EN cc-by The Egyptian Journal of Otolaryngology 2023-09-05

Case RepoRtA 17-year-old girl with previously normal menstrual cycles visited gynecology out patient department of a tertiary care hospital complains amenorrhea 18 months duration, hirsutism for 12 and abdominal distension since 4 months.Six after developing amenorrhea, she started excessive hair growth on the face, arms, abdomen chest.She also noticed reduction in size breast hoarseness voice.Cushingoid features were absent.On per examination, mass measuring 22x15 cm was palpated bilateral...

10.7860/jcdr/2015/12311.6145 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2015-01-01

Synchronous tumours of different histological types involving the salivary gland are very rare. There have been cases reported in literature such occurring parotid gland. A 52-year-old man presented with a 4-year history gradually increasing painless swelling right submandibular region. The ultrasound scan neck showed features suggestive sialadenitis. was then surgically excised and sent for histopathological examination. unique dual pathology gland, that is, plasmacytoma pleomorphic...

10.1136/bcr-2013-202463 article EN BMJ Case Reports 2014-03-03
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