A5014075370- Studies on Chitinases and Chitosanases
- Enzyme Production and Characterization
- Protein Hydrolysis and Bioactive Peptides
- Biofuel production and bioconversion
- Nanocomposite Films for Food Packaging
- Biopolymer Synthesis and Applications
- Seaweed-derived Bioactive Compounds
- Aquatic life and conservation
- Traditional Chinese Medicine Studies
- bioluminescence and chemiluminescence research
- Enzyme Catalysis and Immobilization
- Algal biology and biofuel production
- Advanced Drug Delivery Systems
- Microbial Metabolic Engineering and Bioproduction
- Cancer Research and Treatments
- Aquaculture Nutrition and Growth
- Food and Agricultural Sciences
- Bacteriophages and microbial interactions
- Enzyme-mediated dye degradation
- Advanced biosensing and bioanalysis techniques
- Genetic Associations and Epidemiology
- Polyamine Metabolism and Applications
- Travel-related health issues
- Coconut Research and Applications
- Microbial Fuel Cells and Bioremediation
Manipal Academy of Higher Education
2016-2025
National Institute of Technology Karnataka
2022
Abstract The practice of Ayurveda , the traditional medicine India, is based on concept three major constitutional types (Vata, Pitta and Kapha) defined as “ Prakriti ”. To best our knowledge, no study has convincingly correlated genomic variations with classification Prakriti. In present study, we performed genome-wide SNP (single nucleotide polymorphism) analysis (Affymetrix, 6.0) 262 well-classified male individuals (after screening 3416 subjects) belonging to Prakritis. We found 52 SNPs...
The development of chitinase tailored for the bioconversion chitin to oligosaccharides has attracted significant attention due its potential alleviate environmental pollution associated with chemical conversion processes. In this present investigation, we purified extracellular derived from marine Bacillus haynesii homogeneity and subsequently characterized it. molecular weight BhChi was approximately 35 kDa. displayed peak catalytic activity at pH 6.0, an optimal temperature 37 °C. It...
In the quest for sustainable fuel sources, chitin-based biorefineries are gaining recognition as chitin is second most abundant bioresource after cellulose. This approach not only provides an effective method converting shell waste from seafood processing into valuable bioethanol but also helps in management. this study, Bacillus haynesii, a marine isolate, was investigated and first report on optimisation of process parameters chitinase production haynesii. The One Factor at Time (OFAT)...
Abstract This study investigated the potential of tender coconut water as a natural alternative to potassium chloride (KCl) crosslink κ-carrageenan hydrogels. κ-Carrageenan hydrogels crosslinked with water, KCl, and their combination were formulated diclofenac sodium model drug, morphology, chemical bonding, compressive strength, uptake capacity, degradation resistance, cytotoxicity assessed. The results showed that crosslinking both KCl increased strength by up 450%, provided excellent...
The dwindling supply of the petroleum product and its carbon footprint has initiated search for a sustainable fuel alternate feed-stocks. One such underexplored feedstock is chitin, waste derived from sea food processing. limitation insolubility crystallinity inherent in chitin addressed with hydrolysates. In present study, chitinases producing marine isolate was isolated sediments Arabian Sea depth 20 m. order to increase expression chitinases, sequential optimisation using one factor at...
Abstract Chitosan, the deacetylated form of chitin, a natural polysaccharide, is known for its various biomedical applications. The present study aimed at exploring immunomodulatory properties chitosan (CSNP) and gallic acid‐grafted (cGANP) nanoparticles in mice model cyclophosphamide (CPA)‐induced immunosuppression. In addition, chitooligosaccharides, hydrolysed chitin chitosan, were also evaluated potential against immunosuppression mice. CPA (80 mg/kg/ip) induced significant...
The fourth generation of bioethanol production is on a lookout for non-lignocellulosic biomass waste. One such candidate chitin, the second most abundant biopolymer earth. However, crystalline nature chitin hinders its application potential production. This limitation can be circumvented by hydrolysing this polymer into oligomers using chitinases. We used hypothesis and isolated Bacillus haynesii, marine bacterium that utilizes colloidal as substrate produces oligosaccharides. Further, we...
Chitinases convert chitin into oligomers and are also known antifungal agents. Chitin have numerous industrial applications. However, chitin's crystalline nature requires pretreatment before breakdown oligomers. In the study, a novel marine bacterium Bacillus aryabhattai is isolated from Arabian Sea. Bacterial growth in different substrates like powder, flakes, colloidal confirmed chitinase presence could act upon insoluble with fractional release of The domain architecture analysis two...
Chitin deacetylase (CDA) (EC 3.5.1.41) is a hydrolytic enzyme that belongs to carbohydrate esterase family 4 as per the CAZY database. The CDA deacetylates chitin into chitosan. As marine ecosystem rich source of chitin, it would also hold unexplored extremophiles. In this study, an organism was isolated from 40 m sea sediment under halophilic condition and identified
Abstract There is a growing threat of wastewater pollution impacting human access to clean water. The surge in pharmaceuticals and personal care products (PPCPs) such water has reached alarming levels, posing an unprecedented aquatic ecosystems health. Conventional treatment not specifically tailored address the presence PPCPs. This paper examines possibility using nano-chitin chitosan as effective sustainable adsorbents for removal PPCPs from wastewater. recent progress functionalized or...
Abstract The study aimed to investigate the potential of low dose chitooligosaccharide (COS) in ameliorating dextran sodium sulfate (DSS) induced chronic colitis by regulating microbial dysbiosis and pro-inflammatory responses. Chronic was BALB/c mice DSS (4% w/v, 3 cycles 5 days) administration. were divided into four groups: vehicle, DSS, + mesalamine DSS+COS. COS administered orally, daily once, from day 1 30 at a 20 mg/kg 50 respectively. disease activity index (DAI), colon length,...