A5060441603- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Pleural and Pulmonary Diseases
- Lung Cancer Research Studies
- RNA modifications and cancer
- NF-κB Signaling Pathways
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Mechanisms and Therapy
- Hepatocellular Carcinoma Treatment and Prognosis
- Ubiquitin and proteasome pathways
- Liver Disease and Transplantation
- Genetic factors in colorectal cancer
- Genomics, phytochemicals, and oxidative stress
- Gastrointestinal Tumor Research and Treatment
- Epigenetics and DNA Methylation
- Molecular Biology Techniques and Applications
- Cholinesterase and Neurodegenerative Diseases
- Endometrial and Cervical Cancer Treatments
- Inflammatory Bowel Disease
- Cancer, Hypoxia, and Metabolism
- Phytochemistry and Bioactivity Studies
- Neurofibromatosis and Schwannoma Cases
- Peptidase Inhibition and Analysis
Henan Cancer Hospital
2022-2023
Zhengzhou University
2022-2023
Xi'an Chest Hospital
2022-2023
Kunming Medical University
2022
First Affiliated Hospital of GuangXi Medical University
2022
Guangxi Medical University
2022
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2022
Shanghai University of Traditional Chinese Medicine
2022
Peking University
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Clostridium butyricum (C. butyricum, CB) is a probiotic to modulate the intestinal disorders and CB supplement has been found have great impact on inflammation cancer treatment. However, effects mechanisms of colorectal (CRC) are not clear. We performed this study investigate influence progression CRC potential in vivo vitro.We established azoxymethane (AOM)/dextran sulfate sodium salt (DSS) model mice (male, 6-week-old C57BL/6J) divided them into control (Ctrl) groups at end second DSS...
Uniportal video-assisted thoracoscopic surgery (VATS) segmentectomy is widely used in the field of thoracic surgery. However, anatomical variations bronchi and lung vessels may be critical obstacles during precise pulmonary segmentectomy. Thus, it necessary to optimize uniportal VATS accurately identify plane between segments by precisely transecting blood segments. The indocyanine green fluorescence (ICGF)-based method has potential a feasible effective technique facilitate present study...
Mangrove-associated fungi are rich sources of novel and bioactive compounds. A total 102 fungal strains were isolated from the medicinal mangrove
Multiplatform molecular subtyping has been put into clinical practice as an alternative for The Cancer Genome Atlas (TCGA)-based classification endometrial cancer (EC), which proved a tool predicting prognosis and guiding treatment. traditional methods the of EC only based on pathological indicators are not accurate. present study aimed to classify level explored possibility one-time solution guide treatment determination by utilizing data from next-generation sequencing (NGS) panel....
Background: Linc00996 has been reported in a variety of malignant tumors, but its potential role and significance lung adenocarcinoma (LUAD) are not fully understood. The authors investigated the expression biological behavior LUAD elucidated function target genes. Materials methods: data cancers were derived from GEPIA. GEO TCGA datasets used to identify differential analyze respective correlation between different levels stage survival prognosis. We further processes pathways involved with...
Introduction Transformation from lung adenocarcinoma (LUAD) to small cell cancer (SCLC) is one of the mechanisms responsible for acquired EGFR-TKIs resistance. Although it rarely happens this event determines a rapid disease deterioration and needs specific treatment. Patient method We report case 75-year-old LUAD female with p.L858R mutation in Epidermal Growth Factor Receptor (EGFR) who presented SCLC transformation after responding first line osimertinib treatment only 6 months. To...
Lung cancer has the highest mortality rate among cancers worldwide, and most patients are diagnosed with non-small-cell lung (NSCLC), evaluating clinical efficacy of molecularly targeted therapy remains a major challenge.This paper retrospectively investigated outcome information 291 detected by next-generation sequencing (NGS) analysis fluorescence in situ hybridization (FISH), including 63 who were followed up. We analyzed epidermal growth factor receptor (EGFR) mutation abundance...
In our previous study, we developed a 4-hook claw-suture localization device for pulmonary nodule resection, which acheived satifisfactory results. Following this, conducted this single-center, open-label, randomized clinical trial to compare the success rate and complication of novel currently widely-used hookwire.Patients with small nodules (0.4-1 cm) who received preoperative thoracoscopic resection at Shanghai Chest Hospital were randomly assigned (1:2 ratio, via computer-generated...
156 Background: The current standard-of-care cancer screening paradigm is constrained to just a few types and has challenges in patient compliance due the invasive procedures endured from tests. Recently studies have demonstrated that blood-based multi-cancer detection (MCED) approaches may hold promise for identifying asymptomatic patients general population. However, most only exploit single aspect of hallmarks which challenging biological reasons since heterogenous disease with wide...
Background: Target therapies play more and important roles in gastrointestinal stromal tumors (GISTs) melanoma with the advancement of clinical drugs that overcome resistance caused by gene mutations. c-KIT mutations account for a large portion GIST patients, which are known to be sensitive or resistant tyrosine kinase inhibitors. However, role rare drug efficacy progression-free duration remains elusive. Methods: Two were identified using Sanger sequencing from cases. Cell experiments...