A5079023312- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Bacterial biofilms and quorum sensing
- Photoacoustic and Ultrasonic Imaging
- Antimicrobial agents and applications
- Advanced MRI Techniques and Applications
- Antimicrobial Peptides and Activities
- Nanocluster Synthesis and Applications
- Graphene and Nanomaterials Applications
- Medical Imaging Techniques and Applications
- Lanthanide and Transition Metal Complexes
Griffith University
2023-2024
The University of Queensland
2019
Australian Research Council
2019
Imaging agents that can be targeted to specific diseases and respond the microenvironment of diseased tissue are considerable interest due their potential in diagnosing managing diseases. Here we report a new class branched fluorinated glycopolymers as 19F MRI contrast reductive environment, for imaging cancer. The readily prepared by one-pot RAFT polymerization glucose- fluorine-containing monomers presence disulfide-containing cross-linking monomer. incorporation glucose units along...
We have developed a novel pH-responsive delivery system consisting of oleylamine-modified polysuccinimide (PSI) nanoparticles (NPs) whereby NPs remained stable and started to release bioactive agents after 8.5 h with maximal acquired 36 under physiological pH. Our did not exhibit any burst drug, which is key advantage in anti-cancer targeted drug system. Here, the function as carrier for such Curcumin IR-780 dye former exerts its intrinsic abilities, latter confers photothermal treatment...
Nanophotothermal therapy based on nanoparticles (NPs) that convert near-infrared (NIR) light to generate heat selectively kill cancer cells has attracted immense interest due its high efficacy and being free of ionizing radiation damage. Here, for the first time, we have designed a novel nanohybrid, silver-iron oxide NP (AgIONP), which was successfully tuned strong absorbance at NIR wavelengths be effective in photothermal treatment dual-imaging strategy using MRI photoacoustic imaging (PAI)...
We explored the feasibility of a self-assembled chitosan nanocomposite incorporating cerium oxide/nanoceria and superparamagnetic iron oxide nanoparticles (Chit-IOCO NPs), conjugated with methotrexate (MTX) Cy5 dye, as an integrated cancer theranostic nanosystem (Chit-IOCO-MTX-Cy5). In this system, nanoceria serves anti-cancer agent, while function negative contrast agent for MR imaging. This dual metal is MTX which structural analogue folate, serving both targeting mechanism folate...
ABSTRACT Antimicrobial polymers have been widely reported to exert strong biocidal effects against bacteria. In contrast with antimicrobial aliphatic ammonium groups, anilinium groups rarely studied and applied as materials. this study, a representative polymer aniline side functional poly( N , ‐dimethylaminophenylene methacrylamide) (PDMAPMA), was explored novel polymer. PDMAPMA synthesized its physicochemical properties evaluated. The methyl iodide‐quaternized tested the Gram‐positive...