James Muir

ORCID: 0000-0003-3540-0891
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Marine and fisheries research
  • Aquaculture Nutrition and Growth
  • Marine Bivalve and Aquaculture Studies
  • Fish Biology and Ecology Studies
  • Fisheries and Aquaculture Studies
  • Fish Ecology and Management Studies
  • Neuroscience and Neuropharmacology Research
  • Carbon Dioxide Capture Technologies
  • Chemical Looping and Thermochemical Processes
  • Metal Forming Simulation Techniques
  • Coastal and Marine Management
  • Catalysts for Methane Reforming
  • Agricultural Systems and Practices
  • Agriculture Sustainability and Environmental Impact
  • Canadian Identity and History
  • Water Quality Monitoring Technologies
  • Food Waste Reduction and Sustainability
  • Agricultural Innovations and Practices
  • Organic Food and Agriculture
  • Microstructure and Mechanical Properties of Steels
  • Photoreceptor and optogenetics research
  • American Constitutional Law and Politics
  • Coral and Marine Ecosystems Studies
  • Food Industry and Aquatic Biology
  • Metallurgy and Material Forming

Cytel (United States)
2023

DairyNZ
2018

University College London
2009-2016

University of Alberta
2016

University of Winnipeg
2009-2014

Gloucestershire Royal Hospital
2013

University of Stirling
2000-2012

University of Technology Sydney
2004

Environmental Resources Management (United Kingdom)
1999

Sandia National Laboratories
1987-1994

Energy use, mainly to reverse ion movements in neurons, is a fundamental constraint on brain information processing. Trafficking of mitochondria locations neurons where there are large fluxes essential for powering neural function. Mitochondrial trafficking regulated by Ca2+ entry through ionotropic glutamate receptors, but the underlying mechanism unknown. We show that protein Miro1 links KIF5 motor proteins, allowing move along microtubules. This linkage inhibited micromolar levels binding...

10.1016/j.neuron.2009.01.030 article EN cc-by Neuron 2009-02-01

Although food prices in major world markets are at or near a historical low, there is increasing concern about security-the ability of the to provide healthy and environmentally sustainable diets for all its peoples. This article an introduction collection reviews whose authors were asked explore drivers affecting system between now 2050. A first set papers explores main factors demand (population growth, changes consumption patterns, effects on urbanization importance understanding income...

10.1098/rstb.2010.0180 article EN cc-by Philosophical Transactions of the Royal Society B Biological Sciences 2010-08-16

This paper explores consumer understanding and perception of organic food, with specific reference to the relatively new concept farmed salmon. Key themes associated term “organic” its meaning, as determined by consumers, are explored role labelling regulatory authorities considered. Focus groups in five countries (UK, Germany, Spain, Norway France) consisting 196 participants showed that most consumers confused about meaning largely unaware certification process. Many were unsure, even...

10.1108/00070700410516784 article EN British Food Journal 2004-02-01

Abstract Copy number variation (CNV) at the 15q11.2 region has been identified as a significant risk locus for neurological and neuropsychiatric conditions such schizophrenia (SCZ) autism spectrum disorder (ASD). However, individual roles genes this in nervous system development, function connectivity remain poorly understood. Haploinsufficiency of one gene region, Cyfip1 , may provide model CNV-associated phenotypes. Here we show that altering CYFIP1 expression levels neurons both vitro...

10.1038/tp.2014.16 article EN cc-by Translational Psychiatry 2014-03-25

Modification of the number GABA A receptors (GABA Rs) clustered at inhibitory synapses can regulate synapse strength with important implications for information processing and nervous system plasticity pathology. Currently, however, mechanisms that Rs remain poorly understood. By imaging superecliptic pHluorin tagged R subunits we show synaptic clusters are normally stable, but increased neuronal activity upon glutamate receptor (GluR) activation results in their rapid reversible dispersal....

10.1073/pnas.1000589107 article EN Proceedings of the National Academy of Sciences 2010-09-07

Within the overall agro-based economy in Bangladesh, freshwater prawn (Macrobrachium rosenbergii) farming is currently one of most important sectors national economy. During last two decades, its development has attracted considerable attention for export potential. Freshwater offers diverse livelihood opportunities a large number rural poor. Although prospects are positive, it requires some research and activities long-term sustainability. This paper provides an overview Bangladesh.

10.1111/j.1365-2109.2008.01931.x article EN Aquaculture Research 2008-03-25

The astrocytic GLT‐1 (or EAAT2) is the major glutamate transporter for clearing synaptic glutamate. While diffusion dynamics of neurotransmitter receptors at neuronal surface are well understood, far less known regarding trafficking transporters in subcellular domains astrocyte membrane. Here, we have used live‐cell imaging to study mechanisms regulating astrocytes dissociated and brain slice cultures. Using GFP‐time lapse imaging, show that forms stable clusters dispersed rapidly reversibly...

10.1002/glia.22997 article EN cc-by Glia 2016-05-17

Aquaculture has been one of the most rapid and technically innovative food production sectors globally, with significant investment, scientific technical development growth in many parts world over past two decades. While this had a effect on global supply aquatic products an important impact rural urban employment developing economies, increasing internationalization not without concern for natural resource use, environmental social disruption. The expectations diversification are now while...

10.1098/rstb.2004.1572 article EN Philosophical Transactions of the Royal Society B Biological Sciences 2005-01-29

The strength of synaptic inhibition depends partly on the number GABA(A) receptors (GABA(A)Rs) found at sites. trafficking GABA(A)Rs within endocytic pathway is a key determinant surface GABA(A)R and altered in neuropathologies, such as cerebral ischemia. However, molecular mechanisms signaling pathways that regulate this are poorly understood. Here, we report subunit specific lysosomal targeting GABA(A)Rs. We demonstrate into degradation facilitated by ubiquitination motif intracellular...

10.1073/pnas.0905502106 article EN Proceedings of the National Academy of Sciences 2009-10-07

The axon initial segment (AIS), a site of action potential initiation, undergoes activity-dependent homeostatic repositioning to fine-tune neuronal activity. However, little is known about the behavior GABAA receptors (GABAARs) at synapses made onto and especially AIS. Here, we study clustering lateral diffusion GABAARs in AIS under baseline conditions, find that GABAAR mobility lower than dendrites. We differences axonal between containing α1 or α2 subunits, which are localize...

10.3389/fncel.2014.00151 article EN cc-by Frontiers in Cellular Neuroscience 2014-06-10

The strength of synaptic inhibition can be controlled by the stability and endocytosis surface GABA A receptors (GABA Rs), but receptor dynamics that underpin R recruitment to dendritic endocytic zones (EZs) have not been investigated. Stabilization Rs at EZs is likely regulated interactions with clathrin-adaptor AP2, molecular determinants these associations remain poorly understood. Moreover, although downmodulation plays a key role in pathological disinhibition conditions such as ischemia...

10.1523/jneurosci.1622-11.2011 article EN cc-by-nc-sa Journal of Neuroscience 2012-02-14

10.1016/s0048-9697(99)00281-8 article EN The Science of The Total Environment 1999-09-01

Abstract A conceptual framework, drawn from an approach to poverty reduction known as the sustainable livelihoods (SLA), is applied understanding role of freshwater prawn, Macrobrachium rosenbergii , farming in gher (modified rice fields with high, broad peripheral dikes) systems southwest Bangladesh. Gher potentially allows incorporation a wide variety crops together fish, dike crops, and culture. The analysis shows how, context, are achieved through access range livelihood assets, which...

10.1111/j.1749-7345.2008.00198.x article EN Journal of the World Aquaculture Society 2008-09-21

Globally, dairy farmers face issues with attracting and retaining high-quality staff. In the present study, a qualitative research method was used to explore current challenges in relation people on farm, approaches currently by make dairying more attractive productive for people, perspectives future farms. Current were areas of recruitment, productivity, skills learning, farm industry structural issues, impact profitability ability implement new practices. Participants’ vision workplace one...

10.1071/an18568 article EN Animal Production Science 2018-11-22
Coming Soon ...