A5061789335- Evolution and Genetic Dynamics
- Genetic diversity and population structure
- Plant and animal studies
- Ecology and Vegetation Dynamics Studies
- Insect and Arachnid Ecology and Behavior
- Ionosphere and magnetosphere dynamics
- Animal Ecology and Behavior Studies
- Species Distribution and Climate Change
- Evolutionary Game Theory and Cooperation
- COVID-19 epidemiological studies
- Lepidoptera: Biology and Taxonomy
- Solar and Space Plasma Dynamics
- Evolution and Paleontology Studies
- Animal Behavior and Reproduction
- Earthquake Detection and Analysis
- Geomagnetism and Paleomagnetism Studies
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Vectors
- Magnetic confinement fusion research
- Insect and Pesticide Research
- Evolutionary Algorithms and Applications
- Mathematical and Theoretical Epidemiology and Ecology Models
- Plasma Diagnostics and Applications
- Power System Optimization and Stability
- SARS-CoV-2 detection and testing
Hokkaido University
2019-2025
University of Tokyo Hospital
2025
University of British Columbia
2022-2024
Tokyo Metropolitan University
2017-2022
Kyushu University
2002-2020
Google (United States)
2017
The Institute of Statistical Mathematics
2004
Abstract Speciation research—the scientific field focused on understanding the origin and diversity of species—has a long complex history. While relevant to one another, specific goals activities speciation researchers are highly diverse, scattered across collection different perspectives. Thus, our will benefit from efforts bridge findings diverse people who do work. In this paper, we outline two ways integrating research: (i) integration, through bringing together ideas, data, approaches;...
Abstract Biological diversification often includes burst of lineage splitting. Such “radiation” has been known to act as evolutionary arenas with the potential generate unique phylogenetic clusters and further novel groups. Although these radiations when accompanied by ecological diversification, so‐called “adaptive radiation” have persisted a central premise in biology, genetic mechanism such rapid remained unclear. There are several critical definitions for pattern adaptive radiation,...
Abstract Background Ensitrelvir is a novel SARS-CoV-2 3-chymotrypsin-like protease inhibitor, similar to nirmatrelvir/ritonavir. Several case reports have demonstrated the efficacy of inhibitors in treating prolonged coronavirus disease 2019 (COVID-19) immunocompromised patients. Tacrolimus (TAC) widely used immunosuppressive agent whose blood level can increase significantly due inhibition cytochrome P450 3A (CYP3A) and P-glycoprotein by Since ensitrelvir also inhibits CYP3A P-gp,...
Population genomic analysis of hybrid zones is instrumental to our understanding the evolution reproductive isolation. Many temperate are formed by secondary contact between two parental populations that have undergone postglacial range expansion. Here, we show explicitly accounting for historical isolation followed expansion prior fundamental explaining genetic and fitness patterns in these zones. Specifically, ancestral population can result allele surfing, where neutral or slightly...
Allopatric speciation is a mechanism to evolve reproductive isolation; it caused by the accumulation of genetic differences between populations while they are geographically isolated. Here, we studied simple stochastic model for time until geographical isolation in fragmented that experience recurrent but infrequent migration subpopulations. We assumed mating incompatibility controlled number loci behave as neutral characters novel mutations within each population. Genetic distance was...
The formation of new species via the accumulation incompatible genetic changes is thought to result either from ecologically based divergent natural selection or order by which mutations happen arise, leading different evolutionary trajectories even under similar pressures. There growing evidence in support both ecological speciation and mutation-order speciation, but how environmental scenarios affect rate remains underexplored. We use a simple model optimizing on multiple traits ("Fisher's...
Abstract The origin and patterns of species diversity are fundamental themes in ecology evolutionary biology. Insular systems play an important role biogeography, the richness within insular system has classically been considered as determined by balance between rate speciation plus net migration extinction. A recent wave studies integrating comprehensive phenotypic, phylogenetic, environmental data is accumulating additional macroevolutionary insights at unprecedented scales. In this...
In a substorm event of August 14, 1996, the Geotail satellite was at X GSM ∼ −10 R E aligned with GOES 8 in direction premidnight sector. Two Pi2 onsets were identified. Whereas first onset associated pseudobreakup, an auroral bulge developed following second onset. At pseudobreakup observed fast (>900 km/s) plasma flow along dipolarization, but geosynchronous magnetic field became stretched subsequently. contrast, for main onset, dipolarized 8, although total (time‐integrated) transport...
Abstract During the COVID-19 pandemic, human behavior change as a result of nonpharmaceutical interventions such isolation may have induced directional selection for viral evolution. By combining previously published empirical clinical data analysis and multi-level mathematical modeling, we find that SARS-CoV-2 variants selected virus evolved from pre-Alpha to Delta variant had earlier higher peak in load dynamics but shorter duration infection. Selection increased transmissibility shapes...
The present study seeks to systematically examine the fast plasma flow in sheet at geomagnetically quiet time. uses measurements made by Geotail satellite midnight sector x > −50 R E during intervals with a total duration of 446 hours. Comparison results previous studies suggests that occurrence frequency perpendicular velocity depends more clearly on radial distance than geomagnetic activity. Two extreme events were selected for detailed studies; they occurred 23 November and 10–11...
Many researchers have studied the population dynamics of microbe microbes as a typical example dynamics. The Monod equation, which mainly focuses on growth and stationary phases, is used when plotting curve. However, potential in late stage culture has been overlooked. Previous studies considered direct degradation products to limiting substrate. In this study, we microbial during phase, enables us describe precisely. were divided into two populations: one grew by consuming substrate other...
Genetic divergence among allopatric populations builds reproductive isolation over time. This process is accelerated when face a changing environment that allows large-effect mutational differences to accumulate, but abrupt change also places at risk of extinction. Here we use simulations Fisher's geometric model with explicit population dynamics explore the genetic changes occur in environmental changes. Because evolutionary rescue leads fixation mutations whose phenotypic effects are...
We studied the time to speciation by geographical isolation for a species living on three islands connected rare migration. assumed that incompatibility was controlled number of quantitative loci and individuals differing in more than threshold did not mix genetically with each other. For locus, we defined configuration (GC), which specifies common alleles, traced stochastic transitions between different GCs. From these results, calculated changes genetic distances. As single migration event...
Abstract Many consequences of reproductive interference have important implications in biodiversity conservation policy. After briefly summarizing our comments on the articles this special feature, we focus role speciation due to geographic isolation with only infrequent migration between islands (or island‐like habitats). As two isolated populations accumulate incompatible genes, they became genetically distinct. When a rare occurs from one island other, greatly affects its outcome. A paper...
Abstract Costly heterospecific mating interactions, such as hybridization, select for prezygotic reproductive isolation. One of the potential traits responding to selection arising from maladaptive hybridization is habitat preference, whose divergence results in interspecific segregation. Theoretical studies have so far assumed that preference a sexually shared trait. However, male and female preferences can experience different pressures. Here, by combining analytical simulation approaches,...
Viruses evolve in infected host populations, and population dynamics affect viral evolution. RNA viruses with a short duration of infection high peak load, such as SARS-CoV-2, are maintained human populations. By contrast, characterized by long low load (e.g., borna disease virus) can be nonhuman the process evolution persistent has rarely been explored. Here, using multi-level modeling approach including both individual-level virus population-scale transmission, we consider based on...
The present study observationally examines relationship between Pi2 pulsations and the bursty bulk flow (BBF) in plasma sheet. At a onset of August 14, 1996, GEOTAIL satellite GOES8 geosynchronous were aligned X direction observing transient signatures. Those signatures examined by referring to ground low‐latitude wave detected at same meridian as GOES8. In event, BBF started prior onset, but it was preceded It is also found that correlated much better with than perturbations sheet velocity...
The present study investigates the energy storage and release processes of substorms as a function both position substorm intensity in model‐independent manner. As an index intensity, we use amplitude positive bay observed at middle low latitudes. magnetotail, total pressure measured by Geotail. We have performed superposed epoch analysis for each group binned terms intensity. found that (1) magnitude increasing rate (i.e., density) near‐tail region (−15 R E < X GSM −6 −8 Y <8 ) are...