A5068062957- Toxin Mechanisms and Immunotoxins
- Research on Leishmaniasis Studies
- Atherosclerosis and Cardiovascular Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Vector-borne infectious diseases
- Trypanosoma species research and implications
Universitat Autònoma de Barcelona
2018-2022
Universidad de la República
2013
Hospital de Clínicas
2013
The effect of Leishmania infantum soluble antigen (LSA) and recombinant Kinetoplastid Membrane Protein 11 (rKMP11) on the induction ex vivo specific IFN-γ (n = 69) antibody responses 108) was determined in dogs. All dogs were tested for serological response to both antigens divided into Group 1: healthy (Asturias, Spain, n 26), 2: sick 46), 3: Ibizan hounds (Mallorca, 22) 4: (Bari, Italy, 14). Antibody levels higher LSA when compared rKMP11 (p 0.001). all seronegative 18% low seropositive...
Activation of toll-like receptors (TLRs) has been shown to play an important role in leishmaniosis by enhancing the parasite specific immune responses control infection. However, TLR agonists not studied detail dogs. The aim this study was determine effect TLR3, TLR4, and TLR7 (TLR3a, TLR4a, TLR7a) alone or combination with Leishmania infantum antigen (LSA) on TNF- α IL-6 production blood from dogs living endemic areas canine (CanL). Twenty-four healthy Catalonia (n=14) Ibizan hound island...
Tobacco use is a major risk factor for heart attacks, strokes, chronic obstructive pulmonary disease (COPD), emphysema, and cancer. Smoking promotes inflammation thrombosis through poorly understood mechanism. Whether if the immune response significantly affected by smoking not well established. We studied different leukocytes subpopulations its activation flow cytometry, in very characterized population of healthy subjects. With previous authorization Ethics Committees institution signed...