This study evaluates a new collagen matrix that is designed with bilayered structure in order to promote guided tissue regeneration and integration within the host tissue. material induced mild reaction when assessed murine model was well integrated tissue, persisting implantation bed throughout vivo study. A more porous layer rapidly infiltrated by mesenchymal cells, while be barrier allowed cell attachment integration, but at same time remained impermeable invading cells for first 30 days...

The aim of this study was to investigate in vitro the cytotoxicity and antibacterial properties four different endodontic sealers using human periodontal ligament fibroblast cell proliferation visual analysis growth inhibition. A silicone (GuttaFlow), silicate (EndoSequence BC), zinc oxide eugenol (Pulp Canal Sealer EWT) epoxy resin (AH Plus Jet) based sealer were incubated with PDL fibroblasts (104 cells/ml, n = 6) up 96 h. Cell (RFU) determined by means Alamar Blue assay. morphology...

Irrigant usage information in relation to years of professional experience was collected from general dentists different German federal states by means a questionnaire.A short survey concerning endodontic treatment and use irrigants mailed 4240 or delivered 3720 dental offices as an extra page journal eight states. Detailed the most frequently used irrigants, their concentrations, spectrum disinfectants root canal concepts for vital nonvital pulps, main topics continuing education well...

Over the last years, electronic cigarettes (ECs) have become more popular, particularly in individuals who want to give up smoking tobacco. The aim of present study was assess influence different e-smoking liquids on viability and proliferation human periodontal ligament fibroblasts.For this six test solutions with components from ECs were selected: lime-, hazelnut- menthol-flavored liquids, nicotine, propylene glycol, PBS as control group. fibroblasts incubated 96 h cell measured by using...

The aim of the study was to compare two frequently used dental age estimation methods for accuracy. A total 479 panoramic radiographs in groups 6–14 years from a German population were evaluated. 268 boys and 211 girls assessed by means method Demirjian (1973) Cameriere (2006) compared with their actual chronological age. Demirjan's showed an overestimation all (mean difference −0.16, p = 0.010, range −0.35 0.09), group 9 underestimation. Using same −0.18, 0.008, −0.45 0.13), could also be...

Osteoinductive bone substitutes are defined by their ability to induce new formation even at heterotopic implantation sites. The present study was designed analyze the potential osteoinductivity of two different substitute materials in caprine muscle tissue.One gram each either a porous beta-tricalcium phosphate (β-TCP) or an hydroxyapatite/silicon dioxide (HA/SiO2)-based nanocrystalline material implanted several pouches goats. biomaterials were explanted 29, 91 and 181 days after...

Objective: To analyze Mucograft®(MG), a recently introduced collagen matrix, in vitro and vivo, compare it with BioGide®(BG), well-established membrane, as control. Material Methods: A detailed analysis of the materials surface ultra-structure was performed. Cellular growth patterns proliferation rates human fibroblasts on MG BG were analyzed vitro. In addition, early tissue reaction CD-1 mouse to these by means histological histomorphometrical analysis. Results: showed three-fold higher...

Introduction Percutaneous balloon valvuloplasty is the treatment of choice for critical pulmonary valve stenosis (CPS) and atresia with intact ventricular septum (PA/IVS) if ventricle has a suitable size. This study aimed to evaluate long-term outcomes predictors surgical intervention replacement in patients CPS or PA/IVS after PBV, considering different morphological hemodynamic parameters. Methods Neonates who were admitted University Medicine Mainz Hospital Erlangen between November 1994...

Platelet-rich fibrin (PRF) is a blood concentrate derived from venous that processed without anticoagulants by one-step centrifugation process. This three-dimensional scaffold contains inflammatory cells and plasma proteins entrapped in matrix. Liquid-PRF was developed based on the previously described low-speed centrifuge concept (LSCC), which allowed introduction of liquid-PRF formulation fibrinogen thrombin prior to its conversion fibrin. introduced meet clinical demand for combination...

Occurrence of open dentinal tubules as a cause dental hypersensitivity is very common pnenomenon in patients. The aim this vitro study was to assess the effect silver diamine fluoride solution (Ag(NH3)2 F) on human dentin samples.A total five fully retained wisdom teeth were selected for study. crowns separated from roots and occlusal enamel surface removed. All samples treated 60 seconds with phosphoric acid (36%) rinsed thoroughly remove smear layer. Then desensitizing agent (Riva Star,...

The clinical suitability of a bone substitute material is determined by the ability to induce tissue reaction specific its composition. aim this in vivo study was analyze silica matrix-embedded, nanocrystalline hydroxyapatite substitute.The subcutaneous implantation model Wistar rats chosen assess effect degradation on vascularization biomaterial and biodegradation within time period 6 months. Already at day 10 after implantation, histomorphometrical analysis showed that bed reached peak...

ABSTRACT Purpose: In this study the de novo bone formation capacity of a nanocrystalline hydroxyapatite substitute was assessed 3 and 6 months after its insertion into human sinus cavity. Materials Methods: Sinus cavity augmentation performed in total 14 patients ( n = 7 implantation months; months) with severely atrophic maxillary bone. The specimens obtained were analyzed histologically histomorphometrically special focus on metabolism within residual augmented region. Results: This...

Abstract Objectives In this study, the efficacy of a miswak extract‐containing toothpaste ( Salvadora persica ) on gingival inflammation was compared with that herbal and conventional toothpaste. Methods Non‐smoking outpatients sulcus bleeding index SBI ≥25% periodontal pocket depths ≤3 mm were randomly selected divided into three groups: M‐group, toothpaste; P‐group, C‐group, After instructing patients to brush their teeth twice day for 3 weeks assigned using flat‐trimmed manual toothbrush,...

Abstract Objectives This study aimed to establish a fully digital measurement protocol for standardizing the description of hard palate and cleft morphology in neonates with an isolated (CPO) Pierre Robin sequence (PRS). Materials Methods A total 20 digitized plaster models CPO PRS were retrospectively investigated. For control group, was segmented from 21 pre‐existing 1.5 T MRI datasets exported as STL file. The marked predefined reference points by three raters. Distance, angular, area...

The aim of this study was to clinically assess the capacity a novel bovine pericardium based, non-cross linked collagen matrix in root coverage.

The aim of this study was to determine the presence matrix metalloproteinase-8 in gingival crevicular fluid (GCF) patients after acute myocardial infarction (AMI).A total 48 GCF samples from 20 AMI patients, hospitalized at Department Cardiology and Angiology Johannes Gutenberg University Mainz, were investigated. Besides all suffered chronic periodontal disease. Fifty-one healthy age matched individuals with similar conditions served as controls. dental examination included assessment oral...