A5025601740- Gout, Hyperuricemia, Uric Acid
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Chronic Kidney Disease and Diabetes
- Liver Disease Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Blood Pressure and Hypertension Studies
- Diet, Metabolism, and Disease
- Advanced Chemical Sensor Technologies
- Nutrition and Health in Aging
- Cardiovascular Health and Disease Prevention
- Clinical Nutrition and Gastroenterology
- Adrenal Hormones and Disorders
- Body Composition Measurement Techniques
- Renal and Vascular Pathologies
- Folate and B Vitamins Research
- Hormonal Regulation and Hypertension
- Exercise and Physiological Responses
- Alcohol Consumption and Health Effects
- Lipoproteins and Cardiovascular Health
- Gold and Silver Nanoparticles Synthesis and Applications
- Heterotopic Ossification and Related Conditions
- Bone health and osteoporosis research
- Radiomics and Machine Learning in Medical Imaging
Pusan National University Yangsan Hospital
2014-2025
Pusan National University
2010-2024
Shanghai Sixth People's Hospital
2018
Army Medical University
2013-2016
Southwest Hospital
2013
Purpose: Muscles play an important role in energy metabolism. Several studies have investigated the association between muscle mass and metabolic syndrome (MetS), reporting conflicting results. However, concerning strength MetS are limited. We aimed to investigate relative handgrip (HGS) Korean adults. Participants methods: analyzed data from 5,014 adults aged ≥20 years (2,472 men 2,542 women) who participated Korea National Health Nutrition Examination Survey (KNHANES) VI (2014–2015)....
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic worldwide, and it hepatic manifestation of metabolic syndrome (MetS). We aimed to estimate prevalence NAFLD defined by index (FLI), in order investigate association between FLI disorders determine cutoff value screen for MetS.This study utilized a national representative sample Korean adults (the National Health Nutrition Examination Surveys) which was conducted 2010-2011. A total 10,107 aged 19 years or older were selected....
The cardiovascular (CV) benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i) are well established, but their effects on lower limb events (LLEs) remain inconclusive, with conflicting findings from clinical trials and real-world studies. This study aimed to assess the risks CV LLEs associated SGLT2i compared dipeptidyl peptidase-4 (DPP-4i) in patients type diabetes. included diabetes who were newly prescribed or DPP-4i using data National Health Insurance Service South Korea. A 1:1...
Vascular calcification refers to the deposition of calcium phosphate in cardiovascular tissues, including arteries and myocardium. is frequently associated with disease. Recently, bone morphgenetic protein-7 (BMP-7) has been proposed play an inhibitory role vascular calcification, but its effect not fully elucidated. We therefore tested hypothesis that BMP-7 inhibits by using two conditions, high levels vitamin D phosphate, each which could enhance calcification. C57BL/6 mice were treated...
Purpose: Providing continuous self-care support to the growing diabetes population is challenging.Strategies are needed enhance engagement in self-care, utilizing innovative technologies for personalized feedback.This study aimed assess feasibility of Automated Personalized Self-Care program among type 2 patients and evaluate its preliminary effectiveness. Methods: A parallel randomized pilot trial with qualitative interviews occurred from May 3, 2022, September 27, 2022.Participants aged...
The present study investigated the role of synergistic interaction between hyperuricemia and abdominal obesity as a risk factor for components metabolic syndrome.We performed cross-sectional using data 16,094 individuals from seventh Korean National Health Nutrition Examination Survey (2016 to 2018). adjusted odds ratios syndrome its were analyzed by multivariate logistic regression analysis. presence was evaluated calculating additive scales-the relative excess due interaction, attributable...
Diabetes and its complications affect the younger population are associated with a high mortality rate; however, early diagnosis can contribute to selection of appropriate treatment regimens that reduce mortality. Although diabetes via exhaled breath has great potential for diagnosis, research on such is restricted disease detection, requiring in-depth examination diagnose classify diseases their complications. This study demonstrates use an artificial neural processing-based bioelectronic...
Objective This study investigated the association between relative hand grip strength (HGS) and glycemic status, such as impaired fasting glucose (IFG) diabetes, using data from Korea National Health Nutrition Examination Survey (KNHANES). Methods We performed a cross-sectional KNHANES of 27,894 individuals 2014 to 2019. Relative HGS was defined absolute divided by body mass index into quartiles in men women. Odds ratios (OR) for diabetes IFG were calculated multivariate logistic regression...
Context -Non-alcoholic fatty liver disease (NAFLD), hepatic manifestation of metabolic syndrome, has been considered the most common nowadays, which is also frequent cause elevated transaminases and cryptogenic cirrhosis.The greatest input acids into consequent increased beta-oxidation contribute to formation free radicals, release inflammatory cytokines varying degrees hepatocytic aggression, whose histological expression may vary from steatosis (HS) non-alcoholic steatohepatitis (NASH).The...
The ratio of estimated glomerular filtration rate (eGFR) based on cystatin C and creatinine (eGFRcystatin C/eGFRcreatinine ratio) is related to accumulating atherosclerosis-promoting proteins increased mortality in several cohorts.We assessed whether the eGFRcystatin a predictor arterial stiffness sub-clinical atherosclerosis type 2 diabetes mellitus (T2DM) patients, who were followed up during 2008 2016. GFR was using an equation creatinine.A total 860 patients stratified according their...
Background Obesity is a major worldwide health problem and can be related to cellular senescence. Along with the rise in obesity, comorbidity of renal ischemia-reperfusion (IR) injury increasing. Whether obesity accelerates severity IR whether senescence contributes these conditions remain unclear. We studied degree kidneys perirenal adipose tissues high-fat-diet–induced obese mice. Methods C57BL/6 mice fed standard chow or high-fat diet for 16 weeks were randomized sham group (n = 6–10...
Apolipoprotein A-II (apoA-II) is the second-most abundant apolipoprotein in human high-density lipoprotein and its role cardio metabolic risk not entirely clear. It has been suggested to have poor anti-atherogenic or even pro-atherogenic properties, but there are few studies on possible of apoA-II Asian populations. The aim this study evaluate syndrome (MetS) compared with A-I (apoA-I) B (apoB) Korean adults.We analyzed data from 244 adults who visited Center for Health Promotion Pusan...
Background.The aim of this study was to identify clinical risk factors associated with the development albuminuria and renal impairment in patients type 2 diabetes (T2D).In addition, we evaluated if different equations estimate function had an impact on interpretation data.This done a nationwide population-based using data from Swedish National Diabetes Register.Methods.Three thousand six hundred sixty-seven T2D aged 30-74 years no signs dysfunction at baseline (no eGFR >60 mL/min/1.73m...
To investigate the association between serum uric acid (UA) and relative hand grip strength (HGS) in comparison with metabolic syndrome components.We analyzed data of 5247 Korean adults aged ≥ 20 years (2422 men 2825 women) who participated KNHNES VII (2018).Among women, HGS was significantly lower participants hyperuricemia (1.65 ± 0.04) than those without (1.95 0.01) decreased highest quartile (4Q: 1.77 0.02) UA compared that lowest (1Q: 1.98 0.02). Among men, (3.09 0.04 vs. 3.16 4Q (3.08...
Serum cystatin C has been known as a novel marker of preclinical renal dysfunction, and higher levels are associated with increased risks hip nonvertebral fractures. However, there few reports on the association between serum bone mineral density (BMD), especially in Asian population. We evaluated BMD spine Korean adults.A cross-sectional study was performed 865 adults (325 men 540 women) who participated comprehensive medical examination program underwent densitometry. Renal function...
The global shortage of glucagon-like peptide-1 (GLP-1) receptor agonists, which are highly sought after as treatments for type 2 diabetes and obesity, is increasing. This deficit attributed to the unexpected increase in demand GLP-1 agonists. has caused significant harm patients with mellitus who already using agonists blood sugar management, weight loss, or reduction cardiovascular risk those looking start. To address this situation, doctors need adjust medications considering patient...
Abstract Context With rising the prevalence of type 2 diabetes mellitus (T2DM) and prediabetes, importance 1-hour post-load plasma glucose (1-h PG) for early hyperglycemia screening is emphasized. Objective This study investigates utility 1-h PG in predicting T2DM adults with normal fasting (FPG) levels. Methods 7,504 participants were categorized into three groups: tolerance (NGT) < 155 mg/dL, NGT ≥ impaired (IGT). Insulin sensitivity secretion indices compared between groups at...