- Maternal Mental Health During Pregnancy and Postpartum
- Breastfeeding Practices and Influences
- Circadian rhythm and melatonin
- Pregnancy and Medication Impact
- Reproductive Health and Technologies
- Sleep and related disorders
- Gestational Diabetes Research and Management
- Child and Adolescent Psychosocial and Emotional Development
- Reproductive Health and Contraception
- Digital Transformation in Industry
- Biomedical and Engineering Education
- Mobile Health and mHealth Applications
- Attachment and Relationship Dynamics
- Prenatal Substance Exposure Effects
- Restraint-Related Deaths
- Child Abuse and Related Trauma
- Homicide, Infanticide, and Child Abuse
- Maternal and Perinatal Health Interventions
- Adolescent Sexual and Reproductive Health
- Ocular Disorders and Treatments
- Congenital heart defects research
- Obstructive Sleep Apnea Research
- Fetal and Pediatric Neurological Disorders
- Craniofacial Disorders and Treatments
- Anatomy and Medical Technology
Erasmus MC
2015-2025
Erasmus University Rotterdam
2016-2025
Amsterdam University Medical Centers
2022
University of Amsterdam
2022
Netherlands Forensic Institute
2015-2016
Amsterdam UMC Location University of Amsterdam
2016
Digital reconstruction of human development The detailed morphology has intrigued scientists and the medical field alike. However, scarcity specimens hampers mapping tissue architecture. Furthermore, inaccuracies in description have crept into textbooks from observations animal models that are extrapolated to humans. By normal developmental processes patterns, such as growth relative placement organs, congenital anomalies can be better understood. de Bakker et al. generated interactive...
A digital twin (DT), originally defined as a virtual representation of physical asset, system, or process, is new concept in health care. DT care not single technology but domain-adapted multimodal modeling approach incorporating the acquisition, management, analysis, prediction, and interpretation data, aiming to improve medical decision-making. However, there are many challenges barriers that must be overcome before can used In this viewpoint paper, we build on current literature, address...
Depression during pregnancy is a common and high impact disease. Generally, 5–10 % of pregnant women suffer from depression. Children who have been exposed to maternal depression higher risk adverse birth outcomes more often show cognitive, emotional behavioural problems. Therefore, early detection treatment antepartum necessary. Both psychotherapy antidepressant medication, first choice treatments in non-pregnant population, limitations treating pregnancy. it urgent relevant investigate...
Objectives Approximately 11%–13% of pregnant women suffer from depression. Bright light therapy (BLT) is a promising treatment, combining direct availability, sufficient efficacy, low costs and high safety for both mother child. Here, we examined the effects BLT on depression during pregnancy. Design Randomised, double-blind controlled trial. Setting Primary secondary care in The Netherlands, November 2016 to March 2019. Participants 67 (12–32 weeks gestational age) with DSM-5 diagnosis...
To increase our understanding of the etiology specific neurological disorders (e.g., Duane syndrome, glossoptosis in Pierre Robin sequence), proper knowledge anatomy and embryology cranial nerves is necessary. We investigated nerve development, studied histological sections human embryos, quantitatively analyzed 3D reconstructions. A total 28 sectioned histologically stained embryos (Carnegie stage [CS] 10 to 23 [21-60 days development]) were completely digitalized by manual annotation using...
Women with a vulnerable health status, as determined by low socioeconomic status and poor lifestyle behaviours, are at risk for adverse pregnancy outcomes. Offering tailored preconception care can significantly help to improve We hypothesize that so-called 'nudges' be successful way of increasing the uptake care. A nudge is behavioural intervention supports healthy choices making them easier choose. Nudging, however, raises many moral questions. Effectiveness respect autonomy are, among...
Poor sleep quality during pregnancy is associated with both antepartum and postpartum depression adverse birth outcomes. This study evaluated objective subjective the effects on subsequent course of depressive symptoms in psychiatric patients. observational explorative was embedded an ongoing focusing pregnant women a mental disorder performed 18 patients (24–29 weeks pregnant). Depressive were assessed throughout using Edinburgh Postnatal Depression Scale (EPDS) 5-week intervals. Sleep...
Retinal hemosiderin deposition is a histologic indicator of sustained hemorrhage but cannot be used to precisely estimate the elapsed time since an episode trauma. A 5-month-old male infant was admitted hospital after acute deterioration. Examination revealed encephalopathy, subdural hematomas, and retinal hemorrhages consistent with abusive head trauma (AHT). At age 3, he readmitted spontaneous osteopenic fracture right femur. The patient deteriorated died unsuccessful resuscitation....
Background Women with a low socioeconomic status often have vulnerable health due to an accumulation of health-deteriorating factors such as poor lifestyle behaviors, including inadequate nutrition, mental stressors, and impaired literacy agency, which puts them at unnecessary high risk adverse pregnancy outcomes. Adequately preparing for through preconception care (PCC) uptake improvement can improve these We hypothesize that nudging is successful way encouraging engagement in PCC. A nudge...
Using prescription drugs during pregnancy is challenging and approached with caution. In this study, we present population-based information on patterns of benzodiazepines benzodiazepine-related in the peripartum period. A study 1,154,817 pregnancies between 1997 2015 Denmark, which 205,406 (17.8%) women a psychiatric history. Prescription starting Anatomical Therapeutic Chemical codes N05BA, N05CD, N05CF from 12 months before to following were identified. We used generalised estimating...
Background A low socioeconomic status is associated with a vulnerable health (VHS) through the accumulation of health-related risk factors, such as poor lifestyle behaviors (eg, inadequate nutrition, chronic stress, and impaired literacy). For pregnant women, VHS translates into high incidence adverse pregnancy outcomes therefore pregnancy-related inequity. We hypothesize that stimulating adequate preparation, targeting preconception care (PCC) uptake, can reduce these inequities improve...
To evaluate the current practice of preconception care in Netherlands and perceptions birth professionals concerning care.We have developed a digital questionnaire conducted cross-sectional study by distributing among 102 organisations: 90 primary midwifery practices obstetric departments 12 hospitals Southwest region between December 2020 March 2021. One professional per organization was asked to complete questionnaire. Descriptive statistics were used present results.Respondents...
<sec> <title>BACKGROUND</title> A low socioeconomic status is associated with a vulnerable health (VHS) through the accumulation of health-related risk factors, such as poor lifestyle behaviors (eg, inadequate nutrition, chronic stress, and impaired literacy). For pregnant women, VHS translates into high incidence adverse pregnancy outcomes therefore pregnancy-related inequity. We hypothesize that stimulating adequate preparation, targeting preconception care (PCC) uptake, can reduce these...
<sec> <title>UNSTRUCTURED</title> A Digital Twin (DT), which is defined originally as a virtual representation of physical asset, system or process, new concept in healthcare. DT healthcare cannot be single technology, but domain adapted multi-modal modelling approach, incorporates the acquisition, management, analysis, prediction, and interpretation data, aiming to improve medical decision making. However, there are many challenges barriers that has overcome before can used In this...