Saber Abdelkader Saïdi

ORCID: 0000-0003-3592-7968
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Research Areas
  • Pharmacology and Obesity Treatment
  • Curcumin's Biomedical Applications
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Reproductive biology and impacts on aquatic species
  • Diet and metabolism studies
  • Nuts composition and effects
  • Botanical Research and Applications
  • Organ Transplantation Techniques and Outcomes
  • Chemical synthesis and alkaloids
  • Livestock Management and Performance Improvement
  • Seaweed-derived Bioactive Compounds
  • Mercury impact and mitigation studies
  • Circadian rhythm and melatonin
  • Liver Disease Diagnosis and Treatment
  • Fatty Acid Research and Health
  • Cardiac Ischemia and Reperfusion
  • Algal biology and biofuel production
  • Metabolism and Genetic Disorders
  • Medicinal Plants and Neuroprotection
  • Anesthesia and Neurotoxicity Research
  • Agricultural Systems and Practices
  • Microbial Metabolites in Food Biotechnology
  • Drug-Induced Hepatotoxicity and Protection
  • Nigella sativa pharmacological applications

University of Jeddah
2017-2024

University of Sfax
2010-2018

KU Leuven
2017

Universitair Ziekenhuis Leuven
2013

A 45-day feeding trial was conducted to assess the capacity of juvenile Nile tilapia (2.12 ± 0.02 g) utilize different sources carbohydrate in their diets. Growth performance, nutrient digestibility, hematological parameters, and hepatic oxidative stress were evaluated. Four experimental diets formulated be isonitrogenous (25% crude protein) isolipidic (10% lipid), each containing 20% glucose (GLU-diet), maltose (MAL-diet), dextrin (DEX-diet), corn starch (CST-diet), respectively. At end...

10.3390/ani10101913 article EN cc-by Animals 2020-10-19

Introduction. Recently, plant natural food colorants have received a growing interest due to their therapeutic and preventive activities against various diseases. This study is aimed at evaluating the phytochemical composition by high-performance liquid chromatography with diode array detection (HPLC-DAD) antiulcer effect of red beetroot betalains (BRB). Materials Methods. Ethanol was used for gastric mucosa damage, ulcer, inflammation induction in rat. Results. HPLC-DAD data revealed...

10.1155/2023/9522830 article EN Journal of Food Processing and Preservation 2023-08-01

The study evaluated the phytochemical composition of Ephedra alata and its effects on α-amylase lipase enzymes diabetic-induced liver-kidney-testes toxicities to determine anti-diabetic, anti-obesity, anti-toxic potentials plant. Obesity was induced by a high-fat fructose diet (HFFD). Various compounds were identified quantified: cafeic acid, apigenin 7-O-glucoside, apigenin, rutin, luteolin p-Coumaric acid others in EA aqueous extract (EAWE). In vitro, this showed that EAWE strongly...

10.1016/j.heliyon.2022.e11954 article EN cc-by Heliyon 2022-11-29

The goal of this study is to investigate the antiulcer effects betalain-rich extract (BRE). Gastric ulcer was induced by administration ethanol gastric gavage route. This showed that supplementation BRE from pulp and peel at 800 mg/kg rats with ethanol-induced gastric-ulcer significantly reduced volume secretion (VGS) 35% ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>p</mi> <mo>=</mo> <mn>0.001</mn> </math> ) 34% id="M2"> <mn>0.0009</mn> ), index (UI) 41% id="M3"> 68%...

10.1155/2023/2215454 article EN cc-by Journal of Food Quality 2023-07-03

A 45-day feeding trial was conducted to study the effect of replacing dietary fish meal (FM) with a tuna by-product (TBM) on growth, feed efficiency, carcass composition and stress oxidative status juvenile Nile tilapia, Oreochromis niloticus L.). Triplicate groups (2.21 ± 0.01 g) were fed four iso-nitrogenous iso-energetic diets. The control diet (A0) used FM as sole source animal protein. In other three diets (A10–A30), 33%–100% substituted by TBM at 10% increments. There no significant...

10.1111/j.1365-2109.2010.02594.x article EN Aquaculture Research 2010-07-16

This study investigated the hypothesis that administration of tilapia fish oil diet would attenuate warm liver ischemia/reperfusion injury (IRI) and whether modulates prooxidant/antioxidant status. Male Wistar rats were subjected to 30 min approximately 70% hepatic ischemia followed by 1, 12, 24 h reperfusion. Rats randomly divided into three groups: sham-operated group (SO), control-warm (WI) group, Oil-WI given for 3 weeks IRI. Aspartate aminotransferase (AST) alanine (ALT) levels measured...

10.1177/0960327114531991 article EN Human & Experimental Toxicology 2014-06-16

This study aimed to investigate the potential effects of melatonin on aluminium-induced toxicity in a rat model using set biochemical, inflammatory, oxidant, lipid profile criteria and hepatic integrity (verified by hematoxylin-eosin staining). The results indicated that AlCl3 administration during 60 days (100 mg/kg b.w.) significantly increased activities transaminases AST ALT 46% (p < 0.001) 21% 0.01), lactate dehydrogenase (LDH) 30% 0.001), levels bilirubin 85% total cholesterol 115%...

10.4149/gpb_2015028 article EN PubMed 2015-10-01

Context: Intestinal ischemia-reperfusion (IIR) not only leads to severe intestine damage but also induced subsequent destruction of remote organs.Objective: We investigated the protective effect Pistascia lentiscus L. (Anacardiaceae) oil on IIR.Materials and methods: Wistar rats were divided into three groups: sham, intestinal IR P. pretreatment (n = 18 each). In group, was administered 1 h before induction warm ischemia.Results: IIR led liver manifested as a significant (p < .05) increase...

10.1080/13813455.2017.1302961 article EN Archives of Physiology and Biochemistry 2017-03-24

Nutritional fact study has prime importance to make the species edible and commercially viable food consumers. This is first report that indicates chemical characterization, functional, antioxidant antihypertensive properties of Cymodocea nodosa evaluate its nutritional status.Physico-chemical determination was determined by colorimetric spectroscopic analysis. The functional texture were evaluated since a desirable should be retained. Bioactive substances liquid chromatography-high...

10.1186/s12944-017-0626-z article EN cc-by Lipids in Health and Disease 2017-12-01

Hepatic ischemia/reperfusion injury (IRI) is a major cause of liver damage during surgery and transplantation. Plants have historically been used in treating damage, Hammada scoparia (Pomel) (Chenopodiaceae) has reported to possess broad spectrum pharmacological therapeutic activities.In this study, flavonoid-enriched fraction was before the warm ischemia (WI) process as preconditioning combination with technical postconditioning evaluate their protective effects.The rats were divided into...

10.3109/13880209.2015.1010737 article EN Pharmaceutical Biology 2015-04-17

Abstract The increasing demand for donor organs and the decreasing organ quality is prompting research toward new methods to reduce ischemia reperfusion injury (IRI). Several strategies have been proposed protect preserved from this injury. Before curcumin/dextrin complex (CDC), a potent antioxidant anti‐inflammatory agent, can be used clinically we need better understand intracellular uptake under hypothermic conditions on rat model of liver donation after circulatory death (DCD) brain...

10.1002/bdd.2108 article EN Biopharmaceutics & Drug Disposition 2017-10-03

The growth of the aquafeed sector is highly dependent upon availability fish feed with a balanced nutritional composition. use prebiotics and probiotics can be an effective solution to increase bioavailability components. In this study, we evaluated effect dietary supplementation β-propeller phytase (0, 600, 1200, 1800 2400 U/kg) from Bacillus mannan oligosaccharide (MOS) 2, 4 8 g/kg) on performance nutrient digestibility Nile tilapia over 45 days. findings showed that adding significantly...

10.3390/fishes8120574 article EN cc-by Fishes 2023-11-24

Mosquito-borne diseases caused by infected mosquitoes like dengue fever, Zika Chikungunya and malaria are spread to humans through biting causing disease epidemics all over the world. This indicates necessity for new mosquito-borne control strategies in Saudi Arabia internationally. study evaluated potential of local bacteria isolated from soil Rahat region Makkah, biocontrol Aedes aegypti larvae, a major agent transmission fever. Soil samples were collected region, Makkah isolation...

10.3844/ojbsci.2022.520.528 article EN OnLine Journal of Biological Sciences 2022-04-01
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