A5056070603- Thyroid Cancer Diagnosis and Treatment
- Nutritional Studies and Diet
- Cancer Risks and Factors
- Health Systems, Economic Evaluations, Quality of Life
- Radiation Dose and Imaging
- Meta-analysis and systematic reviews
- Nutrition, Health, and Society Studies
- Statistical Methods in Clinical Trials
- Patient-Provider Communication in Healthcare
- Lung Cancer Diagnosis and Treatment
- Risk Perception and Management
- Global Cancer Incidence and Screening
- Ethics in Clinical Research
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Systems and Practices
- Nutrition, Genetics, and Disease
- Virology and Viral Diseases
- Diet and metabolism studies
- Heavy Metal Exposure and Toxicity
- Electrical and Bioimpedance Tomography
- Dementia and Cognitive Impairment Research
- Viral Infections and Vectors
- Perfectionism, Procrastination, Anxiety Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Nutrition and Health Studies
University of Geneva
2020
University Hospital of Geneva
2018-2020
Hôpital Beau-Séjour
2018
Institut Gustave Roussy
2006-2014
Inserm
2004-2014
Centre de recherche en Epidémiologie et Santé des Populations
2010-2014
Institut de Veille Sanitaire
2012
Université Paris-Sud
2010-2011
Laboratoire d'études sur les monothéismes
2007-2010
Université Paris-Saclay
2007-2010
The immunity conferred by SARS-CoV-2 vaccines and infections reduces the transmission of virus. To answer how effect is shared between a reduction infectiousness an increased protection against infection, we examined >50,000 positive cases >110,000 contacts from Geneva, Switzerland (June 2020 to March 2022). We assessed association secondary attack rate (i.e. proportion new among contacts) natural infection and/or vaccination, stratifying per four variants adjusting for index contacts'...
To study management of hypertension in the elderly a large population-based and to evaluate prevalence factors related awareness, treatment, control.The Three City study, among 9693 non-institutionalized individuals aged 65 years over.Blood pressure was measured with an automated electronic device, treatment assessed, during home interview. Hypertension defined by mean blood two measurements superior or equal 160/95 mmHg and/or intake antihypertensive medications.In final working sample 9090...
French Polynesia has one of the world's highest incidence rates thyroid cancer. A case-control study among native residents included 201 women diagnosed with differentiated cancer before age 56 years, between 1981 and 2004, matched to 324 population controls on date birth. Face-to-face interviews were conducted from 2002 2004. Odds ratios calculated by using conditional logistic regression reported in total group ethnic ("Polynesian" vs. "mixed"). The risk increased natural (odds ratio =...
Background: New Caledonia and French Polynesia have among of the world highest thyroid cancer incidence rates. Studies demonstrated a relationship between anthropometric parameters prevalence cancer. In this study we evaluated further body mass index (BMI) other on in populations. Methods: We performed pooled analysis two case–control studies Polynesia. included total 554 cases (65 men 489 women) differentiated cancers 776 population control subjects matched sex, age, study. Anthropometric...
Congenital Zika virus syndrome consists of a large spectrum neurologic abnormalities seen in infants infected with utero. However, little is known about the effects intrauterine infection on neurocognitive development children born without birth defects. Using case-control study design, we investigated temporal association cluster congenital defects infection. In nested study, also assessed early childhood recruited initial as controls who were defects,. We found evidence for an both...
Between 1966 and 1974, France conducted 41 atmospheric nuclear tests in Polynesia, but their potential health effects have not previously been investigated. In a case–control study, we compared the radiation exposure of almost all French Polynesians diagnosed with differentiated thyroid carcinoma between 1981 2003 (n=229) to 373 Polynesian control individuals without cancer from general population. Radiation exposures were estimated using measurements after tests, age at time each test,...
Background: To investigate differentiated thyroid cancer risk factors in natives of French Polynesia is interest because the very high incidence this archipelago. Materials and Methods: assess role various potential we performed a case-control study. The study included almost all Polynesians diagnosed with carcinoma between 1981 2003 (n=229) 373 Polynesian control individuals from general population without cancer. Results: Thyroid radiation dose received nuclear fallout before age 15,...
Background: Differentiated thyroid carcinoma is considered to be the nonhereditary cancer for which familial inheritance highest. To date, no aggregation analysis of this has been performed in Maohi populations, exhibit a very high incidence rate. Therefore, we evaluate risk differentiated associated with family history natives French Polynesia. Methods: We investigated first-degree relatives 225 cases carcinomas diagnosed between 1979 and 2004 patients born Polynesia, 368 randomly selected...
Forty-one atmospheric nuclear weapons tests (plus five safety tests) were conducted in French Polynesia between 1966 and 1974. To evaluate the potential role of testing on a high incidence thyroid cancer observed since 1985 Polynesia, population-based case-control study was performed. The included 602 subjects, either cases or controls, all aged less than 40 y at end Radiation doses to thyroids subjects assessed based available historical results radiation measurements. These mainly found...
Background: Numerous studies have suggested that selenium deficiency may be associated with an increased risk for several types of cancer, but few focused on thyroid cancer. Materials and Methods: We examined the association between post-diagnostic fingernail levels differentiated cancer in a French Polynesian matched case-control study. Conditional logistic regression models were used to estimate odds ratios 95% confidence intervals. Results: The median concentration among controls was...
Abstract Background Clinical trials are essential to improve knowledge of anesthesia and perioperative medicine. Unfortunately, many studies face participant-recruitment issues fail include the planned number participants. There is limited published data about how information delivered study or experiences attitudes prospective participants influence willingness participate. The purpose this was identify such factors in domain care. Methods We performed a cross-sectional at Geneva University...
The objective of the study is to estimate proportion statistically significant survival improvements reported in randomized trials cancer treatments that are also compatible with a clinically negligible benefit.This cross-sectional reports clinical increase overall survival, published leading journals between 2009 and 2019. main outcome variable was hazard ratio (HR) for its upper 95% confidence limit. An HR 0.95 implies an absolute gain ≤1.9%, 0.90 ≤3.8%; we reasoned such gains can be...
P-160 Abstract: In order to study the potential consequences of Chernobyl nuclear power plant accident in April 1986 and specify risk factors differentiated thyroid cancer for children young adults, we are carrying out, close collaboration with registries, a population-based case-control East regions France, that were most contaminated by fallout from accident. The will include total more than 700 cases controls. case patients must have been born January 1, 1971 diagnosed histologically...