A5077588565- Textile materials and evaluations
- COVID-19 Clinical Research Studies
- Advanced Sensor and Energy Harvesting Materials
- Climate Change and Health Impacts
- Advancements in Transdermal Drug Delivery
- SARS-CoV-2 and COVID-19 Research
- Architecture and Computational Design
- SARS-CoV-2 detection and testing
- Virus-based gene therapy research
- Skin Protection and Aging
- Optical Imaging and Spectroscopy Techniques
- Interactive and Immersive Displays
- Mycobacterium research and diagnosis
- Ocular Surface and Contact Lens
- Phagocytosis and Immune Regulation
- Animal Virus Infections Studies
- Tactile and Sensory Interactions
- Infectious Diseases and Mycology
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
Jagiellonian University
2020-2024
ETH Zurich
2016-2017
Swiss Federal Laboratories for Materials Science and Technology
2015-2017
The skin properties, structure, and performance can be influenced by many internal external factors, such as age, gender, lifestyle, diseases, a hydration level that vary in relation to the environment. aim of this work was demonstrate multifaceted influence water on human through combination vivo confocal Raman spectroscopy images volar–forearm captured with laser scanning microscopy. By means pilot study, authors have both qualitatively quantitatively studied changing depth-dependent...
The properties of human skin strongly depend on hydration. Skin friction, elasticity and roughness change significantly in the presence water. This paper presents a new bio-mimicking gelatine-based physical model that simulates frictional behaviour against widely-used standard textile under dry wet conditions over broad range applied normal load (0.5–5 N) amount water at interface (0–100 μl/cm2). proposed shows good agreement with both conditions. In addition, tensile Young's modulus surface...
Abstract SARS-CoV-2 genome annotation revealed the presence of 10 open reading frames (ORFs), which last one (ORF10) is positioned downstream N gene. It a hypothetical gene, was speculated to encode 38 aa protein. This protein does not share sequence similarity with any other known and cannot be associated function. While role this ORF10 proposed, there growing evidence showing that coding region. Here, we identified variants in gene prematurely terminated. The disease attenuated,...
Abstract Clinical data indicate that COVID-19 causes cardiovascular complications, regardless of the severity disease. In this work, we have shown SARS-CoV-2 infection vascular dysfunction due to modification endothelial cell elasticity. We used human pulmonary cells (HPAECs) expressing ACE2 receptor as a model endothelium. This system mimics in vivo conditions, it allows virus entry but not replication. As reference, A549 epithelial cells, well-described supports productive replication...
Mycobacterial diseases of humans and animals can be caused by mycobacteria other than tuberculosis (MOTT). The transmission the infection primarily occurs via respiratory or oral routes, but also a damaged skin barrier. MOTT have high resistance to external factors; therefore, infected, undiagnosed pose risk for public health.The case study describes mycobacterial in domestic cat. correct diagnosis was reached four months after appearance first clinical signs. Those were purulent,...
Development of artificial or robotic skin implementing optical touch sensors is considered. Integration polymeric fibers in elastomeric nanocomposite matrix biomimicking human specification as flexibility and large-area sensing presented. The principle directly linked to deformation the fiber itself under applied weight solicitations.
<title>Abstract</title> Clinical data indicate that COVID-19 causes cardiovascular complications, regardless of the severity disease. In this work, we have shown SARS-CoV-2 infection vascular dysfunction due to modification endothelial cell elasticity. We used human pulmonary cells (HPAECs) expressing ACE2 receptor as a model endothelium. This system mimics in vivo conditions, it allows virus entry but not replication. As reference, A549 epithelial cells, well-described supports productive...
S ummary The COVID-19 pandemic caused by SARS-CoV-2 has been socially and economically devastating. Despite an unprecedented research effort, effective therapeutics are still missing to limit severe disease mortality. Using high-throughput screening, we identified acriflavine as a potent papain-like protease (PL pro ) inhibitor. NMR titrations co-crystal structure confirm that blocks the PL catalytic pocket in unexpected binding mode. We show drug inhibits viral replication at nanomolar...