A5012350024- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Pelvic floor disorders treatments
- Minimally Invasive Surgical Techniques
- Gynecological conditions and treatments
- Anorectal Disease Treatments and Outcomes
- Genetic factors in colorectal cancer
- Sarcoma Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Urologic and reproductive health conditions
- Bladder and Urothelial Cancer Treatments
- Pregnancy and preeclampsia studies
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Urinary and Genital Oncology Studies
- Colorectal Cancer Surgical Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Perinatal Health Interventions
- Reproductive System and Pregnancy
- Gestational Diabetes Research and Management
- Surgical Simulation and Training
- Radiomics and Machine Learning in Medical Imaging
- Intraperitoneal and Appendiceal Malignancies
Policlinico Tor Vergata
2015-2023
University of Rome Tor Vergata
2013-2022
Cluster in Biomedicine
2013
Università Cattolica del Sacro Cuore
2004
Altered circulating cell-free DNA (cfDNA) levels are related to cancer development and aggressiveness. Up now, very few studies have been performed for evaluating cfDNA content in endometrial (EC).First, we measured release blood serum of EC patients collected before surgery the beginning any treatment by SYBR Gold assay correlated it with tumor We also assessed relative mitochondrial (cfmtDNA) qRT-PCR. Next, BMI, age, hypertension inflammation markers.CfDNA higher G2 G3 compared G1 sera. A...
Circulating cell-free DNA (cfDNA) and its integrity index may represent a rapid noninvasive "liquid biopsy" biomarker, which gives important complementary information for diagnosis, prognosis, treatment stratification in cancer patients. The aim of our study was to evaluate the possible role cfDNA as tool endometrial (EC) management. Alu-quantitative real-time PCR (qPCR) analysis wasprformed on 60 serum samples from preoperative EC patients randomly recruited. Both content were measured by...
The purpose of this study was to evaluate the feasibility and morbidity total laparoscopic debulking surgery in treatment advanced ovarian cancer after neoadjuvant chemotherapy.We performed a retrospective review approach patients with histologically confirmed epithelial (International Federation GynaecologyObstetrics stages IIIC-IV) who received 3 courses chemotherapy, from January 2010 December 2014, at Gynaecologic Oncologic Unit, "Regina Elena" National Cancer Institute, Rome, Italy.A 30...
Objective: The aim of our study was to investigate the role excised vaginal cuff length as a prognostic factor in terms DFS and recurrence rate/site, low-risk endometrial cancer (EC) patients. Moreover, we correlated with expression L1CAM. Material Methods: From March 2001 November 2016, retrospective data collection conducted women undergoing surgical treatment for EC according ESMO-ESGO-ESTRO consensus guidelines. Patients were divided into three groups their length: V0 without cuff, V1...
The primary aim is to evaluate the surgical and oncological outcome of robotic radical hysterectomy (RRH) plus pelvic lymphadenectomy in locally advanced cervical cancer (LACC) after neoadjuvant chemotherapy (NACT). secondary compare results RRH NACT with a historical cohort patients undergoing laparoscopic or abdominal for LACC NACT.We enrolled total 41 this study RRH, who achieved clinical partial complete response NACT. outcomes 2 groups were compared: group (41 patients) laparotomic (43...
The present study investigated the association between genetic polymorphisms of selected thrombophilic factors with recurrent miscarriage (RM). for plasminogen activator inhibitor-1 4G/5G (PAI-1), Factor V Leiden (FVL), II G20210A (FII) and methylenetetrahydrofolate reductase MTHFR C677T were determined in 186 RM women 129 healthy women. In women, frequency heterozygosity PAI-1 5G/4G (31%) was significantly higher than controls (5G/4G: 22%) whereas no difference found case homozygosity 4G/4G...
Abstract Aim The aim of this study was to investigate the gestational age (GA) pregnancy loss in women with unexplained recurrent miscarriage (RM) and determine whether miscarriages occur at similar GA RM women. Material Methods This retrospective carried out a university hospital included 288 RM. which each occurred carefully determined. Overall, 739 were analyzed. Results had median 7 weeks (range: 3–20). In women, 47.2% ( n = 136) experienced within 1‐week range 53.4% 154) same period...
UTROSCTs ( Uterine Tumors Resembling Ovarian Sex Cord Tumors) are rare neoplasms of unknown etiology usually occurring in middle-aged women. Less than 100 cases UTROSCT have been reported so far. Although the typical behavior is benign, metastatic and recurrent can occur. Here we describe an extremely case vaginal vault recurrence 5 years after total hysterectomy with bilateral salpingo-oophorectomy. Though rare, should always be taken into account differential diagnosis uterine masses...
A case of high-grade endometrial stromal sarcoma, confined into an intrauterine polypoid growth, in a woman with history breast cancer who was treated adjuvant tamoxifen. Based on the findings, sarcoma diagnosed. The patient underwent total hysterectomy and bilateral salpingo-oophorectomy multiple omental biopsies. Pathological examination uterine sections showed absence residual tumor cells uterus. endometrium patterns glandular cystic hyperplasia. After 14 months follow-up, is well free...
The objective was to assess the feasibility, operative and postoperative outcome, complications in use of minilaparotomy for type II III radical hysterectomy (RH) pelvic lymphadenectomy (PLN) early-stage cervical/endometrial cancer. A pilot study on 91 consecutive patients submitted RH PLN cancer performed between March 2002 May 2003 Division Gynecologic Oncology (UCSC, Rome). Thirty-two cases (35.2%) were eligible minilaparotomy. mean time 156.7 min, whereas intraoperative estimate blood...
•Superficial myofibroblastoma of the Labia Majora.•Differential diagnosis between vulvar superficial and cyst/hydrocele Nuck duct.•Differential inguinal/crural hernia.
Background: The efficacy and safety of a cervical ripening balloon (CRB) in women with previous cesarean section (CS) unfavorable Bishop score are still controversial. Methods: A retrospective cohort study was performed across six tertiary hospitals from 2015 to 2019. Women one transverse CS, singleton cephalic term pregnancy BS < 6 were included if submitted labor induction CRB. main outcome the rate vaginal birth after (VBAC) CRB ripening. Secondary outcomes abnormal composite fetal...
Cesarean presents increased risk of adverse outcomes, such as endometritis, bacteremia, peritonitis, and maternal fever. This retrospective study aims to evaluate, for the first time in Literature, effects Betadine washing versus normal saline after uterine closure women undergoing cesarean delivery (CD) at ≥36 gestational weeks.Of 2080 patients identified retrospectively analysis Department Obstetrics Gynecology San Camillo Hospital Rome, 1042 were assigned "Betadine group" 1038 "No group"....