A5012410418- Proteoglycans and glycosaminoglycans research
- Glycosylation and Glycoproteins Research
- Protease and Inhibitor Mechanisms
- Cell Adhesion Molecules Research
- Fibroblast Growth Factor Research
- Carbohydrate Chemistry and Synthesis
- Peptidase Inhibition and Analysis
- HER2/EGFR in Cancer Research
- Cancer Cells and Metastasis
- Bone health and treatments
- Connective tissue disorders research
- Polysaccharides and Plant Cell Walls
- Microfluidic and Capillary Electrophoresis Applications
- Glaucoma and retinal disorders
- Estrogen and related hormone effects
- Polysaccharides Composition and Applications
- Monoclonal and Polyclonal Antibodies Research
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Bacterial biofilms and quorum sensing
- MicroRNA in disease regulation
- TGF-β signaling in diseases
- Analytical Chemistry and Chromatography
- Cancer, Hypoxia, and Metabolism
- Extracellular vesicles in disease
University of Patras
2016-2025
FORTH Institute of Chemical Engineering Sciences
2014-2025
Foundation for Research and Technology Hellas
2014-2025
St Andrew's Healthcare
2021-2024
Heidelberg (Poland)
2023-2024
International School of Trieste
2023-2024
FC Barcelona
2023-2024
Hudson Institute
2021-2024
National Institute on Consumer Education
2016-2020
University of Crete
2006-2013
The 17β-estradiol (E2)/estrogen receptor alpha (ERα) signaling pathway is one of the most important pathways in hormone-dependent breast cancer. E2 plays pivotal roles cancer cell growth, survival, and architecture as well gene expression regulatory mechanisms. In this study, we established stably transfected MCF-7 cells by knocking down ERα (designated MCF-7/SP10 + cells), using specific shRNA lentiviral particles, compared them with control (MCF-7/c). Interestingly, silencing strongly...
Hyaluronan (HA) modulates key cancer cell functions through interaction with its CD44 and receptor for hyaluronic acid-mediated motility (RHAMM) receptors. HA was recently found to regulate the migration of fibrosarcoma cells in a manner specifically dependent on size. Here, we investigated effect HA/RHAMM signaling ability HT1080 adhere onto fibronectin. Low molecular weight (LMWHA) significantly increased (p ≤ 0.01) adhesion capacity cells, which high inhibited. The RHAMM-deficient but not...