A5072175971- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- Systemic Sclerosis and Related Diseases
- Pain Mechanisms and Treatments
- Salivary Gland Disorders and Functions
- Eosinophilic Esophagitis
- Spondyloarthritis Studies and Treatments
- Gastroesophageal reflux and treatments
- Peripheral Neuropathies and Disorders
- Inflammatory Myopathies and Dermatomyositis
- Diabetes and associated disorders
- Otitis Media and Relapsing Polychondritis
- Ocular Diseases and Behçet’s Syndrome
- Vasculitis and related conditions
- Lymphatic System and Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- IL-33, ST2, and ILC Pathways
- Genital Health and Disease
- Myofascial pain diagnosis and treatment
- Eosinophilic Disorders and Syndromes
- IgG4-Related and Inflammatory Diseases
- Liver Diseases and Immunity
- Retinal and Optic Conditions
- Enhanced Recovery After Surgery
Center for Rheumatology
2021-2024
ORCID
2024
Ankara University
2018-2023
Sağlık Bilimleri Üniversitesi
2021
Background/Objective Interleukin (IL) 35 is a member of the IL-12 family. Studies show that IL-35 an important anti-inflammatory cytokine and suppresses effector T-cell activity. In this study, we aimed to evaluate serum levels in systemic sclerosis (SSc) patients its potential relation with clinical findings. Methods We conducted cross-sectional analysis 70 SSc 29 healthy volunteers single center 5 months' period. Extension skin fibrosis was evaluated by using modified Rodnan score. Disease...
Aim of the work: To evaluate value three hematological indices to determine subclinical inflammation in Familial Mediterranean Fever (FMF) patients during attack-free period. Patients and methods: This study included 60 FMF without FMF-related symptoms or signs preceding month 50 age sex matched healthy control. Subclinical was defined as presence elevated C-reactive protein (CRP) > 5 mg/dL and/or serum amyloid A (SAA) levels 6.4 mg/L absence any related clinical symptoms. The...
The aims of this study were to compare the frequency Helicobacter pylori between patients with rheumatoid arthritis (RA) and without methotrexate (MTX)-related gastrointestinal system (GIS) intolerance, demonstrate associated factors such intolerance.The data 9756 RA who presented January 2011 December 2020 evaluated. Methotrexate-related GIS intolerance was defined as discontinuation MTX owing dyspeptic symptoms despite supportive measures detected in 1742 (31.3%) among 5572 users. A total...
Calprotectin is an inflammatory biomarker which assesses disease activity in rheumatoid arthritis (RA). The objective of this study was to test whether serum calprotectin associated with clinical and ultrasonographic patients RA, analyse its predicting value for evaluation despite normal C-Reactive protein (CRP) levels.We included 80 RA 30 healthy subjects. Patients were examined clinically by ultrasound, (US7 score) along laboratory parameters (calprotectin, CRP, erythrocyte sedimentation...
The aim of this study was to determine the association rheumatoid arthritis-related lung disease (RA-LD) and its subtypes with all-cause mortality.
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare autoimmune disease usually involving small vessels and progressing with necrotizing inflammation. Treatment requires long-term use of immunosuppressive agents to inhibit activity. Serious infections (SIs) are common complication in AAV.The aim this study was identify the risk factors for serious which required hospitalization patients AAV.In retrospective cohort study., we included 84 admitted Ankara University...
Background/aim: High mobility group box- 1 (HMGB- 1) is a nuclear protein acting as proinflammatory molecule. The serum HMGB- levels were found elevated in chronic inflammatory diseases. In this cross-sectional study, Behcet's disease (BD) patients and healthy controls (HC) studied. Also, its association with activity scores clinical findings evaluated. Materials methods: Ninety BD 50 age-sex matched HC included the study. Disease assessed by Behcet Current Activity Form (BDCAF) Syndrome...
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by microangiopathy, inflammation, fibrosis. Interstitial lung (ILD) common among SSc patients.This study aims to define the clinical, laboratory, and serologic characteristics of patients with ILD present frequency chest computed tomography features.Two hundred twenty-six who applied Rheumatology Department between January 2007 August 2019 were retrospectively examined. A total 100 (44.2%) determined. Clinical,...
Abstract Background Beta-2 microglobulin (β2M) is mainly released from activated lymphocytes. Increased serum β2M levels have been shown in autoimmune diseases. The aim of this study was to analyse the rheumatoid arthritis (RA) patients and evaluate its relationship with disease activity measures. Material Methods This cross-sectional included 137 RA patients, 102 ankylosing spondylitis (AS) 50 healthy controls (HC). To assess 28-joint Disease Activity Score-Erythrocyte Sedimentation Rate...
The aim of this study was to identify predictive factors associated with pain catastrophizing in women systemic lupus erythematosus (SLE).A total 104 volunteered a diagnosis participated the study. Pain Catastrophizing Scale, Body Awareness Questionnaire, Tampa Scale Kinesiophobia, and Beck Depression Inventory were used assess patients. Correlations between (dependent variable) independent variables (age, body mass index, disease activity, organ damage, depression, kinesiophobia, awareness)...
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ÖzAmaç: Behçet hastalığı deri, mukoza, eklem ve göz başta olmak üzere birçok sistemi tutabilen, nedeni bilinmeyen bir vaskülittir.Bu çalışmada hastalarında koronavirüs hastalığı-2019 (COVID-19) aşılama durumu incelendi.Behçet hastalarına ait özelliklerin, COVID-19 ile ilgili verilerle olan ilişkisi sorgulandı
IntroductionAxial spondyloarthritis (axSpA) is a chronic inflammatory condition which mainly affects the spine and sacroiliac joints.AxSpA divided into 2 different types according to X-ray imaging of joints, radiographic axSpA (r-axSpA) non-radiographic (nr-axSpA). [1]Patients with may also experience dactylitis, enthesitis, peripheral arthritis.Furthermore, extra-articular findings
<h3>Background:</h3> Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with wide spectrum of clinical manifestations such as organ damage, pain, fatigue, sleep disorders, depression and cognitive deficits. It known that pain catastrophising may have serious impact in individuals SLE. Furthermore, maladaptive coping strategies are linked to higher levels functional impairment <h3>Objectives:</h3> The aim this study was identify factors associated detect possible susceptible...
Amaç: Retroperitoneal fibrozis nadir görülen fibroenflamatuvar
Amaç: Çalışmamızda romatoid artrit (RA) nedeni ile tofasitinib kullanan hastaların klinik, laboratuvar ve demografik özelliklerini belirlemek ilaçta kalım oranlarını saptamak amaçlanmıştır
Amaç: Romatoid artrit (RA), enflamatuvar
Objectives: Interleukin-33 (IL-33) is a novel cytokine which belongs to IL-1 superfamily.It shares structural homology and common signaling pathway with IL-1β whose excessive secretion results in Familial Mediterranean Fever (FMF).In this study, we aimed evaluate the serum IL-33 its decoy receptor sST2 levels patients FMF correlation disease activity. Materials Methods:In cross-sectional single-centered 76 30 age-and sex-matched healthy individuals were recruited.Disease activity was...
ÖZET Mart 2020'de pandemi olarak ilan edilen yeni tip koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)], esas solunum sistemi belirti ve bulguları ile seyretmektedir.Şiddetli akut sendromu-koronavirüs-2 virüsünün giriş reseptörü olan anjiyotensin dönüştürücü enzim 2 reseptörlerinin, vücutta yaygın doku dağılımı mevcuttur.Bu nedenle hastalıkta bulgularının yanı sıra diğer sistemlerle ilgili semptom bulgular da izlenebilmektedir.Literatürde, COVID-19 birlikte görüldüğü en sık...
Amaç: Psöriatik artrit (PsA