- Diabetes Management and Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes and associated disorders
- Diabetic Foot Ulcer Assessment and Management
- Diabetes Treatment and Management
- Diet and metabolism studies
- Wound Healing and Treatments
- Metabolism, Diabetes, and Cancer
- Pressure Ulcer Prevention and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic function and diabetes
- Hormonal and reproductive studies
- Bariatric Surgery and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Cardiovascular Function and Risk Factors
- Clinical practice guidelines implementation
- Pituitary Gland Disorders and Treatments
- Pharmacology and Obesity Treatment
- Streptococcal Infections and Treatments
- Adrenal Hormones and Disorders
- Nutrition and Health in Aging
- Sepsis Diagnosis and Treatment
- Muscle metabolism and nutrition
Norfolk and Norwich University Hospitals NHS Foundation Trust
2016-2025
University of East Anglia
2016-2025
Norfolk and Norwich University Hospital
2015-2024
Norwich Research Park
2005-2024
Action for Boston Community Development
2024
National Health Service
2009-2023
West Suffolk NHS Foundation Trust
2016
Florida College
2016
University of Florida
2016
Vanderbilt University Medical Center
2016
Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, compared with potential harm, unknown.We performed a 2-year, placebo-controlled, randomized, double-blind study involving 87 elderly men low levels of sulfated form DHEA bioavailable 57 women DHEA. Among men, 29 received DHEA, 27 testosterone, 31 placebo. women, 30 Outcome measures included physical performance, body composition, bone mineral density (BMD), glucose...
Diabet. Med. 28, 508–515 (2011) Abstract The Joint British Diabetes Societies guidelines for the management of diabetic ketoacidosis (these do not cover Hyperosmolar Hyperglycaemic Syndrome) are available in full at: http://www.diabetes.org.uk/About_us/Our_Views/Care_recommendations/The‐Management‐of‐Diabetic‐Ketoacidosis‐in‐Adults ; http://www.diabetes.nhs.uk/publications_and_resources/reports_and_guidance http://www.diabetologists‐abcd.org.uk/JBDS_DKA_Management.pdf . This article...
Diabet. Med. 29, 420–433 (2012) Abstract These Joint British Diabetes Societies guidelines, commissioned by NHS Diabetes, for the perioperative management of adult patient undergoing surgery are available in full Supporting Information. This document goes through seven stages journey when having surgery. are: primary care referral; surgical outpatients; preoperative assessment; hospital admission; surgery; post‐operative care; discharge. Each stage is given its own considerations, outlining...
Animal studies suggest that perfluorocarbons (PFCs) may alter sexual maturation. Relationships of human PFC exposure with puberty are not clear. We conducted a cross-sectional study to investigate whether perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) were associated indicators maturation in 2005–2006 survey residents PFOA water contamination from the Mid-Ohio Valley. Participants 3076 boys 2931 girls aged 8–18 years. They classified as having reached based on either...
This article summarises the Joint British Diabetes Societies for Inpatient Care guidelines on management of ketoacidosis; available at https://abcd.care/resource/management-diabetic-ketoacidosis-dka-adults. The document explicitly states that when a person aged 16-18 is under care paediatric team, then guideline should be used, and if they are cared by an adult this used. takes into account new evidence use previous version document, particularly high prevalence hypoglycaemia hypokalaemia,...
The American Diabetes Association (ADA), European for the Study of (EASD), Joint British Societies Inpatient Care (JBDS), Clinical Endocrinology (AACE) and Technology Society (DTS) convened a panel internists diabetologists to update ADA consensus statement on hyperglycaemic crises in adults with diabetes, published 2001 last updated 2009. objective this report is provide up-to-date knowledge about epidemiology, pathophysiology, clinical presentation, recommendations diagnosis, treatment...
Summary Introduction Glucagon‐like peptide‐1 receptor agonists, dual glucose‐dependent insulinotropic peptide agonists and sodium‐glucose cotransporter‐2 inhibitors are used increasingly in patients receiving peri‐operative care. These drugs may be associated with risks of pulmonary aspiration or euglycaemic ketoacidosis. We produced a consensus statement for the management adults taking these drugs. Methods This multidisciplinary included surgeons, anaesthetists, physicians, pharmacists...
OBJECTIVE To assess the effect of dietary flavonoids on cardiovascular disease (CVD) risk in postmenopausal women with type 2 diabetes established statin and hypoglycemic therapy. RESEARCH DESIGN AND METHODS Despite being medicated, patients have elevated CVD risk, particularly women. Although been shown to reduce factors healthy participants, no long-term trials examined additional benefits medicated diabetes. We conducted a parallel-design, placebo-controlled trial diabetic randomized...
Glucocorticoids (steroids) are widely used across many medical specialities for their anti-inflammatory and immunosuppressive properties. However, one of major side effects is the development hyperglycaemia. It well recognized that high glucose levels in people with diabetes hospital associated harm increased lengths stay. The use glucocorticoid (steroid) treatment pre-existing will undoubtedly result worsening control, this may be termed 'steroid-induced hyperglycaemia', warrant temporary...
To examine, in a national survey, the outcomes of adult patients presenting with DKA 2014, mapped against accepted UK guidance.Data were collected standardized form covering clinical and biochemical outcomes, risk discharge planning. The was sent to all diabetes specialist teams (n = 220). Anonymized data on five consecutive admitted between 1 May 2014 30 November 2014.A total 283 forms received 281 patients) from 72 hospitals, which 71.4% used guidelines. results showed that 7.8% cases...
Significance We report a disease-causing mutation in the β-cell–enriched MAFA transcription factor. Strikingly, missense p.Ser64Phe was associated with either of two distinct phenotypes, multiple insulin-producing neuroendocrine tumors pancreas—a condition known as insulinomatosis—or diabetes mellitus, recapitulating physiological properties both an oncogene and key islet β-cell The implication these human phenotypes will provide insights into how this factor regulates activity well...