A5082628678- Per- and polyfluoroalkyl substances research
- Air Quality and Health Impacts
- Birth, Development, and Health
- Toxic Organic Pollutants Impact
- Occupational and environmental lung diseases
- Arsenic contamination and mitigation
- Vitamin D Research Studies
- Health, Environment, Cognitive Aging
- Infection Control and Ventilation
- Climate Change and Health Impacts
- Epigenetics and DNA Methylation
- Heavy Metal Exposure and Toxicity
- Carcinogens and Genotoxicity Assessment
- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- Environmental Justice and Health Disparities
- Bladder and Urothelial Cancer Treatments
- Chemical Analysis and Environmental Impact
- Heavy metals in environment
- Effects and risks of endocrine disrupting chemicals
- Environmental Impact and Sustainability
- Noise Effects and Management
- Water Quality and Pollution Assessment
- Occupational exposure and asthma
- Nutritional Studies and Diet
London School of Hygiene & Tropical Medicine
2016-2025
UK Health Security Agency
2022-2024
Royal Society of Tropical Medicine and Hygiene
2021-2024
Faculty of Public Health
2021-2023
Centre international de recherche sur le cancer
2005-2023
Karolinska Institutet
2004-2023
National Health Service
2023
University of London
2011-2022
Public Health England
2015-2022
International Society of Nephrology
2021
Background Municipal drinking water contaminated with perfluorinated alkyl acids had been distributed to one-third of households in Ronneby, Sweden. The source was firefighting foam used a nearby airfield since the mid-1980s. Clean provided from 16 December 2013. Objective To determine rates decline serum perfluorohexane sulfonate (PFHxS), perfluorooctane (PFOS) and perfluorooctanoate (PFOA), their corresponding half-lives. Methods Up seven blood samples were collected between June 2014...
The C8 Health Project was created, authorized, and funded as part of the settlement agreement reached in case Jack W. Leach, et al. v. E.I. du Pont de Nemours & Company (no. 01-C-608 W.Va., Wood County Circuit Court, filed 10 April 2002). stemmed from perfluorooctanoic acid (PFOA, or C8) contamination drinking water six districts two states near DuPont Washington Works facility Parkersburg, West Virginia.This study reports on methods results Project, a population created to gather data that...
Background: Perfluorooctanoic acid (PFOA) has been linked to cancer in occupational mortality studies and animal toxicologic research.Objective: We investigated the relationship between PFOA exposure among residents living near DuPont Teflon-manufacturing plant Parkersburg, West Virginia (WV).Methods: Our analyses included incident cases of 18 cancers diagnosed from 1996 through 2005 five Ohio (OH) counties eight WV counties. For each outcome, controls comprised all other study data set...
<h3>Background</h3> Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) are man-made compounds with widespread presence in human sera. In previous occupational adult studies, PFOA PFOS were positively associated serum lipid levels. <h3>Objective</h3> To interrogate associations between lipids children adolescents. <h3>Design</h3> Cross-sectional community-based study. <h3>Setting</h3> Mid–Ohio River Valley. <h3>Participants</h3> A total of 12 476 adolescents included the C8...
Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) persist in the environment are found relatively high concentrations animal livers. Studies humans have reported inconsistent associations between PFOA liver enzymes.We examined cross-sectional association serum PFOS with markers of function adults.The C8 Health Project collected data on 69,030 persons; these, a total 47,092 adults were included present analysis. Linear regression models fitted for natural log (ln)-transformed...
BACKGROUND: Firefighting foam-contaminated ground water, which contains high levels of perfluoroalkyl substances (PFAS), is frequently found around airports.In 2018 it was detected that employees at a municipal airport in northern Sweden had been exposed to short-chain PFAS along with legacy (i.e., PFOA, PFHxS, and PFOS) through drinking water.OBJECTIVES: In this study, we aimed describe the profile water biological samples (paired serum urine) estimate half-lives together PFAS.METHODS:...
Animal studies suggest that perfluorocarbons (PFCs) may alter sexual maturation. Relationships of human PFC exposure with puberty are not clear. We conducted a cross-sectional study to investigate whether perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) were associated indicators maturation in 2005–2006 survey residents PFOA water contamination from the Mid-Ohio Valley. Participants 3076 boys 2931 girls aged 8–18 years. They classified as having reached based on either...
Animal studies suggest that some perfluoroalkyl acids (PFAAs), including perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA) may impair thyroid function. Epidemiological findings, mostly related to adults, are inconsistent.We investigated whether concentrations of PFAAs were associated with function among 10,725 children (1-17 years age) living near a Teflon manufacturing facility in the Mid-Ohio Valley (USA).Serum levels thyroid-stimulating hormone...
Context:Obesity and diabetes are epidemic in the European Union (EU). Exposure to endocrine-disrupting chemicals (EDCs) is increasingly recognized as a contributor, independent of diet physical activity.
In this discussion paper, the transition from long-chain poly- and perfluorinated alkyl substances (PFASs) to fluorinated alternatives is addressed. Long-chain PFASs include perfluoroalkyl carboxylic acids (PFCAs) with 7 or more carbons, sulfonic (PFSAs) 6 their precursors. Because have been found be persistent, bioaccumulative toxic, they are being replaced by a wide range of alternatives. We summarize key concerns about potential impacts on human health environment in order provide concise...
Per- and polyfluoroalkyl substances (PFAS) are persistent with surfactant repellent properties. Municipal drinking water contaminated PFAS had been distributed for decades to one third of households in Ronneby, Sweden. The source was firefighting foam used a nearby airfield since the mid-1980s. Clean provided from December 16, 2013. purpose estimate serum half-lives their determinants study population different PFAS. Up ten blood samples were collected between 2014 2018 114 participants (age...
The European Commission asked EFSA to update its 2009 risk assessment on arsenic in food carrying out a hazard of inorganic (iAs) and using the revised exposure issued by 2021. Epidemiological studies show that chronic intake iAs via diet and/or drinking water is associated with increased several adverse outcomes including cancers skin, bladder lung. CONTAM Panel used benchmark dose lower confidence limit based response (BMR) 5% (relative increase background incidence after adjustment for...
The London smog of 1952 is one history's most important air pollution episodes in terms its impact on science, public perception pollution, and government regulation. association between health during the episode was evident as a strong rise levels immediately followed by sharp increases mortality morbidity. However, months after also elevated above normal levels. An initial report proposed hypothesis that influenza responsible for high these months. Estimates number deaths were generated...