A5029169901- Wastewater Treatment and Nitrogen Removal
- Microbial Fuel Cells and Bioremediation
- Microbial Community Ecology and Physiology
- Microbial bioremediation and biosurfactants
- Microbial metabolism and enzyme function
- Advanced Malware Detection Techniques
- Metalloenzymes and iron-sulfur proteins
- Network Security and Intrusion Detection
- Microbial Metabolic Engineering and Bioproduction
- Legume Nitrogen Fixing Symbiosis
- Adversarial Robustness in Machine Learning
- Enzyme Catalysis and Immobilization
- Genomics and Phylogenetic Studies
- Algal biology and biofuel production
- Electrochemical sensors and biosensors
- Nitric Oxide and Endothelin Effects
- Anomaly Detection Techniques and Applications
- Ammonia Synthesis and Nitrogen Reduction
- Metal-Catalyzed Oxygenation Mechanisms
- Electrocatalysts for Energy Conversion
- Internet Traffic Analysis and Secure E-voting
- Chemical Reactions and Isotopes
- Hydrogen Storage and Materials
- Anaerobic Digestion and Biogas Production
- Cassava research and cyanide
Technische Universität Berlin
2012-2024
Technische Universität Braunschweig
2016-2020
Oregon State University
2007-2019
University of Göttingen
2013-2015
Lawrence Livermore National Laboratory
2003-2007
Institute of Crop Science
2005
Joint Genome Institute
2003
Oak Ridge National Laboratory
2003
Utah State University
2003
University of Louisville
2003
Malicious applications pose a threat to the security of Android platform. The growing amount and diversity these render conventional defenses largely ineffective thus smartphones often remain unprotected from novel malware. In this paper, we propose DREBIN, lightweight method for detection malware that enables identifying malicious directly on smartphone. As limited resources impede monitoring at run-time, DREBIN performs broad static analysis, gathering as many features an application...
Ammonia-oxidizing archaea are ubiquitous in marine and terrestrial environments now thought to be significant contributors carbon nitrogen cycling. The isolation of Candidatus “ Nitrosopumilus maritimus ” strain SCM1 provided the opportunity for linking its chemolithotrophic physiology with a genomic inventory globally distributed archaea. Here we report 1,645,259-bp closed genome SCM1, revealing highly copper-dependent systems ammonia oxidation electron transport that distinctly different...
The vast majority of security breaches encountered today are a direct result insecure code. Consequently, the protection computer systems critically depends on rigorous identification vulnerabilities in software, tedious and error-prone process requiring significant expertise. Unfortunately, single flaw suffices to undermine system thus sheer amount code audit plays into attacker's cards. In this paper, we present method effectively mine large amounts source for vulnerabilities. To end,...
Nitrosomonas europaea (ATCC 19718) is a gram-negative obligate chemolithoautotroph that can derive all its energy and reductant for growth from the oxidation of ammonia to nitrite. participates in biogeochemical N cycle process nitrification. Its genome consists single circular chromosome 2,812,094 bp. The GC skew analysis indicates divided into two unequal replichores. Genes are distributed evenly around genome, with approximately 47% transcribed one strand 53% complementary strand. A total...
The number of malicious applications targeting the Android system has literally exploded in recent years. While security community, well aware this fact, proposed several methods for detection malware, most these are based on permission and API usage or identification expert features. Unfortunately, many approaches susceptible to instruction level obfuscation techniques. Previous research classic desktop malware shown that some high characteristics code, such as function call graphs, can be...
To cope with the increasing variability and sophistication of modern attacks, machine learning has been widely adopted as a statistically-sound tool for malware detection. However, its security against well-crafted attacks not only recently questioned, but it shown that exhibits inherent vulnerabilities can be exploited to evade detection at test time. In other words, itself weakest link in system. this paper, we rely upon previously-proposed attack framework categorize potential scenarios...
Despite the security community's best effort, number of serious vulnerabilities discovered in software is increasing rapidly. In theory, audits should find and remove before code ever gets deployed. However, due to enormous amount being produced, as well a lack manpower expertise, not all sufficiently audited. Thus, many slip into production systems. A best-practice approach use metric analysis tool, such Flawfinder, flag potentially dangerous so that it can receive special attention....
Ammonia monooxygenase of Nitrosomonas europaea catalyzes the oxidation alkanes (up to C 8 ) alcohols and alkenes 5 epoxides in presence ammonium ions. Straight-chain, N-terminal alkynes 10 all exhibited a time-dependent inhibition ammonia without effects on hydrazine oxidation.
The complete genome of the ammonia-oxidizing bacterium Nitrosospira multiformis (ATCC 25196(T)) consists a circular chromosome and three small plasmids totaling 3,234,309 bp encoding 2,827 putative proteins. Of proteins, 2,026 proteins have predicted functions 801 are without conserved functional domains, yet 747 these similarity to other in databases. Gene homologs from Nitrosomonas europaea eutropha were best match for 42% genes N. multiformis. contains nearly identical copies amo hao gene...
Benzene and a variety of substituted benzenes inhibited ammonia oxidation by intact cells Nitrosomonas europaea. In most cases, the inhibition was accompanied transformation aromatic compound to more oxidized product or products. All products detected were aromatic, substituents often but not separated from benzene ring. Most transformations enhanced (NH 4 ) 2 SO (12.5 mM) prevented C H , mechanism-based inactivator monooxygenase (AMO). AMO catalyzed alkyl substituent hydroxylations, styrene...
The ammonia-oxidizing archaea have recently been recognized as a significant component of many microbial communities in the biosphere. Although overall stoichiometry archaeal chemoautotrophic growth via ammonia (NH 3 ) oxidation to nitrite (NO 2 − is superficially similar bacteria, genome sequence analyses point completely unique biochemistry. only genomic signature linking bacterial and biochemistries NH highly divergent homolog monooxygenase (AMO). presumptive product putative AMO...
Incubation of cells the nitrifying bacterium Nitrosomonas europaea with 14C2H2 results in covalent attachment 14C label to a membrane-bound polypeptide an approximate Mr 28,000 (Hyman, M.R., and Wood, P.M. (1985) Biochem. J. 227, 719-725). A labeling procedure using generated from Ba14CO3 has been used investigate correlation between extent modification this by level ammonia oxidizing activity whole cells. The time-dependent inactivation monooxygenase resulted progressive saturable...
The soil nitrifying bacterium Nitrosomonas europaea is capable of degrading trichloroethylene (TCE) and other halogenated hydrocarbons. TCE cometabolism by N. resulted in an irreversible loss biodegradative capacity, ammonia-oxidizing activity, ammonia-dependent O(2) uptake the cells. Inactivation was not observed presence allylthiourea, a specific inhibitor enzyme ammonia monooxygenase, or under anaerobic conditions, indicating that TCE-mediated inactivation required monooxygenase activity....
The effect of copper on the in vivo and vitro activity ammonia monooxygenase (AMO) from nitrifying bacterium Nitrosomonas europaea was investigated. addition CuCl2 to cell extracts resulted 5- 15-fold stimulation ammonia-dependent O2 consumption, nitrite production, hydrazine-dependent ethane oxidation. AMO further stimulated by presence stabilizing agents, including serum albumins, spermine, or MgCl2. In contrast, agents whole-cell suspensions did not result any activity. use AMO-specific...
ABSTRACT Ammonia (NH 3 )-oxidizing bacteria (AOB) and thaumarchaea (AOA) co-occupy most soils, yet no short-term growth-independent method exists to determine their relative contributions nitrification in situ . Microbial monooxygenases differ vulnerability inactivation by aliphatic n -alkynes, we found that NH oxidation the marine thaumarchaeon Nitrosopumilus maritimus was unaffected during a 24-h exposure ≤20 μM concentrations of 1-alkynes C 8 9 In contrast, two AOB ( Nitrosomonas europaea...
ABSTRACT The alphaproteobacterium Nitrobacter winogradskyi (ATCC 25391) is a gram-negative facultative chemolithoautotroph capable of extracting energy from the oxidation nitrite to nitrate. Sequencing and analysis its genome revealed single circular chromosome 3,402,093 bp encoding 3,143 predicted proteins. There were extensive similarities genes in two alphaproteobacteria, Bradyrhizobium japonicum USDA110 (1,300 genes) Rhodopseudomonas palustris CGA009 CG (815 genes). Genes pathways for...
Summary Analysis of the structure and inventory genome Nitrosomonas eutropha C91 revealed distinctive features that may explain adaptation N. ‐like bacteria to N‐saturated ecosystems. Multiple gene‐shuffling events are apparent, including mobilized replicated transposition, as well plasmid or phage integration into 2.66 Mbp chromosome two plasmids (65 56 kbp) C91. A 117 kbp genomic island encodes multiple genes for heavy metal resistance, clusters copper mercury transport, which absent from...
Nitrobacter winogradskyi Nb-255 is a nitrite-oxidizing bacterium that can grow solely on nitrite (NO2(-)) as source of energy and nitrogen. In most natural situations, NO2(-) oxidation coupled closely to ammonium (NH4(+)) by bacteria archaea and, conceptually, N. save using NH4(+) meet its N-biosynthetic requirements. Interestingly, delayed the growth when at concentrations higher than 35 mM, but grew well below 25 mM while adjusting expression 24% genes. Notable genes changed in included...
Deep learning is increasingly used as a building block of security systems. Unfortunately, neural networks are hard to interpret and typically opaque the practitioner. The machine community has started address this problem by developing methods for explaining predictions networks. While several these approaches have been successfully applied in area computer vision, their application received little attention so far. It an open question which explanation appropriate what requirements they...