Hidetoshi Hamada

ORCID: 0000-0003-3652-9400
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About
Contact & Profiles
Research Areas
  • Orthopaedic implants and arthroplasty
  • Hip disorders and treatments
  • Total Knee Arthroplasty Outcomes
  • Bone and Joint Diseases
  • Orthopedic Infections and Treatments
  • Hip and Femur Fractures
  • Bone health and osteoporosis research
  • Bone health and treatments
  • Pelvic and Acetabular Injuries
  • Lower Extremity Biomechanics and Pathologies
  • Shoulder Injury and Treatment
  • Xenotransplantation and immune response
  • Osteoarthritis Treatment and Mechanisms
  • Advanced X-ray and CT Imaging
  • Body Composition Measurement Techniques
  • Cardiac Valve Diseases and Treatments
  • Drug Transport and Resistance Mechanisms
  • Spine and Intervertebral Disc Pathology
  • Shoulder and Clavicle Injuries
  • Bone fractures and treatments
  • Nutrition and Health in Aging
  • Medical Imaging Techniques and Applications
  • Sports Dynamics and Biomechanics
  • Pregnancy-related medical research
  • Virus-based gene therapy research

Osaka University
2015-2025

Osaka University Hospital
2021

Nagoya University
1997-2020

Creative Commons
2018

Clinical Orthopaedics and Related Research
2018

Ministry of Health Labour and Welfare
2018

University of Miyazaki
2015-2017

Chiba University
2017

Aichi Institute of Technology
2017

Hiroshima University
2000

170-180-kDa membrane glycoprotein (P-glycoprotein) associated with multidrug resistance is involved in drug transport mechanisms across the plasma of resistant cells. From sequence analysis cDNAs P-glycoprotein gene, it postulated that active drug-efflux pump function may be attributable to protein. However, purification while preserving its enzymatic activity has not been reported. In this study, we have purified from human myelogenous leukemia K562 cell line adriamycin (K562/ADM) by means...

10.1016/s0021-9258(19)57324-0 article EN cc-by Journal of Biological Chemistry 1988-01-01

The clinical features of 166 patients with ossification the posterior longitudinal ligament are reported. Symptoms cervical myelopathy develop and include difficulty walking sensory motor disturbances. Roentgenograms disclose dense to vertebral bodies, symtoms most often observed when occupies more than 60% saggital diameter canal. Posterior decompression is effective surgical treatment. Two ankylosing spinal hypertosis expired necropsy was performed. histologic spine cord described.

10.1097/00007632-197706000-00005 article EN Spine 1977-06-01

Abstract Background Many studies have confirmed that the size and location of necrotic lesions are major factors affect prevalence collapse prognosis in patients with osteonecrosis femoral head (ONFH). Although several classification systems categorize quantify ONFH, there is no agreement on which one most useful for purpose. Questions/purposes We compared Steinberg, modified Kerboul, Japanese Investigation Committee (JIC) classifications ONFH terms (1) correlation among three different...

10.1007/s11999.0000000000000245 article EN cc-by-nc-nd Clinical Orthopaedics and Related Research 2018-03-15

The optimal reorientation of the acetabulum for developmental dysplasia hip (DDH) is unknown in terms range-of-motion (ROM). simulated ROMs 52 DDHs after rotational acetabular osteotomy (RAO) with several patterns femoral head coverage and those 73 normal hips were analyzed using computer models reconstructed from CT images. After RAO a lateral center edge angle (LCEA) 30° an anterior (ACEA) 55° producing similar to that hips, maximal flexion internal rotation at 110° 20° adduction...

10.1002/jor.23024 article EN Journal of Orthopaedic Research® 2015-08-11

Pelvic sagittal inclination (PSI) significantly affects the femoral head coverage by acetabulum in patients with developmental dysplasia of hip (DDH), while no reports have quantified PSI DDH supine and standing positions. Furthermore, little is known about how changes after periacetabular osteotomies. Herein, positions was preoperatively postoperatively. Twenty-five who had undergone osteotomies were analyzed. The preoperative 2 years surgery measured using image registration technique...

10.1002/jor.24484 article EN publisher-specific-oa Journal of Orthopaedic Research® 2019-09-27

Postthoracotomy pain syndrome is generally considered to be neuropathic due intercostal nerve injury. However, nonneuropathic can also occur following thoracic surgery. We present a series of cases with postthoracotomy in which myofascial was thought causative component syndrome.Twenty-seven patients (17 men and 10 women) were treated trigger point injections, blocks, and/or epidural blocks. Clinical criteria used diagnose the pain. A visual analogue scale used, sensory disturbances recorded...

10.1016/s1098-7339(00)90016-6 article EN Regional Anesthesia & Pain Medicine 2000-06-01

The aim of this study was to examine whether hips with unilateral osteoarthritis (OA) secondary developmental dysplasia the hip (DDH) have significant asymmetry in femoral length, and determine potential related factors.We enrolled 90 patients (82 female, eight male) DDH showing OA changes, 43 healthy volunteers (26 17 as controls. mean age 61.8 years (39 93) for groups, 71.2 (57 84) control group. Using a CT-based coordinate measurement system, we evaluated following vertical distances: top...

10.1302/0301-620x.101b3.bjj-2018-0965.r1 article EN The Bone & Joint Journal 2019-02-28

Objective The aim of this study was to elucidate the efficacy T2-mapping MRI and correlation with histology for evaluation tissue repair quality following first-in-human implantation an autologous engineered construct. Design We directly compared results cartilage a biopsy specimen from corresponding area at 48 weeks postoperatively in 5 patients who underwent scaffold-free tissue-engineered construct generated synovial mesenchymal stem cells isolated lesion. T2 values histological scores...

10.1177/1947603521989423 article EN Cartilage 2021-01-29

Diagnosis and treatment of osteoporosis are instrumental in obtaining good outcomes hip surgery. Measuring bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA) is the gold standard for diagnosing osteoporosis. However, due to limited access DXA, there a need screening tool identify patients at higher risk We analyzed potential utility Osteoporosis Self-assessment Tool Asians (OSTA) as A total 1378 female who underwent surgery 8 institutions were analyzed. For each patient,...

10.1016/j.afos.2024.01.003 article EN cc-by Osteoporosis and Sarcopenia 2024-03-01

Aims Femoral component anteversion is an important factor in the success of total hip arthroplasty (THA). This retrospective study aimed to investigate accuracy femoral with Mako THA system and software using Exeter cemented component, compared Accolade II cementless component. Methods We reviewed data 30 hips from 24 patients who underwent posterior approach components, components. Both groups did not differ significantly age, sex, BMI, bone quality, or disease. Two weeks postoperatively,...

10.1302/0301-620x.106b3.bjj-2023-0840.r1 article EN The Bone & Joint Journal 2024-03-01
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