A5102809690- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Genetics and Neurodevelopmental Disorders
- Congenital Anomalies and Fetal Surgery
- Genomics and Rare Diseases
- Asthma and respiratory diseases
- Prenatal Screening and Diagnostics
- Sex and Gender in Healthcare
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Career Development and Diversity
- Bone fractures and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Genetic Syndromes and Imprinting
- Spinal Dysraphism and Malformations
- Neurogenetic and Muscular Disorders Research
- Bone and Joint Diseases
- Bone health and treatments
Centre Hospitalier Universitaire Sainte-Justine
2024
Université de Montréal
2018-2024
GlaxoSmithKline (Canada)
2020
University of Ottawa
2014
Purpose: To assess the pregnancy outcomes of women with spina bifida.Materials and methods: We analyzed a population-based cohort 397 pregnant bifida 1,083,211 without who delivered infants in hospitals Quebec, Canada, 1989-2013. Outcomes included maternal infant morbidity mortality at delivery. used log-binomial regression models to estimate prevalence ratios (PR) 95% confidence intervals (CI) for association outcomes, accounting characteristics.Results: Women had higher several adverse...
Abstract Background Cohorts of childhood acute lymphoblastic leukemia (cALL) survivors reaching adulthood are increasing. Approximately 30% meet criteria for low bone mineral density (BMD) 10 years after diagnosis. We investigated risk factors BMD in long‐term cALL survivors. Methods recruited 245 from the PETALE (Prévenir les effets tardifs des traitements de la leucémie aiguë lymphoblastique chez l'enfant) cohort, who were treated with Dana Farber Cancer Institute protocols, did not...
Aim: To identify genetic markers associated with late treatment-related skeletal morbidity in survivors of childhood acute lymphoblastic leukemia (ALL). Patients & methods: this end, we measured the association between reduction bone mineral density or vertebral fractures prevalence and variants from 1039 genes derived through whole exome sequencing 242 ALL survivors. Top-ranking were confirmed genotyping, further explored stratified analyses multivariable models. Results: The minor allele...
Emerging fields such as environmental health have been challenged, in recent years, to answer the growing methodological calls for a finer integration of sex and gender health-related research policy-making. Through descriptive examination 25 peer-reviewed social science papers published between 1996 2011, we explore, by examining designs theoretical standpoints, how sciences integrated sensitivity empirical work on Multiple Chemical Sensitivities (MCS). MCS is "diagnosis" associated with...
Background: Although 80% of childhood acute lymphoblastic leukemia (ALL) cases are cured with current treatment protocols, exposure to chemotherapeutics or radiation therapy during a vulnerable period child development has been associated high frequency late adverse effects (LAE). Previous observations suggest important skeletal muscle size, density and function deficits in ALL survivors. Purpose: Given that only fraction all patients will suffer from this particular complication, we...
Childhood acute lymphoblastic leukemia (cALL) survivors are at increased risk for bone comorbidities, but accurate screening tools such comorbidities limited. Polygenic scores (PGS) could stratify cALL of long-term adverse outcomes. We evaluated 214 (51% female) from the Prévenir les Effets TArdifs de la LEucémie study (median age 21 yr). Bone mineral density (BMD) measurements were obtained using dual X-ray absorptiometry lumbar spine (LS-BMD), femoral neck (FN-BMD), and total body...
Searchable abstracts of presentations at key conferences on calcified tissues ISSN 2052-1219 (online)