A5065889241- Childhood Cancer Survivors' Quality of Life
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular and exercise physiology
- Acute Lymphoblastic Leukemia research
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Nutrition and Health in Aging
- Cardiac Ischemia and Reperfusion
- Cardiac Imaging and Diagnostics
- Family Support in Illness
- Cardiac Arrest and Resuscitation
- Adolescent and Pediatric Healthcare
- Cardiovascular Effects of Exercise
- Cardiac Health and Mental Health
- ECG Monitoring and Analysis
- Birth, Development, and Health
- Children's Physical and Motor Development
- Cancer survivorship and care
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Family and Disability Support Research
- Kawasaki Disease and Coronary Complications
- Anesthesia and Neurotoxicity Research
Centre Hospitalier Universitaire Sainte-Justine
2016-2025
Université de Montréal
2016-2025
Penn State Milton S. Hershey Medical Center
2024
Pennsylvania State University
2024
Université du Québec à Montréal
2020
Weatherford College
2019
Centre Hospitalier de l’Université de Montréal
2013-2016
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2015
Université Laval
2015
Dornier Flugzeugwerke (Germany)
2015
The purpose of this study was to evaluate cardiac autonomic modulation in university athletes during the post-acute late phase (mean, 95 days ±63) injury at rest and physical exertion. We also sought effect time since number injuries on heart rate variability (HRV). hypothesized that exertion would reveal persisting modifications HRV following a concussion. included, cross-sectional design, who sustained concussion matched controls. Concussions were identified by medical doctor using...
Abstract Background Childhood cancer survivorship issues represent an established public health challenge. Most late adverse effects (LAEs) have been demonstrated to be time and treatment dependent. The PETALE study is a multidisciplinary research project aiming comprehensively characterize LAEs identify associated predictive biomarkers in childhood acute lymphoblastic leukemia (cALL) survivors. Methods cALL survivors treated at Sainte‐Justine University Health Center with Dana‐Farber Cancer...
Remote ischemic preconditioning (RIPC) provides a substantial benefit for heart protection during surgery. Recent literature on RIPC reveals the potential to enhancement of sports performance as well. The aim this study was investigate effect anaerobic performance. Seventeen healthy participants who practice regular physical activity participated in project (9 women and 8 men, mean age 28 ± years). were randomly assigned an intervention (four 5-minute cycles ischemia reperfusion, followed by...
Accumulating research indicates that the regular practice of physical exercise is beneficial to human brain. From improvement academic achievement in children prevention Alzheimer’s disease elderly, appears across developmental spectrum. Recent work from animal studies also a pregnant mother can transfer benefits during gestation her offspring’s Exercising rats give birth pups have better memory and spatial learning as well increased synaptic density. To investigate whether this child occurs...
Preterm birth incurs an increased risk of early cardiovascular events and death. In the general population, factors cluster in context inflammation oxidative stress. Whether this also occurs young adults born preterm is unknown. We analyzed 101 healthy (ages 18–29) (≤29 weeks gestation) 105 full-term controls, predominantly (90%) white. They underwent a comprehensive clinical biological evaluation, including measurement blood pressure, lung function (spirometry), glucose metabolism (fasting...
Most childhood acute lymphoblastic leukemia (ALL) survivors develop chronic treatment-related adverse effects several years after the end of therapy. A regular practice physical activity and a good cardiorespiratory fitness have potential to reduce risk disease improve quality life. The aim this study was evaluate in cohort ALL survivors, association between or respect guidelines major long-term health outcomes.In total, 247 underwent cardiopulmonary exercise test, completed questionnaire...
Background/Objectives: Pediatric cancer survivors are at greater risk of cardiometabolic complications than their peers. This study evaluates the preliminary impact VIE (Valorization, Implication, Education) intervention, which integrates nutrition, physical activity, and psychological support, on dietary intake health among children adolescents during treatment. Methods: comparative includes pediatric patients recruited to either intervention group or a control receiving standard care....
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Contributory factors such as inflammation and oxidative stress, in response to drug therapies, may induce premature aging cellular senescence with a severe impact on cardiometabolic health. Premature immunoaging through can lead lower thymic output of T-cell lymphocytes translated into circulating receptor excision circles (TRECs). We hypothesized TRECs levels are associated diet quality impacted by inflammatory status...
UFR-STAPS, Laboratoire Activité Physique et Santé, Université Paul Sabatier, Toulouse, France (Dr Curnier); the University of Vermont, College Medicine (Mr Savage and Dr Ades) McClure 1, Cardiology, Fletcher-Allen Health Care Ades), Burlington, VT. Address correspondence to: Philip A. Ades, MD, Care, VT 05401 (e-mail: [email protected]).
Preterm birth is linked to cardiovascular risks and diseases. Endothelial progenitor cells play a critical role in vascular development repair. Cord blood endothelial of preterm-born infants, especially colony-forming (ECFC), show enhanced susceptibility prematurity-related pro-oxidant stress. Whether ECFC dysfunction present adulthood following preterm unknown.
This study aims to describe the feasibility of a nutritional intervention that promotes healthy eating habits early after cancer pediatric diagnosis in patients and their parents. Participants were recruited 4 12 weeks as part VIE study. The one-year included an initial evaluation 6 follow-up visits every 2 months with registered dietician. assessment rates retention, participation, attendance, completion measures, participants' engagement. A preliminary intervention's impact on dietary...
Childhood acute lymphoblastic leukemia (cALL) survivors suffer early-onset chronic diseases classically associated with aging. Normal aging is accompanied by organ dysfunctions, including immunological ones. We hypothesize that thymic immunosenescence occurs in cALL and its severity may correlate diseases. The PETALE study a survivor cohort an extensive cardiovascular metabolic evaluation. biomarker, signal joint T-cell receptor excision circles (TREC), was evaluated highly correlated age...
Introduction: As the survival rate of childhood acute lymphoblastic leukemia (ALL) continues to improve, physical deconditioning is becoming an increasingly common problem in survivors. The aim this study was compare cardiorespiratory fitness and activity levels survivors control participants. Methods: A total 221 ALL (114 males 107 females), diagnosed between 1987 2010 treated according Dana Farber Cancer Institute-ALL 87-01 05-01 protocols at Sainte-Justine University Health Center...
Introduction: More than two thirds of survivors have long-term adverse effects, and no study proposes a portrait physical activity level in childhood acute lymphoblastic leukemia survivors. The aims this were to present the cardiorespiratory fitness (CRF) levels detailed overview sedentary activities portrait. Methods: A total 247 included our study. Survivors underwent cardiopulmonary exercise test on ergocycle completed questionnaires assess their leisure daily energy expenditure. Results:...
This study aims to compare cardiopulmonary response aerobic exercise between young adults born very preterm, including a subgroup with bronchopulmonary dysplasia (BPD), and term controls. Seventy-one (18–29 years) <30 weeks’ gestational age (24 BPD) 73 controls were recruited. Assessment included testing impedance cardiography. We compared group differences in peak O 2 consumption (peak VO ) ventilatory cardiovascular responses using linear regression analyses. Preterm participants had...