A5066445320- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Metal complexes synthesis and properties
- Organometallic Complex Synthesis and Catalysis
- Magnetism in coordination complexes
- Click Chemistry and Applications
- Luminescence and Fluorescent Materials
- Synthesis and Catalytic Reactions
- Catalytic C–H Functionalization Methods
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Organic Light-Emitting Diodes Research
- Crystal structures of chemical compounds
- Oxidative Organic Chemistry Reactions
- Synthesis and Reactions of Organic Compounds
- Catalytic Cross-Coupling Reactions
- Synthesis and Characterization of Pyrroles
- Carbon dioxide utilization in catalysis
- Synthesis and Reactivity of Heterocycles
- Metal-Organic Frameworks: Synthesis and Applications
- Cyclopropane Reaction Mechanisms
- Metal-Catalyzed Oxygenation Mechanisms
- Organic Chemistry Cycloaddition Reactions
- Organoboron and organosilicon chemistry
- Synthesis and biological activity
Universidade Nova de Lisboa
2019-2025
University of Lisbon
2014-2024
Rede de Química e Tecnologia
2015-2024
Universidade Federal do Espírito Santo
2024
Unidade em Ciências Biomoleculares Aplicadas
2021-2023
Faculdade de Tecnologia e Ciências
2019-2021
Instituto Superior Técnico
2010-2020
Instituto Politécnico de Lisboa
2011-2020
Laboratório Associado para a Química Verde
2019
University of Coimbra
2002-2017
The first examples of Ru(II) h6-arene (benzene and p-cymene) complexes containing a bidentate triazolylidene-triazolide ligand have been prepared fully characterized. Their antiproliferative effect has investigated against tumour cells A2780 (ovarian carcinoma), HCT116 (colorectal HCT116dox carcinoma resistant to doxorubicin), in human dermal fibroblasts. Ru complex bearing the p-cymene arene group exhibited stronger across all tested cell lines, while benzene-containing displayed higher...
New bis- and tris(iminopyrrole)-functionalized linear (1,2-(HNC4 H3 -C(H)N)2 -C6 H4 (2), 1,3-(HNC4 (3), 1,4-(HNC4 (4), 4,4'-(HNC4 -(C6 ) (5), 1,5-(HNC4 C-(H)N)2 -C10 H6 (6), 2,6-(HNC4 (7), -C14 H8 (8)) star-shaped (1,3,5-(HNC4 -C(H)N-1,4-C6 )3 (9)) π-conjugated molecules were synthesized by the condensation reactions of 2-formylpyrrole (1) with several aromatic di- triamines. The corresponding diboron chelate complexes (Ph2 B[1,3-bis(iminopyrrolyl)-phenyl]BPh2 (10), Ph2...
New 2-iminophenanthro[9,10-c]pyrrole ligand precursors containing phenyl or 2,6-diisopropylphenyl groups at the imine nitrogen substituent, 2-arylformiminophenanthro[9,10-c]pyrroles (aryl = IIa, IIb) were synthesized and deprotonated in situ with NaH, originating solutions of corresponding sodium salts (IVa, IVb). The reaction these zinc chloride gave homoleptic bis-ligand Zn(II) complexes [Zn(kappa(2)N,N'-2-arylformiminophenanthro[9,10-c]pyrrolyl)(2)] 2a, 2b). new characterized by NMR,...
Efficient non-doped OLEDs have been achieved using new binuclear tetracoordinate organoboron complexes containing 2-(N-aryl)formiminopyrrolyl ligands.
Synthesis, structure and reactivity of<sc>v</sc>(<sc>iv</sc>/<sc>v</sc>) complexes involving DMSO assisted methylation of thiosemicarbazone.
The condensation reactions of 2-formylindole (1) or 2-formylphenanthro[9,10-c]pyrrole (2) with various aromatic amines afforded the corresponding phenyl phenanthrene ring fused mono-/bis-iminopyrrole ligand precursors 3-8, which, upon reaction BPh3 in an appropriate molar ratio, led to new mono- and diboron chelate compounds Ph2B[NC8H5C(H)[double bond, length as m-dash]N-2,6-Ar] (Ar = 2,6-iPr2C6H39; C6H510), Ph2B[(NC8H5C(H)[double m-dash]N)2-1,4-C6H4]BPh211, Ph2B(NC16H9C(H)[double...
A new family of air-stable Mn and Re complexes bearing bidentate bis(1,2,3-triazol-5-ylidene) ligands with the general formula [M(bis-triazolylidene)(CO)3X] (M = or Re; X Cl Br), containing a methylene linker direct link between two triazolylidene ligands, is presented. All have been applied as catalysts for N-alkylation anilines benzylic alcohols. The complex bis-triazolylidene bridge fragments was shown to be highly efficient catalyst, affording corresponding amine in 92% yield presence...
A series of zinc complexes the general formula {[ZnCl(ArNC(An)–C(An)NAr)]+}2[Zn2Cl6]2− (where Ar = 2-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl 2a, 2-(1-(1-phenylethyl)-1H-1,2,3-triazol-4-yl)phenyl 2b, 2-(1-phenyl-1H-1,2,3-triazol-4-yl)phenyl 2c; An acenaphthene backbone) were prepared by condensation acenaphthenequinone with corresponding o-triazolyl-substituted anilines (2-(1-benzyl-1H-1,2,3-triazol-4-yl)aniline 1a, 2-(1-(1-phenylethyl)-1H-1,2,3-triazol-4-yl)aniline 1b,...
Abstract Reactions of 2‐( N ‐arylimino)pyrroles (HNC 4 H 3 C(H)N‐Ar) with triphenylboron (BPh ) in boiling toluene afford the respective highly emissive , ′‐boron chelate complexes, [BPh 2 {κ N′ ‐NC C(H)N‐Ar}] (Ar=C 6 5 ( 12 ), 2,6‐Me ‐C 13 2,6‐ i Pr 14 4‐OMe‐C 15 3,4‐Me 16 4‐F‐C 17 4‐NO 18 4‐CN‐C 19 3,4,5‐F 20 and C F 21 )) moderate to high yields. The photophysical properties these new boron complexes largely depend on substituents present aryl rings their ‐arylimino moieties. bearing...
A new family of hypervalent iodine reagents containing transferable primary amine groups is described. Benziodoxolone-based were synthesized on the gram-scale through operationally simple reactions in up to quantitative yields. These bench-stable solids characterized by X-ray analysis and successfully employed α-amination indanone-based β-ketoesters 83% yield. Mechanistic studies indicate a substitution mechanism involving an electrophilic amine.
Iminopyrrolyl complexes of sodium were prepared from the reaction 2-arylformiminopyrrole ligand precursors (aryl = C(6)H(5) (I); 2,6-Me(2)C(6)H(3) (II); 2,4,6-Me(3)C(6)H(2) (III); 2,6-(i)Pr(2)C(6)H(3) (IV)) with one equivalent hydride. The resulting corresponding compounds 1-4, [{Na(mu(2):kappa(2)N,N'-iminopyrrolyl)}(2n)(OEt(2))(2x)] (n > or 1; x 0 1), obtained in moderate to high yields and characterised by NMR spectroscopy, resolution mass spectrometry X-ray diffraction, when suitable...
Abstract A series of new cationic and neutral (Ar‐BIAN)copper(I) complexes [in which Ar‐BIAN = bis(aryl)acenaphthenequinonediimine] was synthesised characterised by elemental analysis, 1D 2D NMR spectroscopy single‐crystal X‐ray diffraction. The the general formula [Cu(Ar‐BIAN) L 2 ]BF 4 [ (PPh 3 ) ( 1 ), dppe dppf (AsPh ); Ar 4‐ i PrC 6 H a 4‐MeOC b 4‐NO C c 2‐ d Ph PCH CH PPh (dppe), (Ph PC 5 Fe (dppf)] were reaction [Cu(EPh (E P or As) equimolar amounts ligands, [Cu(NCMe) , ‐BIAN...
New substituted 5-aryl-2-(N-2,6-diisopropylphenylformimino)-1H-pyrrole ligand precursors reacted with the complex trans-[Ni(o-C6H4Cl)(PPh3)2Cl] to give rise new mono(2-iminopyrrolyl) nickel(II) complexes general formula [Ni{κ2N,N′-5-aryl-NC4H2-2-C(H)═N-2,6-iPr2C6H3}(o-C6H4Cl)(PPh3)]. The pyrrole 5-aryl substituent is a phenyl or bulky anthracen-9-yl ring, first being also modified by para-substituents electron-releasing (methoxy) electron-withdrawing (fluorine) characteristics. compounds...
The reactivity of nitrosoalkenes toward dipyrromethanes, pyrrole, and 2,5-dimethylpyrrole is described. 1-(p-Bromophenyl)nitrosoethylene shows a different chemical behavior with these heterocycles than the previously reported reactions ethyl nitrosoacrylate, which proceeds via Diels-Alder reaction. reacts dipyrromethanes pyrrole to afford two isomeric oximes conjugate addition followed by rearomatization unit. On other hand, this nitrosoalkene through an initial intramolecular O-...
Two new Ar-BIAN Cu(II) complexes (where = bis(aryl-imino)acenaphthene) of formulations [CuCl2(Mes-BIAN)] (1) (Mes 2,4,6-Me3C6H2) and [CuCl2(Dipp-BIAN)] (2) (Dipp 2,6-iPr2C6H3) were synthesised by direct reaction CuCl2 suspended in dichloromethane with the respective ligands Mes-BIAN (L1) Dipp-BIAN (L2), dissolved dichloromethane, under an argon atmosphere. Attempts to obtain these compounds solubilising methanol adding a solution corresponding ligand, aerobic conditions, gave also compound...
A family of mono(2-iminopyrrolyl) complexes with the general formula [Ni{κ2N,N'-5-(aryl)-NC4H2-2-C(H)[double bond, length as m-dash]N-2,6-(aryl)}(C6H5)(PPh3)] were obtained from reaction sodium salts newly synthesised 5-aryl-2-(N-arylformimino)pyrroles square planar complex trans-[Ni(C6H5)(PPh3)2Cl]. These new iminopyrrole ligand precursors, designed increasing bulkiness and different electronic properties, their corresponding nickel(ii) characterised by NMR spectroscopy elemental analysis,...
A group of new mononuclear boron chelate compounds [BPh2{κ2N,N'-5-R-NC4H2-2-C(H)[double bond, length as m-dash]N-Ar}] (R = Ar C6H57; R C6H5, 2,6-iPr2C6H38; Anthracen-9-yl (Anthr), C6H59; Anthr, 2,6-iPr2C6H310) were synthesized via the reaction B(C6H5)3 with corresponding 5-substituted 2-(N-arylformimino)pyrrole ligand precursors 3-6. These complexes prepared in order to evaluate luminescence potential derived from substitution position 5 pyrrolyl ring an aromatic group. Compounds 7-10...
A series of new fac-[Mn(L)(CO)3Br] complexes where L is a bidentate chelating ligand containing mixed mesoionic triazolylidene-pyridine (MIC^py, 1), triazolylidene-triazole (MIC^trz, 2), and triazole-pyridine (trz^py, 3) ligands have been prepared fully characterized, including the single crystal X-ray diffraction studies 1 2. The abilities 1-3 complex fac-[Mn(MIC^MIC)(CO)3Br] (4) to catalyze electroreduction CO2 has assessed for first time. It was found that all displayed current increase...
In the present work, several coumarin-3-carboxamides with different azacrown ether moieties were designed and tested as potential luminescent sensors for metal ions. The derivative containing a 1-aza-15-crown-5 chelating group was found to yield strongest response Ca2+ Pb2+, exhibiting an eight- nine-fold emission increase, respectively, while other cations induced no changes in optical properties of chemosensor molecule. Job’s plots revealed 1:1 binding stoichiometry, association constants...
This study reveals two new spin crossover Fe( iii ) compounds, analyses their structural and magnetic properties together with halogen substitution effects, highlights the role of in crossover, guiding future molecular design.
Herein we report the first examples of 1,3-dipolar cycloadditions thiazolidine-derived sydnones with benzyne leading to 1,3-dihydrothiazolo[3,4-b]indazoles. These heterocycles were converted into corresponding sulfones which used as precursors novel benzo-2,3-diazafulvenium methides. reactive intermediates reacted N-substituted maleimides affording new 1H-indazoles characterized by an intense yellow color, a property that gives them potential application dyes. The synthesis these was...