A5036720827- Veterinary Oncology Research
- Parasitic Infections and Diagnostics
- Virus-based gene therapy research
- Amoebic Infections and Treatments
- Characterization and Applications of Magnetic Nanoparticles
- Fibroblast Growth Factor Research
- Reproductive Physiology in Livestock
- Wnt/β-catenin signaling in development and cancer
- Nanoparticle-Based Drug Delivery
- Animal Nutrition and Physiology
- Effects of Environmental Stressors on Livestock
- Cancer Cells and Metastasis
- Erythrocyte Function and Pathophysiology
- Salmonella and Campylobacter epidemiology
- Bird parasitology and diseases
- Probiotics and Fermented Foods
- Genetic and phenotypic traits in livestock
- Pharmacological Effects and Assays
- Blood properties and coagulation
- Animal Genetics and Reproduction
- Genetically Modified Organisms Research
- Microbial infections and disease research
- Parasitic infections in humans and animals
- Toxoplasma gondii Research Studies
- Ruminant Nutrition and Digestive Physiology
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche
2016-2025
Istituto Superiore di Sanità
2012
University of Urbino
2009
In a market undergoing constant evolution, the production of chicken meat that consumers would perceive as "natural" and "animal friendly" is crucial. The use probiotics in rurally reared chickens could represent major opportunity to achieve mutual benefit for both industry consumers. A total 264 male Kabir chicks were randomly distributed one 2 dietary treatments: L group received commercial feed supplemented with 2.0 g/100 kg Lactobacillus acidophilus D2/CSL, while C same basal diet...
Aims: The half-life of superparamagnetic iron oxide nanoparticles in the bloodstream is very short since they are rapidly taken up by reticuloendothelial system. In this article, we report encapsulation different magnetic into human erythrocytes to increase their blood circulation time. Materials & methods: Newly synthesized and commercially available were evaluated for red cells through transient opening membrane pores controlled hypotonic dialysis successive isotonic resealing...
The current study investigated the effects of Lactobacillus acidophilus and Bacillus subtilis, used as probiotics, on microflora, morphology, morphometry gut in organic laying hens. birds (180 Hy-Line hens) were divided into 3 homogenous groups received a pre-deposition diet from 16 to 20 wk age deposition for remaining 7 months experiment. control group (CTR) was fed corn-soybean cake-based diet, second (L) same supplemented with 0.1% L. while third (B) basal 0.05% B. subtilis. At 18 (T1)...
Salmonella enterica serovar Typhimurium is an important zoonotic gastrointestinal pathogen responsible for foodborne disease worldwide. It a successful enteric because it has developed virulence strategies allowing to survive in highly inflamed intestinal environment exploiting inflammation overcome colonization resistance provided by microbiota. In this study, we used piglets featuring intact microbiota, which naturally develop gastroenteritis, as model salmonellosis. We compared the...
Objectives Naturally occurring tumours in domestic cats are less common than dogs and represent the leading cause of death among older animals. The main objective this study was to analyse a large data set histologically diagnosed highlight most World Health Organization (WHO) tumour histotypes, effect age sex, International Classification Diseases for Oncology (ICD-O) topographical site predilections feline breed-specific tumours. Methods A total 680 European Shorthair by three veterinary...
Mammary tumours are the most common malignancy diagnosed in female dogs and a significant cause of mortality morbidity this species. Carbohydrate antigen (CA) 15–3 is mucinous glycoprotein aberrantly over-expressed human mammary neoplasms one widely used serum tumour markers women with breast cancer. The aim study was to investigate antigenic analogies canine CA assess its expression cancer tissues cell lines. Immunohistochemical evaluated 7 lines 50 malignant tumours. As positive control,...
Dientamoeba fragilis is a common intestinal parasite in humans. Transmission routes and natural host range are unknown. To determine whether pigs hosts, we analyzed 152 fecal samples by microscopy molecular methods. We confirmed that harbor genotypes found humans, suggesting zoonotic potential.
In January 2022, West Nile virus (WNV) lineage 2 (L2) was detected in an adult female goshawk rescued near Perugia the region of Umbria (Italy). The animal showed neurological symptoms and died 15 days after its recovery a wildlife rescue center. This second case WNV infection recorded birds during cold season, when mosquitoes, main vectors, are usually not active. According to National Surveillance Plan, is included amongst low-risk areas. necropsy evidenced generalized pallor mucous...
Superparamagnetic iron oxide nanoparticles (SPIOs) have been produced and used as a potent versatile contrast media for magnetic resonance imaging (MRI). Despite number of efforts to improve their surface chemistry biocompatibility, the SPIOs half life in blood circulation is very short they are rapidly taken up by reticuloendothelial system (RES). In this paper we describe new method that permits avoid rapid clearance SPIOs. Nanoparticles made biocompatible encapsulation into autologous red...
Superparamagnetic iron oxide (SPIO) and ultra small superparamagnetic (USPIO) nanoparticles have been developed as magnetic resonance imaging (MRI) contrast agents. Iron nanoparticles, that become if the core particle diameter is ~ 30nm or less, present R1 R2 relaxivities which are much higher than those of conventional paramagnetic gadolinium chelates. Generally, these particles coated with biocompatible polymers prevent agglomeration colloidal suspension improve their blood distribution...
In poultry production, probiotics have shown promise to limit campylobacteriosis at the farm level, most commonly reported zoonosis in Europe. The aim of this trial was evaluate effects Saccharomyces supplementation Campylobacter jejuni challenged chickens on performance and intestinal ecosystem. A total 156 day old male Ross 308 chicks were assigned a basal control diet (C) or cerevisiae boulardii CNCM I-1079 supplemented (S). All birds orally with C. (d) 21. Live weight growth evaluated...
On the beach of Linosa Island (Italy), forty-three loggerhead sea turtle (Caretta caretta) unhatched eggs were recovered from nests, formalin-fixed and necropsied. The tissue samples stained with Haematoxylin-Eosin (HE), Grocott, von Kossa, Periodic Ac-id-Schiff (PAS), Movat pentachrome stains. Histologically, vacuolar degeneration (100.0%) increased numbers melanomacrophages (18.6%) in liver, edema (14.0%) lungs observed. Twenty-five kidneys (58.1%) showed deposition blue amorphous material...
On the beach of Linosa Island (Italy), 43 loggerhead sea turtle (Caretta caretta) unhatched eggs were recovered from nests, formalin-fixed and necropsied. The tissue samples stained with hematoxylin-eosin (HE), Grocott, von Kossa, periodic acid-Schiff (PAS), Movat pentachrome stains. Histologically, vacuolar degeneration (100.0%) increased numbers melanomacrophages (18.6%) in liver, edema (14.0%) lungs observed. Twenty-five kidneys (58.1%) showed deposition blue amorphous material HE...
It is supposed that fibroblasts present in tumour microenvironment increase cancer invasiveness and its ability to metastasize but the mechanisms have not been clearly defined yet. Thus, current study was designed assess changes gene expression five various cell lines grown as a co-culture with carcinoma-associated (CAFs) vitro. A fibroblast line isolated from canine mammary cancer. Then, of cells CAFs established maintained for 72 hrs. Having sorted cells, global using DNA microarrays...
The aim of this study was to assess the severity and distribution hepatic lipidosis in high-yielding dairy cows during transition period by evaluation body condition score (BCS), serum levels non-esterified fatty acids (NEFA) β-hydroxybutyrate (BHB) histological liver lipid content (GdL). Twenty-seven cows, with a milk production ~10 000 kg per year were enrolled an experiment. Clinical examination performed evaluate health status or presence periparturient diseases after calving. Animals...
Cancer immunosuppression that facilitates tumor progression and metastasis evolves by development of an immunosuppressive network. The aim this study was to assess network in dogs with benign or malignant tumors without confirmed metastasis. authors showed the number various T cell subpopulations constant during development; however regulatory cells (Tregs) significantly higher tumor-bearing than healthy individuals. myeloid-derived suppressor (MDSCs) their p-STAT3 expression (which is a...