Simone M. Cacciò

ORCID: 0000-0002-8561-1323
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About
Contact & Profiles
Research Areas
  • Parasitic Infections and Diagnostics
  • Amoebic Infections and Treatments
  • Viral gastroenteritis research and epidemiology
  • Parasitic infections in humans and animals
  • Toxoplasma gondii Research Studies
  • Dermatological diseases and infestations
  • Genomics and Phylogenetic Studies
  • Coccidia and coccidiosis research
  • Vector-borne infectious diseases
  • RNA and protein synthesis mechanisms
  • Parasites and Host Interactions
  • Cytomegalovirus and herpesvirus research
  • Clostridium difficile and Clostridium perfringens research
  • Forensic and Genetic Research
  • Enterobacteriaceae and Cronobacter Research
  • Evolution and Genetic Dynamics
  • Congenital Anomalies and Fetal Surgery
  • Helminth infection and control
  • RNA Research and Splicing
  • Parasite Biology and Host Interactions
  • Veterinary medicine and infectious diseases
  • Legionella and Acanthamoeba research
  • Viral Infections and Vectors
  • Herpesvirus Infections and Treatments
  • Genomics and Chromatin Dynamics

Istituto Superiore di Sanità
2016-2025

Wellcome Trust
2012

University of Glasgow
2012

New England Disabled Sports
2012

Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche
2012

Magna Graecia University
2005

Université Paris Cité
2000

Institut Jacques Monod
1993-1997

University of Pavia
1992-1993

University of Trieste
1991

Giardia duodenalis, originally regarded as a commensal organism, is the etiologic agent of giardiasis, gastrointestinal disease humans and animals. Giardiasis causes major public veterinary health concerns worldwide. Transmission either direct, through faecal-oral route, or indirect, ingestion contaminated water food. Genetic characterization G. duodenalis isolates has revealed existence seven groups (assemblages A to G) which differ in their host distribution. Assemblages B are found many...

10.1371/journal.pntd.0000558 article EN cc-by PLoS neglected tropical diseases 2009-11-30

Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases. The gut microbiome is a key player in diet-health axis, but while its bacterial fraction widely studied, role micro-eukaryotes, including Blastocystis, underexplored. We performed global-scale analysis on 56,989 metagenomes showed that Blastocystis exhibits distinct prevalence patterns linked to geography, lifestyle, dietary habits. presence defined specific signature was positively...

10.1016/j.cell.2024.06.018 article EN cc-by-nc-nd Cell 2024-07-08

Abstract In Europe, most reported human cases of babesiosis have been attributed, without strong molecular evidence, to infection with the bovine parasite Babesia divergens. We investigated first known in Italy and Austria, which occurred two asplenic men. The complete 18S ribosomal RNA (18S rRNA) gene was amplified from specimens their whole blood by polymerase chain reaction (PCR). With phylogenetic analysis, we compared DNA sequences PCR products those for other spp. were identical...

10.3201/eid0908.020748 article EN cc-by Emerging infectious diseases 2003-08-01

Abstract The influence of unicellular eukaryotic microorganisms on human gut health and disease is still largely unexplored. Blastocystis spp. commonly colonize the gut, but its clinical significance ecological role are currently unsettled. We have developed a high-sensitivity bioinformatic pipeline to detect subtypes (STs) from shotgun metagenomics, applied it 12 large data sets, comprising 1689 subjects different geographic origin, status lifestyle. confirmed extended previous observations...

10.1038/ismej.2017.139 article EN cc-by-nc-sa The ISME Journal 2017-08-22

Parasites are important food-borne pathogens.Their complex lifecycles, varied transmission routes, and prolonged periods between infection symptoms mean that the public health burden relative importance of different routes often difficult to assess.Furthermore, there challenges in detection diagnostics, variations reporting.A Europe-focused ranking exercise, using multicriteria decision analysis, identified potentially parasites importance, currently not routinely controlled food.These...

10.2903/j.efsa.2018.5495 article EN cc-by-nd EFSA Journal 2018-12-01

The cestode Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a fatal zoonotic parasitic disease northern hemisphere. Red foxes are main reservoir hosts and, likely, drivers geographic spread in Europe. Knowledge genetic relationships among E. isolates at European scale key to understanding dispersal characteristics multilocularis. Hence, present study aimed describe diversity obtained from different host species 19 countries. Based on analysis complete...

10.1016/j.ijpara.2024.01.003 article EN cc-by-nc-nd International Journal for Parasitology 2024-01-21

Reductions in annual rainfall some regions and increased human consumption have caused a shortage of water resources at the global level. The recycling treated wastewaters has been suggested for certain domestic, industrial, agricultural activities. importance microbiological parasitological criteria recycled repeatedly emphasized. Among water-borne pathogens, protozoa genera Giardia Cryptosporidium are known to be highly resistant treatment procedures cause outbreaks through contaminated...

10.1128/aem.69.6.3393-3398.2003 article EN Applied and Environmental Microbiology 2003-06-01

Cysts of Giardia duodenalis were collected in Mexico from symptomatic children (n = 9) and pet dogs 5), they directly characterized by nested polymerase chain reaction (PCR) amplification the β-giardin gene. Eight isolates human origin established as vitro cultures 2 reference strains, representing assemblages A B G. duodenalis, also analyzed. PCR–restriction fragment length polymorphism showed that all belonged to assemblage A. Sequence analyses indicated large majority A1 genotype;...

10.1645/ge-293r article EN Journal of Parasitology 2005-02-01
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