Rui Chen

ORCID: 0000-0003-3689-5697
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Research Areas
  • Nonlinear Optical Materials Research
  • Crystal structures of chemical compounds
  • Congenital Heart Disease Studies
  • Synthesis and biological activity
  • Cardiac Structural Anomalies and Repair
  • Solid-state spectroscopy and crystallography
  • Cardiac Valve Diseases and Treatments
  • Chemical synthesis and pharmacological studies
  • Bone health and osteoporosis research
  • Birth, Development, and Health
  • Sexual function and dysfunction studies
  • Parkinson's Disease Mechanisms and Treatments
  • Coronary Artery Anomalies
  • Photochemistry and Electron Transfer Studies
  • Tracheal and airway disorders
  • Congenital Diaphragmatic Hernia Studies
  • Aortic aneurysm repair treatments
  • Hip and Femur Fractures
  • Bacterial Identification and Susceptibility Testing
  • Tuberculosis Research and Epidemiology
  • Connective tissue disorders research
  • Sex and Gender in Healthcare
  • Traumatic Brain Injury Research
  • Porphyrin and Phthalocyanine Chemistry
  • Synthesis and Characterization of Heterocyclic Compounds

Qingdao University
2020-2025

Affiliated Hospital of Qingdao University
2024-2025

Qingdao Women and Children's Hospital
2020-2024

University Hospital Heidelberg
2024

Heidelberg University
2024

Jingning County People's Hospital
2023

China Medical University
2020

Tumor Hospital of Xinjiang Medical University
2005

Xinjiang Medical University
2005

National Heart Hospital
1973

Chalcone structures obtained by structural tailoring are an important class of molecular organic nonlinear optics (NLO) crystals that can be used for multiple purposes. In this work, two novel chalcone compound with non-centrosymmetric structures, 6MN3MPP (C21H18O3, Pca21) and 6MN4MPP Pn), were designed grown extending the π-conjugation structure-modifying strategy. On basis, second harmonic generation (SHG) efficiency, thermal stability, transmission spectra, dielectric constant,...

10.1021/acs.cgd.2c00235 article EN Crystal Growth & Design 2022-06-01

In this study, a new class of organic salt nonlinear optical (NLO) crystals, 2-HDSAI and HDSAI, were synthesized grown by designing adjusting the methyl position on receptor. Single-crystal XRD analysis confirms that crystal belongs to monoclinic group P21. Among them, HDSAI has second harmonic generation (SHG) activity, maximum powder SHG is about 0.7 times OH1. The coefficient d11 = 62 pm/V @1064 nm theoretical calculation. single was successfully slow cooling method. Through study...

10.1021/acs.cgd.2c00523 article EN Crystal Growth & Design 2022-08-30

Traumatic brain injury (TBI), especially the severe TBI are often followed by persistent cognitive sequalae, including decision-making difficulties, reduced neural processing speed and memory deficits. Diffuse axonal (DAI) is classified as one of types TBI. Part DAI patients marginalized from social life due to impairment, even if they rated favorable outcome. The purpose this study was elucidate specific type severity impairment in with outcome.The neurocognition 46 outcome evaluated...

10.3389/fnins.2023.1077858 article EN cc-by Frontiers in Neuroscience 2023-01-25

Controlling the molecular arrangement by introducing halogen element substituents is a very effective crystal design method. Therefore, four chalcone derivatives, EFDAN, ECDAN, EBDAN, and EIDAN, were synthesized F, Cl, Br, I, respectively. The tunable crystals containing Cl Br elements with appropriate size have better spatial arrangement, which conducive to increase of nonlinearity. Theoretical calculations indicate that electron transfer from amino group adjacent benzene ring conjugated...

10.1021/acs.cgd.2c01451 article EN Crystal Growth & Design 2023-03-01

In the design of molecular organic nonlinear optical (NLO) chalcone crystals, how to balance stability crystal structure and π-conjugation length while enhancing NLO activity chromophore remains a challenge. this study, we have synthesized series crystals 6MNPP (C20H16O2, Pca21), 6MN4TP (C21H18O2, 6MN4EP (C22H20O2, 6MN3TP P21) by adding benzene ring in D−π–A−π–D introducing new functional groups with large differences electron-donating ability at both ends molecule. All four are...

10.1021/acs.cgd.2c01191 article EN Crystal Growth & Design 2022-12-22

Sexual activity exists in a complex relationship with human health. This study aims to elucidate the correlation between sexual frequency and incidence of cardiovascular diseases (CVD) all-cause mortality among young middle-aged adults United States. We analyzed 17,243 participants from National Health Nutrition Examination Survey(NHANES)(2005–2016), comparing CVD risks across frequencies using multivariable Logistic Cox regression models. Kaplan-Meier curves assessed survival probability...

10.1038/s41598-024-83414-3 article EN cc-by-nc-nd Scientific Reports 2024-12-30

Purpose: To evaluate the efficacy and safety of 500 mg nemonoxacin administered orally once daily to outpatients with community-acquired pneumonia (CAP). Patients Methods: CAP who received monotherapy were selected from visited Department Pulmonary Critical Care Medicine Shengjing Hospital China Medical University between July December 2018. Their characteristics, pneumonia-related symptoms, treatment effects, adverse reactions recorded. Results: In total, 337 patients for 8.24 ± 3.73 days....

10.2147/idr.s248092 article EN cc-by-nc Infection and Drug Resistance 2020-07-01

Abstract Background “ Swiss Cheese ” ventricular septal defects (VSDs) is a kind of rare and complex congenital heart the surgical management remains controversial challenge. We reviewed our preliminary clinical experience on biventricular repair “Swiss Cheese” VSDs with two-patch right ventricle apex excluding technique in 10 cases. Methods From May 2014 to December 2019, series patients (M/F = 3/7) were admitted center. Nine cases underwent one-stage 1 case received two-stage same...

10.1186/s13019-021-01399-w article EN cc-by Journal of Cardiothoracic Surgery 2021-03-20

We have analysed the bacteraemias occurring before discharge from hospital in patients subjected to open-heart surgery. The overall incidence was 2·7%. predominant organisms at first were staphylococci and streptococci, but later years of study almost all positive blood cultures due Gram-negative bacilli. Short-term prophylactic antibiotics used throughout. Eleven 12 Gram-positive occurred after period antibiotic prophylaxis; eight had endocarditis a further three serious wound infections....

10.1136/thx.28.2.183 article EN Thorax 1973-03-01

Abstract A type of organic nonlinear optical (NLO) material EBQ‐T (2‐(4‐ethoxystyryl)‐1‐methyl‐quinolinium 4‐methylbenzenesulfonate) is synthesized, and the crystal with a size 11 × 5 2 mm 3 grown by evaporation method in methanol. Single X‐ray diffraction (XRD) analysis confirms that belongs to non‐centrosymmetric Cc space group, edge molecular orbital energy gap (HOMO‐LUMO) calculated. Proton nuclear magnetic resonance ( 1 H NMR) fourier transform infra‐red (FT‐IR) tests further verify...

10.1002/crat.202200003 article EN Crystal Research and Technology 2022-05-07
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