A5084555594- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Ectopic Pregnancy Diagnosis and Management
- Healthcare Education and Workforce Issues
- Education and Learning Interventions
- Circadian rhythm and melatonin
- Ovarian cancer diagnosis and treatment
- Gestational Trophoblastic Disease Studies
- Neuroendocrine regulation and behavior
- Hernia repair and management
- Food Quality and Safety Studies
- Cardiac Fibrosis and Remodeling
- Reproductive System and Pregnancy
- Stress Responses and Cortisol
- Intraperitoneal and Appendiceal Malignancies
- Educational Systems and Policies
- Radiation Dose and Imaging
- Photodynamic Therapy Research Studies
- Minimally Invasive Surgical Techniques
- Child Therapy and Development
- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Reproductive Health and Contraception
- Estrogen and related hormone effects
- Intestinal and Peritoneal Adhesions
Ulsan University Hospital
2019-2025
University of Ulsan
2009-2025
Ulsan College
2009-2025
Yonsei University
2012-2024
Chungbuk National University Hospital
2020-2024
Ulsan National Institute of Science and Technology
2022
Chungbuk National University
2022
Gwangju Health University
2014-2021
Gangnam Severance Hospital
2017-2019
Gyeongsang National University
2017
Neurons in the suprachiasmatic nucleus (SCN) are responsible for generation of circadian oscillations, and understanding how these neurons communicate to form a functional circuit is critical issue. The neurotransmitter GABA its receptors widely expressed SCN where they mediate cell-to-cell communication. Previous studies have raised possibility that can function as an excitatory transmitter adult during day, but this work controversial. In present study, we first tested hypothesis evoke...
In 2008, the Korean Centers for Disease Control and Prevention (KCDC) initiated Community Health Survey (KCHS), first nationwide survey to provide data that could be used plan, implement, monitor evaluate community health promotion disease prevention program. This community-based cross-sectional has been conducted by 253 centers, 36 universities 1,500 interviewers. The KCHS standardized questionnaire is developed jointly KCDC staff, a working group of indicators standardization subcommittee...
In mammals, the increased secretion of arginine-vasopressin (AVP) (antidiuretic hormone) and oxytocin (natriuretic is a key physiological response to hyperosmotic stress. this study, we examined whether chronic stress weakens GABA(A) receptor-mediated synaptic inhibition in rat hypothalamic magnocellular neurosecretory cells (MNCs) secreting these hormones. Gramicidin-perforated recordings MNCs acute slices prepared from control rats ones subjected revealed that challenge not only attenuated...
Increased arginine-vasopressin (AVP) secretion is a key physiological response to hyperosmotic stress and may be part of the mechanism by which high-salt diets induce or exacerbate hypertension.Using deoxycorticosterone acetate-salt hypertension model rats, we sought test hypothesis that changes in GABA(A) receptor-mediated inhibition AVP-secreting magnocellular neurons contribute generation Na(+)-dependent hypertension.In vitro gramicidin-perforated recordings paraventricular supraoptic...
The resetting of the circadian clock based on photic cues delivered by glutamatergic retinohypothalamic tract is an important process helping mammals to function adaptively daily light-dark cycle. To see if relies voltage-gated Ca(2+) channels (VGCCs), we examined effects VGCC blockers glutamate-induced phase shifts firing activity rhythms suprachiasmatic nucleus (SCN) neurons in hypothalamic slices. First, found that a cocktail amiloride, nimodipine and omega-conotoxin MVIIC (T-, L-...
Increased secretion of oxytocin and arginine vasopressin (AVP) from hypothalamic magnocellular neurosecretory cells (MNCs) is a key physiological response to lactation. In the current study, we sought test hypothesis that GABAA receptor-mediated inhibition MNCs altered in lactating rats. Gramicidin-perforated recordings rat supraoptic nucleus (SON) slices revealed reversal potential (EGABA) was significantly depolarized rats as compared virgin animals. The depolarizing EGABA shift much...
This research introduced a strategy to fabricate sub-millimeter-diameter artificial liver tissue by extruding combination of decellularized extracellular matrix (dECM), alginate, endothelial cells, and hepatocytes. Vascularization remains critical challenge in engineering, as replicating the liver’s intricate vascular network is essential for sustaining cellular function viability. Seven scaffold groups were evaluated, incorporating different cell compositions, materials, structural...
In this report, we present a novel virtual high-throughput screening methodology to assist in computer-aided drug discovery. Our method, designated as SLIM, involves ligand-free shape and chemical feature matching. The procedure takes advantage of negative image binding pocket target receptor. is set atoms representing the inner features pocket. Using image, SLIM implements shape-based similarity search based on molecular volume superposition for ensemble conformers each molecule. superposed...
Allogeneic hematopoietic stem-cell transplantation (HCT) is the only curative option for most hematologic malignancies. However, HSCT can cause early menopause and various complications in premenopausal women. Therefore, we aimed to investigate risk factors predicting its clinical implications among survivors post HCT.We retrospectively analyzed 30 adult women who had received HCT at status between 2015 2018. We excluded patients autologous stem cell transplantation, relapsed, or died of any...
Green tea leaves were fermented for 15 and 30 days with Monascus pilosus which is known to produce functional statins (TMs), the content of various biochemical constituents such as total polyphenol (TP), flavonoid (TF), theaflavin, thearubigin analyzed compared that non-fermented green (GT) Pu-erh Chinese post-fermented (PU). In addition electron donating ability (EDA), ferric iron reducing power (FIRP), xanthine oxidase (XO) inhibitory activity, superoxide dismutase (SOD)-like chelating...
<b><i>Aims:</i></b> Our objective was to predict natural pregnancy after endometriosis surgery using the fertility index (EFI). <b><i>Methods:</i></b> A retrospective medical records review conducted, examining patients surgically treated for at a single center in Korea between January 2009 and February 2015. In total, 68 women attempting conception were analyzed by assessing age, preoperative serum CA-125, body mass index, revised American...
For acute adnexal torsion of pregnant women, appropriate treatment based on an accurate diagnosis is especially important for fertility preservation and timely treatment. The 2017 American College Obstetricians Gynecologists (ACOG) Committee Opinion No. 723 announced its practice-changing guidelines to ensure that diagnostic magnetic resonance imaging (MRI) conducted during the first trimester gadolinium exposure at any time pregnancy are safe fetal stability. Unfortunately, few studies have...
The East Asian VLBI Network (EAVN) is an international facility in Asia and operated under mutual collaboration between countries, as well part of Southeast European countries. EAVN currently consists 16 radio telescopes three correlators located China, Japan, Korea, mainly at frequency bands, 6.7, 22, 43 GHz with the longest baseline length 5078 km, resulting highest angular resolution 0.28 milliarcseconds GHz. One distinct capabilities multi-frequency simultaneous data reception nine...
Objective This study aimed to introduce a method remove huge ovarian tumors (≥15 cm) intact with single-port laparoscopic surgery (SPLS) using SW Kim's technique and compare the surgical outcomes those of laparotomy. Methods Medical records were retrospectively reviewed for patients who underwent either SPLS (n=21) specially designed 30×30-cm2-sized 3XL LapBag or laparotomy (n=22) tumor from December 2008 May 2016. Perioperative compared. Results In 19/21 (90.5%) patients, was successfully...
Objective The objective of this study was to evaluate clinical and laboratory characteristics torsion on mature cystic teratomas (MCTs). In addition, we examined whether these factors could be helpful in diagnosing MCT torsion. Methods A retrospective medical record review conducted for 384 patients who had undergone surgery histologically verified ovarian MCTs at single university hospital between July 2006 May 2017. Patients with or without groups were compared respect presentation,...
The present study assessed the safety and benefits of laparoscopic-assisted adenomyomectomy compared to laparoscopic or laparotomic adenomyomectomy.This was a retrospective comparative study. A total 277 patients underwent between January 2016 2019 at Department Obstetrics Gynaecology, Ulsan University Hospital, including 25 with adenomyomectomy, 82 170 adenomyomectomy. Laparoscopic-assisted consisted uterine artery procedure reduce blood loss minimal incisional for An additional surgery...
Aims: The cellular and molecular mechanisms safety after drug-eluting stent (DES) implantation in diabetic patients are still poorly understood; therefore, this study, we evaluated the pathologic responses of sirolimus-eluting (SES) or paclitaxel-eluting (PES) a type I diabetes mellitus (DM) rat model.Methods: DM model was manipulated by intra-peritoneal streptozotocin injection. Two weeks later, DES implanted aorta rats with hyperglycemia not as control. Four implantation, stented isolated...