A5040937162- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Uterine Myomas and Treatments
- Ovarian function and disorders
- Ovarian cancer diagnosis and treatment
- Gynecological conditions and treatments
- Bone health and osteoporosis research
- Reproductive Biology and Fertility
- Estrogen and related hormone effects
- Endometrial and Cervical Cancer Treatments
- Vitamin D Research Studies
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and preeclampsia studies
- Menopause: Health Impacts and Treatments
- Pregnancy and Medication Impact
- Folate and B Vitamins Research
- Pregnancy-related medical research
- Ginseng Biological Effects and Applications
- Intraperitoneal and Appendiceal Malignancies
- Iron Metabolism and Disorders
- GDF15 and Related Biomarkers
- Intestinal and Peritoneal Adhesions
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Contraception
- Pluripotent Stem Cells Research
Yonsei University
2016-2025
Gangnam Severance Hospital
2016-2025
Yong In University
2024
Severance Hospital
2005-2023
Yale University
2015-2022
Yonsei University Health System
2013-2019
CHA University
2019
Chonnam National University
2011
Asan Medical Center
2010
Ajou University
2009
Abstract Ovulatory disorders are common causes of amenorrhea, abnormal uterine bleeding, and infertility, frequent manifestations polycystic ovary syndrome (PCOS). There many potential contributors to ovulatory dysfunction that challenge clinicians, trainees, educators, those who perform basic, translational, clinical, epidemiological research. Similarly, therapeutic approaches potentially involve a spectrum lifestyle, psychological, medical, procedural interventions. Collaborative research,...
Non-ablative 1550-nm erbium-doped fractional photothermolysis systems (FPS) and 10 600-nm carbon dioxide laser (CO(2) FS) have been effectively used to treat scars.We compared the efficacy safety of single-session treatments FPS CO(2) FS for acne scars through a randomized, split-face, evaluator-blinded study.Eight patients with were enrolled in this study. Half each subject's face was treated other half FS. We quartile grading scale evaluations.At 3 months after treatment, mean grade...
Although phthalates were shown to have several negative effects on reproductive function in animals, its role the pathogenesis of endometriosis remains be elucidated.We aimed investigate vitro and vivo di-(2-ethylhexyl)-phthalate (DEHP) compare urinary levels phthalate metabolites between women with without endometriosis.For experimental studies, we used endometrial cell culture nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse models. We also performed a prospective...
To evaluate associations between aromatase inhibitor (AI) treatment and let-7-family microRNA expression in endometriosis.
<b><i>Objectives:</i></b> To compare plasma kisspeptin, serum leptin, and retinol-binding protein 4 (RBP4) levels in women with without polycystic ovary syndrome (PCOS) to correlate these among each other clinical, hormonal, metabolic parameters. <b><i>Methods:</i></b> Ninety women, including 54 PCOS 36 PCOS, participated this study. For all patients, history physical examinations were performed blood samples collected between days 3 8 of a...
Recently, proteomic technologies have demonstrated that several proteins are differently expressed in various body fluids of patients with endometriosis compared those without this condition. The aim study was to investigate secreted urine using techniques order identify potential markers for the clinical diagnosis endometriosis. Urine samples were collected from women undergoing laparoscopy different indications including pelvic masses, pain, suspicious endometriosis, infertility and...
In Brief Objective The aim of this study was to evaluate the effects red ginseng (RG) on menopausal symptoms and cardiovascular risk factors in postmenopausal women. Methods A randomized, placebo-controlled, double-blind clinical trial conducted with women between ages 45 60 years. total 72 were randomly assigned either an RG group (supplemented 3 g RG, including mg ginsenosides, per day) or a placebo for 12 weeks. We analyzed changes (the Kupperman index menopause rating scale), (lipid...
This study aimed to investigate the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome along with its associated risk factors in Korean postmenopausal women. was performed using data from KNHANES 2008-2010 included 4,364 Clinical other objective characteristics, seasonality, presence five components were evaluated correlated 25(OH)D. Although no statistically significant associations observed 25(OH)D prevalence syndrome, adjusted OR for elevated blood...
The aim of this study was to compare intrafollicular biomarkers thiol-redox system and chronic inflammation in infertile patients with without endometriosis, examine correlations between IVF outcomes. included 65 receiving IVF: 31 endometriosis vs 34 endometriosis. Follicular fluid (FF) obtained from a single-dominant follicle during oocyte retrieval stored at -70 °C. Malondialdehyde, superoxide dismutase, glutathione (GSH), peroxidase 3 (GPX3), thioredoxin (TRX), TRX-binding protein 2...
To evaluate risk factors leading to non-alcoholic fatty liver disease (NAFLD) occurrence in polycystic ovarian syndrome (PCOS) women. A retrospective cohort study of a total 586 women diagnosed with PCOS aged 13-35 years at the gynecology department university hospital was done phenotype, metabolic (MetS) diagnosis, body composition, insulin sensitivity, sex hormones, lipid profile, function, and transient elastography (TE). In NAFLD compared those without, MetS diagnosis (Hazard ratio [HR]...
Ovulatory disorders are common causes of amenorrhea, abnormal uterine bleeding and infertility frequent manifestations polycystic ovary syndrome (PCOS). There many potential contributors to ovulatory dysfunction that challenge clinicians, trainees, educators, those who perform basic, translational, clinical epidemiological research. Similarly, therapeutic approaches potentially involve a spectrum lifestyle, psychological, medical procedural interventions. Collaborative research, effective...
The aim of this study was to evaluate serum and urinary levels vascular endothelial growth factors, tumor necrosis factor-alpha (TNF-alpha), soluble fms-like tyrosine kinase (sFlt-1) in patients with endometriosis.During surgery for pelvic pain, mass or infertility, urine were collected. Of 70 patients, 46 had histology-proven endometriosis 24 without participated as controls.Serum TNF-alpha sFlt-1 corrected creatinine excretion significantly increased the group (P=0.001 P=0.011...
The aims of this study were to assess changes in muscle mass and strength according bone mineral density (BMD) after alendronate-calcitriol therapy subsequent common biomarkers for osteoporosis sarcopenia establish a strategy against these coexisting conditions.Thirty-eight women with osteopenia without conditions affecting calcium metabolism, inflammatory cytokines, acute chronic medical conditions, regular endurance exercise completed the study. Appendicular lean BMD measured, relative...
Oxidative stress has been proposed as a potential factor associated with the establishment and progression of endometriosis. Although few studies have shown possible mechanisms which may play roles in development, endometriosis, are known regards initiation disease, especially relationship endometrium. The aim our study was to investigate whether normal endometrium be changed by Damage-associated molecular patterns (DAMPs), contribute developing pathologic induce Endometrial tissues were...
The aim of this study was to assess the correlation between bone mineral density (BMD), arterial stiffness, and coronary atherosclerosis in healthy postmenopausal women.We performed a retrospective review 152 women who visited health promotion center for routine checkup, after excluding participants had factors affecting BMD artery disease. evaluated by dual-energy x-ray absorptiometry lumbar spine femur. Arterial stiffness measured brachial-ankle pulse wave velocity (baPWV), assessed 64-row...
Problem The aim of this study was to evaluate osteopontin (OPN) mRNA expression in eutopic endometrium and plasma OPN levels patients with endometriosis. Method A total 79 histologically confirmed endometriosis 43 without participated study. endometrial tissues measured by real‐time quantitative polymerase chain reaction (PCR) concentrations were quantified using a specific commercial sandwich enzyme‐linked immunosorbent assays (ELISA). Results Osteopontin tissue significantly higher women...
The purpose of this study is to evaluate the level and pattern cyclooxygenase-2 (Cox-2) expression in endometriosis investigate correlation between Cox-2 several clinicosurgical parameters.Twenty-six patients with 21 other benign gynecological conditions were enrolled. eutopic endometrium was sampled by pipelle, fragments ovarian endometrioma non-endometriotic cysts during surgery. Total RNA isolation semiquantitative reverse transcriptase polymerase chain reaction performed.The mRNA (mean...