A5086445897- Phytochemicals and Antioxidant Activities
- Heavy Metals in Plants
- Phytochemistry Medicinal Plant Applications
- Carcinogens and Genotoxicity Assessment
- Agricultural and Food Sciences
- Antioxidant Activity and Oxidative Stress
- Laser Applications in Dentistry and Medicine
- Tryptophan and brain disorders
- Genomics, phytochemicals, and oxidative stress
- Air Quality and Health Impacts
- Pesticide Exposure and Toxicity
- Reproductive Biology and Fertility
- Medical and Biological Ozone Research
- Ginkgo biloba and Cashew Applications
- Tea Polyphenols and Effects
- Spaceflight effects on biology
- Botanical Research and Applications
- Natural Antidiabetic Agents Studies
- Essential Oils and Antimicrobial Activity
- Sirtuins and Resveratrol in Medicine
- Fungal Biology and Applications
- Nutritional Studies and Diet
- Sperm and Testicular Function
- Telomeres, Telomerase, and Senescence
- Health and Lifestyle Studies
Universidade de Caxias do Sul
2016-2025
Pfizer (United Kingdom)
2021
Canada Research Chairs
2016
University of Toronto
2016
University of New Brunswick
2016
Cryopreservation of human semen can cause DNA damages, which compromise the fertilization and normal embryo development. The present study showed that antioxidant resveratrol prevents these damages both in fertile infertile men. addition ascorbic acid before cryopreservation reduce only Although further studies are needed, work could be considered procedures to avoid/minimize preserve sperm integrity.
Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, food condiment and tea-beverage for the treatment several disorders. The objective this study was to characterize chemical compounds hydroalcoholic (ExtHS) aqueous (ExtAS) extract from (L.) by gas chromatography-mass spectrometry (GC-MS) high-resolution electrospray ionization mass (ESI-QTOF MS/MS), evaluate vitro ability scavenge free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•)...
Epilepsy, which is one of the most common neurological disorders, involves occurrence spontaneous and recurrent seizures that alter performance brain affect several sensory behavioral functions. Oxidative damage has been associated with post-seizure neuronal injury, thereby increasing an individual's susceptibility to neurodegenerative disorders. The present study investigated possible anticonvulsive neuroprotective effects organic conventional yerba mate (Ilex paraguariensis), a plant rich...
The aim of this study was to characterise the bioactive compounds in mate (Ilex paraguariensis St. Hil) extract and concentrated obtained by nanofiltration (NF). Also, impact NF on antioxidant activity both extracts evaluated vitro using eukaryotic cells Saccharomyces cerevisiae (yeast assay). results showed a significant increase contents total phenolics (338%), chlorogenic acid (483%), theobromine (323%), caffeine (251%), chlorophyll (321%), condensed tannins (278%) saponins (211%)...
Occupational exposure to pesticides in tobacco fields causes genetic damage farmers. The aim of this study was analyze farmers chronically exposed low doses and nicotine (present the leaves) relation absolute telomere length (aTL), explore influence lifestyle characteristics, oxidative stress, inorganic element levels. DNA isolated from peripheral blood samples agricultural workers non‐exposed individuals, aTL measured by quantitative real time polymerase chain reaction (qPCR) analysis....
Tobacco farming is an important economic income in Brazil, although it has been challenged as regard the occupational exposure to both pesticides and nicotine endured by farmers. Chronic complex mixtures can lead health hazardous. We examined genomic instability epigenetic changes tobacco farmers occupationally exposed pesticide at fields. DNA damage was assessed alkaline comet assay blood cells. Genomic isolated, telomere length measured using quantitative polymerase chain reaction assay....
ABSTRACT Depression is characterized by physical or psychological distress and in many cases can lead to suicide. Objective: assess the prevalence of depression its possible relationship with dietary total antioxidant capacity (DTAC) nutritional parameters climacteric women participating an extension university program a Southern Brazilian city. Methods: data were obtained through questionnaires anthropometric measurements. Diet was assessed using 24-hour recall. The Beck Inventory (BDI)...
Natural products are among one of the most promising fields in finding new molecular targets cancer therapy. Laryngeal carcinoma is common cancers affecting head and neck regions, associated with high morbidity rate if left untreated. The aim this study was to examine antiproliferative effect Araucaria angustifolia on laryngeal HEp-2 cells. results showed that A. extract (AAE) induced a significant cytotoxicity cells compared non-tumor human epithelial (HEK-293) cells, indicating selective...
Polyphenols are natural products with recognized potential in drug discovery and development. We aimed to evaluate the polyphenolic profile of Araucaria angustifolia bracts, their ability scavenge reactive species. The antioxidant antigenotoxic effects A. polyphenols MRC5 human lung fibroblast cells were also explored. total polyphenol extract was determined by Folin-Ciocalteu reagent chemical composition confirmed HPLC. Reactive oxygen species' scavenging investigated...
The Araucaria angustifolia (Bertolini, Otto Kuntze) tree belongs to the family Araucariaceae and is known as Brazilian pine. female strobilus consists of seeds (the edible part A. angustifolia) bracts (non-developed seeds). These bracts, which represent approximately 80% strobilus, have no use. It has previously been suggested that dietary intake antioxidants could be a useful strategy reduce incidence diseases associated with oxidative stress, such cancer, atherosclerosis neurodegenerative...
Lippia alba is a shrub found in all regions of Brazil and other countries South Central America. L. exhibits variability among its different accessions, showing differences morphology the composition essential oil. This study evaluated phenolic profiles antioxidant activities seven accessions alba. The studied exhibited an important content, demonstrated activity with efficacies. main flavonoids were apigenin, luteolin, naringin rutin. Santa Vitória do Palmar accession higher total content....