A5063635728- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Mosquito-borne diseases and control
- Cell Adhesion Molecules Research
- Immunodeficiency and Autoimmune Disorders
- Insect and Arachnid Ecology and Behavior
- Gut microbiota and health
- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- Immune responses and vaccinations
- Immunotherapy and Immune Responses
- Neurobiology and Insect Physiology Research
- Escherichia coli research studies
- Clostridium difficile and Clostridium perfringens research
Center for Research and Advanced Studies of the National Polytechnic Institute
2021-2024
Instituto Politécnico Nacional
2021-2023
Typical enteroaggregative Escherichia coli (tEAEC) is a diarrheagenic E. pathotype associated with pediatric and traveler's diarrhea. Even without diarrhea, EAEC infections in children also lead to increased gut inflammation growth shortfalls. strain's defining phenotype the aggregative adherence pattern on epithelial cells attributable fimbriae (AAF). only causes diarrhea humans; therefore, not much known of exact intestinal region infection damage or its interactions enterocytes vivo situ....
Flying is an essential function for mosquitoes, required mating and, in the case of females, to get a blood meal and consequently as vector. Flight depends on action indirect flight muscles (IFMs), which power wings beat. No description development IFMs including Aedes aegypti, available.A. aegypti thoraces larvae 3 4 (L3 L4) instars were analyzed using histochemistry bright field microscopy. IFM primordia from L3 L4 pupal adult stages dissected processed detect F-actin labelling with...
Lrba is a cytoplasmic protein involved in vesicular trafficking. Lrba-deficient (Lrba-/-) mice exhibit substantially higher levels of IgA both serum and feces than wild-type (WT) mice. Transforming growth factor β1 (TGFβ1) its receptors (TGFβR I II) essential for differentiating IgA+ B cells. Furthermore, increased production suggests potential connection between the TGFβR signaling pathway production. However, specific function cell biology remains unknown. Given Lrba-/- mice, goal this...
γδT intraepithelial lymphocyte represents up to 60% of the small intestine compartment. They are highly migrating cells and constantly interact with epithelial cell layer lamina propria cells. This migratory phenotype is related homeostasis intestine, control bacterial parasitic infections, shedding induced by LPS. Here, we demonstrate that Myo1f participates in adhesion migration lymphocytes. Using long-tailed class I myosins KO mice, identified requirement for their The absence affects...
Introduction Patients with Human Hyper IgM syndromes (HIGM) developed pulmonary and gastrointestinal infections since infancy most patients have mutations in the CD40 ligand (CD40L) gene. Most HIGM compared to healthy subjects higher/similar lower IgG, IgA serum concentrations but gut antibody are unknown. CD40L on activated T-cells interacts B-cells, essential for formation of germinal centres (GCs) inside secondary lymphoid organs (SLOs), where high-affinity antibodies, long-lived...
ABSTRACT γδT intraepithelial lymphocyte represents up to 60% of the small intestine compartment. They are highly migrating cells and constantly interact with epithelial cell layer lamina propria cells. This migratory phenotype is related homeostasis intestine, control bacterial parasitic infections, shedding induced by LPS. Here, we demonstrate that Myo1f participates in adhesion migration lymphocytes. Using long-tailed class I myosins KO mice, identified requirement for their The absence...
Dengue is a worldwide expanding threat caused by dengue virus (DENV) infection. To date, no specific treatment or effective vaccine available. Antibodies produced plasma cells (PCs) might be involved concomitantly in protection and severe immunopathology. Although massive appearance of PCs has been reported during acute DENV infection humans, this response poorly characterized. Here, we show the dynamic PC generation immune-competent mice cutaneously inoculated with compared two control...