Acute lymphoblastic leukemia (ALL) represents around 70% of pediatric leukemia. In high-income countries, the 5-year survival is above 90%, but in low- and middle-income countries inferior. This study documents treatment outcome prognostic factors ALL Pakistan.In this prospective cohort study, all newly diagnosed patients with ALL/lymphoblastic lymphoma from age 1 to 16 years enrolled between January 1, 2012, December 31, 2021, were included. The was based on standard arm UKALL2011...

Objective: To assess the prevalence of anemia among pregnant women attending a healthcare facility in Multan and identify its associated sociodemographic determinants.Study Design: A cross-sectional study.Place Duration Study: This study was conducted at Department Obstetrics Gynecology Medicine, Bakhtawar Amin Trust Hospital Multan, Pakistan, from January 2021 to 2022.Methods: The included 250 selected by consecutive sampling. sample size calculated keeping estimated incidence 40%, 5%...

Objective: To compare the outcome of nasal packing and intranasal pressure splints in patients undergoing septoplasty. Study design: Randomized controlled trial.Place Duration Study: The study was carried out at otorhinolaryngology department Combined Military Hospitals, Bahawalpur Murree from June 2010 to November 2011.Methods: A total 160 aged 15 50 years, septoplasty, were included distributed two equal groups. Group with packing, compared group B which placed no done. Post operative...

Objective: The objective of our study was to assess the incidence ACEinhibitor induced cough in population. Study Design: Mainly prospective, multicenter, open labeled 500patients. Setting: Department Medicine Combined Military Hospital (CMH) Lahore and PNS SHIFA (NavalHospital) Karachi. Period February 2000 2001. Material Method: 500 Patients using eight differenttypes ACE inhibitors were selected an especially designed Performa completed. In this preferencewas given patients whom...

Acute leukemia is a fast-growing, overpopulated clone of immature proliferating cells that largely predominate in the bone marrow and have capacity to prolong life indefinitely. Upon inspection cytologic assessment or peripheral blood, demonstrate quantified uncertainties. Objective: To determine frequency complete remission after induction 7+3 chemotherapy patients with acute myeloid leukemia. Methods: The nature this study was cross sectional at Department Oncology, Pakistan Institute...

Background: Betulinic acid (BA) has been proven to contain diverse functions such as anti-cancer effects, anti-HIV, anti-bacterial, anti-inflammatory, anti-malarial, anti-helminthic, and other pharmaceutical properties. The objective of this study was assess the immunomodulatory effects BA on ovalbumin induced airway inflammation in male mice. Methods: Forty healthy BALB/c mice were randomly divided into 4 groups. Group I served normal control (NC) group. II asthmatic (AC) group sensitized...

Objective: To evaluate the proportion of depression amongst epilepticpatients. Study design: Cross-sectional study. Setting: The study was carried out in CMH Pano Aqil Period:September 2003 to September 2004. Material and Methods: One hundred consecutive cases primary epilepsy fromthe outpatient department were included sample. Patients with severe physical or mental disability wereexcluded from Standardized translated Urdu version Beck Depression Inventory used evaluatedepression. ICD-10...

Background Acute Lymphoblastic Leukemia (ALL) represents around 70% of pediatric leukemia. In high-income countries, 5-year survival is above 90% but in low-and middle-income countries inferior. Objective: To document the treatment outcome and prognostic factors Pediatric ALL Pakistan. Materials methods : this descriptive study, all newly diagnosed cases ALL/LBL from one to 16 years age enrolled between 1 January 2012 31 December 2021 were included. The was based on standard arm UKALL2011...

Objective: To compared efficacy of alpha lipoic acid (antioxidant medication) and aloe vera gel together versus intralesional steroids (hydrocortisone) in management oral submucous fibrosis by evaluating post treatment clinical features mouth opening burning sensation.
 Study Design: A prospective comparative study.
 Place Duration Study: Department ENT, Combined Military Hospital, Malir Karachi, from Jul 2018 to Mar 2020.
 Methodology: Twenty-eight patients were involved the...

The objective of this study was to determine the blood groups among patients presenting with ischemic stroke either AB group or O is more common (frequent) these irrespective other known factors responsible for stroke. Study Design: Descriptive, Cross-sectional study. Setting: Department Medicine, Nishtar Hospital Multan. Period: January 2015 August 2015. Materials & Methods: We included total 292 (40-70 years age), documented on CT scan brain both gender (male and female). Blood sample...

Background: Iron deficiency anemia is linked with growth retardation, cognition impairment, reduced interest in daily activities and has been shown to contribute infant mortality. Objectives: To evaluate the effectiveness safety of intravenous iron sucrose treatment children anemia. Methodology: A quasi-experimental study was conducted at Lady Reading Hospital, Peshawar from November 2020 April 2021. Patients younger than 18 years who were refractory conventional therapy included patients...

Purpose: To observe efficacy of Virtual reality technology as a potential treatment for improving vision in anisometropic amblyopia without the need occlusion or penalization. Study design: Experimental case series Place and Duration study: Isra University Hospital, Hyderabad, from Nov 2020 to Oct 2021. Methods: Patients (more than 12 years age), with Anisometropic amblyopia, were included this study. history strabismus, cataract any active ocular surface disease excluded. Unaided visual...

Objective: To study the clinical profile and induction outcome in children diagnosed with T-cell acute lymphoblastic leukaemia lymphoma.
 Study Design: Cross-sectional study.
 Place Duration of Study: Paediatric Oncology Unit, Combined Military Hospital, Rawalpindi Pakistan, from Jan 2012 to Dec 2020.
 Methodology: One hundered twenty-one patients T-ALL LBL were evaluated bone marrow biopsy Contrast-enhanced CT scan active region after chemotherapy Dexamethasone, Vincristine,...

Objective: To assess the level of satisfaction regarding admission process, treatment nursing care and general support services amid patients admitted in various hospital departments.
 Study Design: Hospital-based cross-sectional survey.
 Place Duration Study: Combined Military Hospital, Malir Cantt, from Oct 2018 to Sep 2019.
 Methodology: Data was collected 522 participants. An inpatient feedback form used among patients.
 Result: Out 522, 256 (49%) participants ranked...

Objective: To document cervical node metastasis in oral squamous cell carcinoma (OSCC) of buccal mucosa and analyze the oncological necessity most suitable neck dissection, population a tertiary care hospital.
 Study Design: Descriptive cross-sectional study.
 Place Duration Study: Maxillofacial department, Abbasi Shaheed Hospital, Karachi Pakistan, from Jul 2018 to 2020.
 Methodology: It was study 110 histopathologically proven patients Oral Squamous Cell Carcinoma mucosa....

Objective: To carry out the comparison of effectiveness Epleys manoeuvre and Vestibular Sedative in management benign paroxysmal positional vertigo.
 Study Design: Quasi experimental study.
 Place Duration Study: Department ENT, Combined Military Hospital Peshawar, from Jul 2019 to Dec 2020.
 Methodology: The study was conducted on 60 patients who were diagnosed Benign Paroxysmal Positional Vertigo by Dix Hallpike test. divided into 2 groups 30 each. Group A treated with...

Objective: To compare microdebrider-assisted turbinoplasty versus endoscopic partial turbinectomy in cases of inferior turbinate hypertrophy allergic rhinitis patients terms relief/improvement nasal obstruction, post operative bleeding, crusting and synechie formation.
 Study Design: Quasi experimental study.
 Place Duration Study: Combined Military Hospital Mardan Malir, from Jan 2019 to 2020.
 Methodology: A total 90 with severe obstruction due bilateral fulfilling the...

OBJECTIVE: To determine the frequency of proptosis and associations with demographic, clinical hematological characteristics acute myeloid leukemia (AML) in children. METHODS: This descriptive study was conducted at Combined Military Hospital, Rawalpindi, Pakistan from January 2018 to July 2020. Patients AML between 1-12 years age who presented without orbital granulocytic sarcomas (OGS), selected by non-probability convenience sampling technique were evaluated for proptosis. classified into...