A5100638090- Computational Drug Discovery Methods
- Phytochemistry and Biological Activities
- Phytochemical compounds biological activities
- Nanoparticles: synthesis and applications
- Natural Antidiabetic Agents Studies
- Medicinal Plants and Neuroprotection
- Natural product bioactivities and synthesis
- Cholinesterase and Neurodegenerative Diseases
- Essential Oils and Antimicrobial Activity
- Drug-Induced Hepatotoxicity and Protection
- Synthesis and biological activity
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
- Phytochemistry and Bioactive Compounds
- Ethnobotanical and Medicinal Plants Studies
- Liver Disease Diagnosis and Treatment
- Phytochemicals and Antioxidant Activities
- Vitamin D Research Studies
- Diverse Scientific Research Studies
- Berberine and alkaloids research
- Diet, Metabolism, and Disease
- Gut microbiota and health
- Free Radicals and Antioxidants
- Piperaceae Chemical and Biological Studies
- Flowering Plant Growth and Cultivation
Banaras Hindu University
2013-2025
Indian Institute of Technology BHU
2013-2024
Indian Institute of Technology Indore
2017-2024
Amity University
2018-2024
Galgotias University
2024
Graphic Era University
2024
Medi-Caps University
2023
Ministry of Health and Public Hygiene
2022
Indian Institute of Vegetable Research
2021
Central Drug Research Institute
2008-2018
Selective permeability of the blood-brain barrier limits effective treatment neurodegenerative disorders. In present study, brain-targeted lipid-coated mesoporous silica nanoparticles (MSNs) containing berberine (BBR) were synthesized for Alzheimer's disease (AD). The study involved synthesis Mobil Composition Matter-41 (MCM-41) (MSNs), BBR loading, and lipid coating MSNs (MSNs-BBR-L) in vitro vivo characterization MSNs-BBR-L. liposomes (for coating) prepared by thin-film hydration method....
Vitamin D toxicity, often considered rare, can be life-threatening and associated with substantial morbidity, if not identified promptly.To describe clinical biochemical features, risk factors management of patients vitamin toxicity seen between January 2011 2013.Patients presenting 2013, at single tertiary care centre in Delhi-NCR, India, were included. Evaluation included detailed history tests including serum calcium, phosphorus, creatinine, intact parathyroid hormone 25-hydroxyvitamin...
Premna integrifolia L. is widely distributed in tropical and subtropical regions. In the present study, green silver nanoparticles were synthesized efficiently after mixing 1 mmol/L AgNO3 4% aqueous leaf extract at neutral pH (7.0) 25 min sunlight exposure. The was enriched with polyphenols. It had higher flavonoid (67.23 ± 1.23 µg/mg gallic acid equivalent) than phenolic content (58.10 2.29 rutin equivalent). bio-synthesized characterized by different spectroscopic microscopic studies....
We developed a common feature pharmacophore model using known antiadipogenic compounds (CFPMA). identified rohitukine, reported chromone anticancer alkaloid as potential hit through in silico mapping of the in-house natural product library on CFPMA. Studies were designed to assess rohitukine. Rohitukine was isolated from Dysoxylum binacteriferum Hook. ⬧95% purity. As predicted by CFPMA, rohitukine indeed found be an molecule. inhibited lipid accumulation and adipogenic differentiation...
Selective permeability of the blood-brain barrier restricts treatment efficacy neurologic diseases. Berberine (BBR) and curcumin (CUR)-loaded transferosomes (TRANS) were prepared for effective management Alzheimer's disease (AD). The study involved syntheses BBR-TRANS, CUR-TRANS, BBR-CUR-TRANS by film hydration method. Vesicles characterized to ensure formation drug-loaded vesicles their in vivo performance. particle sizes 139.2 ± 7, 143.4 8, 165.3 6.5 nm, respectively. presence diffused...
In the present study, catalytic degradation of selected toxic dyes (methylene blue, 4-nitrophenol, 4-nitroaniline, and congo red) using biosynthesized green silver nanoparticles (AgNPs) Cestrum nocturnum L. was successfully performed. These AgNPs are efficiently synthesized when a reaction mixture containing 5 mL aqueous extract (3%) 100 nitrate (1 mM) is exposed under sunlight for min. The synthesis confirmed based on change in color from pale yellow to dark brown, with maximum absorbance...